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The map label for this gene is hetI [H]

Identifier: 119355935

GI number: 119355935

Start: 100871

End: 101596

Strand: Reverse

Name: hetI [H]

Synonym: Cpha266_0085

Alternate gene names: 119355935

Gene position: 101596-100871 (Counterclockwise)

Preceding gene: 119355936

Following gene: 119355934

Centisome position: 3.24

GC content: 53.31

Gene sequence:

>726_bases
ATGATCATTGCAAAAGAGACCGTTACCCTCATCCATACAGACACGAAAATCCATGGACTGCCCGAAACGGAACTGTACGA
ATCCCTTTCGGACGATGAAAAAACAAGAGCAGGGCGCATCCATGCAGCCAGCGAACGACAGAATTTCATTGTCCGCAGAG
GCATTCTCAGATCCCTTCTGGGAACGACCTTCGGCATCGAGCCCTTCCGGATACGATTCGCCGCCACCCCGGTGGGAAAA
CCGTTCGTCGCATTCCCCGGGAACAGCGGCATCTTTTTCAATCTCTCCCATTCCGGCAACGATATTGTCTATGCTTTTTC
AGGGCACCCCGAAACCGGCATCGACATCGAACGGATACGTACATTAGAGGATATCGACGAACTGGCCAGAAACTACTTCT
CGGCAGAGGAATACGCCATCCTCATGAACCAGCCGGGCTGGAAAAAAAACAATGCCTTCATCAGGATATGGAGCCTCAAG
GAAGCGCTCATCAAAGCCAGCGGCTGGCCTCTCGAACAGGGTCTCGCCGCTTTCGATGTGGCCGCATACTGCCAGATGAA
CCGTTTCGAGTTGCCATTCGGAGACATCCATACCTTCACCTGCATCGCCCCGGTTTTCGACTACATCTGCGGTTTCGCAA
CAGCTCTGGCAATCCGGCTCGACCGGAACGAACCCCTGAACATCAAACGCTACTCTCTGCAGGGCGGACAGTTTTTCGAA
CTCTGA

Upstream 100 bases:

>100_bases
CGGGGCGGTACTGTTATTCGCAGTTATTTGCAGGCAACGGAAGAGAACGATACCTTGTTGAAACAAATCGCCATACCCGC
AAAACAGAAGTCGTCAACCG

Downstream 100 bases:

>100_bases
ACCGAACGTCCGCGATAGACCGACCCCGGCAGAAATTTTCATATCCTTTGTATTCTGATCTCTGAAACAGTCAGAATCAC
ACCCTGAAATCAAATTATTT

Product: 4'-phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MIIAKETVTLIHTDTKIHGLPETELYESLSDDEKTRAGRIHAASERQNFIVRRGILRSLLGTTFGIEPFRIRFAATPVGK
PFVAFPGNSGIFFNLSHSGNDIVYAFSGHPETGIDIERIRTLEDIDELARNYFSAEEYAILMNQPGWKKNNAFIRIWSLK
EALIKASGWPLEQGLAAFDVAAYCQMNRFELPFGDIHTFTCIAPVFDYICGFATALAIRLDRNEPLNIKRYSLQGGQFFE
L

Sequences:

>Translated_241_residues
MIIAKETVTLIHTDTKIHGLPETELYESLSDDEKTRAGRIHAASERQNFIVRRGILRSLLGTTFGIEPFRIRFAATPVGK
PFVAFPGNSGIFFNLSHSGNDIVYAFSGHPETGIDIERIRTLEDIDELARNYFSAEEYAILMNQPGWKKNNAFIRIWSLK
EALIKASGWPLEQGLAAFDVAAYCQMNRFELPFGDIHTFTCIAPVFDYICGFATALAIRLDRNEPLNIKRYSLQGGQFFE
L
>Mature_241_residues
MIIAKETVTLIHTDTKIHGLPETELYESLSDDEKTRAGRIHAASERQNFIVRRGILRSLLGTTFGIEPFRIRFAATPVGK
PFVAFPGNSGIFFNLSHSGNDIVYAFSGHPETGIDIERIRTLEDIDELARNYFSAEEYAILMNQPGWKKNNAFIRIWSLK
EALIKASGWPLEQGLAAFDVAAYCQMNRFELPFGDIHTFTCIAPVFDYICGFATALAIRLDRNEPLNIKRYSLQGGQFFE
L

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17569611, Length=125, Percent_Identity=34.4, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 27213; Mature: 27213

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIAKETVTLIHTDTKIHGLPETELYESLSDDEKTRAGRIHAASERQNFIVRRGILRSLL
CEEECCEEEEEEECCEECCCCHHHHHHHHCCCHHHHCCCEEECCHHHHHHHHHHHHHHHH
GTTFGIEPFRIRFAATPVGKPFVAFPGNSGIFFNLSHSGNDIVYAFSGHPETGIDIERIR
HHHCCCCCEEEEEEECCCCCCEEEECCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHH
TLEDIDELARNYFSAEEYAILMNQPGWKKNNAFIRIWSLKEALIKASGWPLEQGLAAFDV
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHHCCCCCHHHCHHHHHH
AAYCQMNRFELPFGDIHTFTCIAPVFDYICGFATALAIRLDRNEPLNIKRYSLQGGQFFE
HHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEECCCEEEC
L
C
>Mature Secondary Structure
MIIAKETVTLIHTDTKIHGLPETELYESLSDDEKTRAGRIHAASERQNFIVRRGILRSLL
CEEECCEEEEEEECCEECCCCHHHHHHHHCCCHHHHCCCEEECCHHHHHHHHHHHHHHHH
GTTFGIEPFRIRFAATPVGKPFVAFPGNSGIFFNLSHSGNDIVYAFSGHPETGIDIERIR
HHHCCCCCEEEEEEECCCCCCEEEECCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHH
TLEDIDELARNYFSAEEYAILMNQPGWKKNNAFIRIWSLKEALIKASGWPLEQGLAAFDV
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEHHHHHHHCCCCCHHHCHHHHHH
AAYCQMNRFELPFGDIHTFTCIAPVFDYICGFATALAIRLDRNEPLNIKRYSLQGGQFFE
HHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEECCCEEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]