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The map label for this gene is oxaA

Identifier: 118582022

GI number: 118582022

Start: 4005271

End: 4006899

Strand: Reverse

Name: oxaA

Synonym: Ppro_3623

Alternate gene names: 118582022

Gene position: 4006899-4005271 (Counterclockwise)

Preceding gene: 118582023

Following gene: 118582021

Centisome position: 99.97

GC content: 55.92

Gene sequence:

>1629_bases
ATGGAAAAGCGTACTCTGCTGGCAGTCATCCTTTCCATAACCGTTTTTTATGTTTTTTCCCTGCTGTTCGCCCCTGAAAA
GAAACCGGTTCAACCGGAGTCAACGGGACAAGCTGTTTCGGCGCCCGTTTCAGCAGGCCAACCGGTTGCGGGCGGTGTCC
AACCCTCGGCAAGCGCACCCTCGCTGCCAGCGACTGCCCAGCAGCAGGACGTTACCGTACGCACCGGTCTCTATACGGCG
GTTTTCTGCTCGCGCGGTGGCGCGCTGAAGAGCCTGACCCTGAAGAATTACCGCGAGAAGAACCTCCCTGACGCACAAGC
GGTTGTCCTTGGCTCGGATGCTGATCCCTCCGCGCTCACCTTTTCCACTCGTGCGAGCGGTTTCAACCTTCCCGAGGGCG
CTCCCTTTGTCGCCGATGCCACGGCTGTGACCATGGCTGGTGGCGAAAAGAAACAGCTCGTTTTCACCCACAACTCCGGA
CAGGGCTTTACCGTTCGAAAGATCTACACCTTCAGCGGCGATTCGTACGGGATTAAACTTGATACCCAGGTATTCAACAA
CATGGCCGTGCCGCTGGTTGGAACAGTGCAGCAGGTGATGACCTATCCGGGTCTGGTTAAGGCAAAAGACAGCCGTTTCG
AAACAGCTGGCTCCTATCTCTTTAGCGACAACAGCCTGGAGAGCGACAAGCTCAAGGATGTGTCCTCTGCTTCCAAGCTC
TACGACAAGAACCTCCAGTGGTCCGGTTTTGCGGACAAGTATTTCCTCACCGCCATCCTTTCCGAGGGCGGCAGCATCGC
ATCGGTGGAGCTCAGGAAGAACGGAGCCGGGTTCCTGGAGTCCACCGTCTCCTCGCCCCGCATCACGGTCACCCCGGGTC
AGTCGGTCACGGTCGTGCACCGCCTGTTCGTCGGTCCCAAGGATATCGACATTCTTAAGGCCCAGGGCAACTCCCTTGAA
CAATCCCTGGACCTGGGGTGGTTCACGGTCATCGCCAAGCCGCTCCTGTATACACTGAAGTACTTCTACCGCTATGTGGG
CAACTACGGCGTCGCAATCATCATTATTACCATCATTCTCAAGGCTCTCTTCTTCCCCCTGACTCACAAGAGCTACAAGT
CCATGAAGGATATGCAGAAGATCCAGCCGATGATGGCCGCGCTGAAGGAGAAGTACAAGGATGATCGTGAGGGTATGAAC
AAGGCAGTCATGGAACTCTACCGCGATCACAAGGTCAATCCGCTGGGAGGCTGCCTTCCCATGCTGGTCCAGATACCGGT
CTTTTTCGCCCTCTACAAGGCGCTGATGTTCTCCATCGAGCTTCGGCATGCACCTTTCTACTTCTGGATCACCGACCTTT
CCGGCCCGGACAACCTGTTCGGACAGATGCTGGGGCTTCCCTTTGTCATCGGCCCCCTCCCTTTGCTCATGGGCGCCACC
ATGTTCATCCAGCAGAAGATGACGCCTTCCACCATGGACCCGATGCAGGCAAAGATGATGCTCGCTCTCCCCGTGGTCTT
CACGTTCATGTTCCTCAATTTCCCGTCAGGACTGGTCCTGTACTGGTTGCTGAACAACATACTCACCATTGGCCAGCAGA
TGTACATCAATAAACTGGTTAACGACTGA

Upstream 100 bases:

>100_bases
CAGGGGGCTCTGTCTGACCGTGCTGAGAATCTGCAAGTGTCATCCCTTTCATCCTGGCGGATATGACCCCGTACCATAAC
TAGATCAGACTGGAGCTTTC

Downstream 100 bases:

>100_bases
TCCCGGTCGTGGCGGAGTAGCGTCAATGTACATGAGGGATACCATAGCGGCAATCAGCACTCCCCCCGGCAATGGCGGTA
TCGGCATAATCCGGATCAGC

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MEKRTLLAVILSITVFYVFSLLFAPEKKPVQPESTGQAVSAPVSAGQPVAGGVQPSASAPSLPATAQQQDVTVRTGLYTA
VFCSRGGALKSLTLKNYREKNLPDAQAVVLGSDADPSALTFSTRASGFNLPEGAPFVADATAVTMAGGEKKQLVFTHNSG
QGFTVRKIYTFSGDSYGIKLDTQVFNNMAVPLVGTVQQVMTYPGLVKAKDSRFETAGSYLFSDNSLESDKLKDVSSASKL
YDKNLQWSGFADKYFLTAILSEGGSIASVELRKNGAGFLESTVSSPRITVTPGQSVTVVHRLFVGPKDIDILKAQGNSLE
QSLDLGWFTVIAKPLLYTLKYFYRYVGNYGVAIIIITIILKALFFPLTHKSYKSMKDMQKIQPMMAALKEKYKDDREGMN
KAVMELYRDHKVNPLGGCLPMLVQIPVFFALYKALMFSIELRHAPFYFWITDLSGPDNLFGQMLGLPFVIGPLPLLMGAT
MFIQQKMTPSTMDPMQAKMMLALPVVFTFMFLNFPSGLVLYWLLNNILTIGQQMYINKLVND

Sequences:

>Translated_542_residues
MEKRTLLAVILSITVFYVFSLLFAPEKKPVQPESTGQAVSAPVSAGQPVAGGVQPSASAPSLPATAQQQDVTVRTGLYTA
VFCSRGGALKSLTLKNYREKNLPDAQAVVLGSDADPSALTFSTRASGFNLPEGAPFVADATAVTMAGGEKKQLVFTHNSG
QGFTVRKIYTFSGDSYGIKLDTQVFNNMAVPLVGTVQQVMTYPGLVKAKDSRFETAGSYLFSDNSLESDKLKDVSSASKL
YDKNLQWSGFADKYFLTAILSEGGSIASVELRKNGAGFLESTVSSPRITVTPGQSVTVVHRLFVGPKDIDILKAQGNSLE
QSLDLGWFTVIAKPLLYTLKYFYRYVGNYGVAIIIITIILKALFFPLTHKSYKSMKDMQKIQPMMAALKEKYKDDREGMN
KAVMELYRDHKVNPLGGCLPMLVQIPVFFALYKALMFSIELRHAPFYFWITDLSGPDNLFGQMLGLPFVIGPLPLLMGAT
MFIQQKMTPSTMDPMQAKMMLALPVVFTFMFLNFPSGLVLYWLLNNILTIGQQMYINKLVND
>Mature_542_residues
MEKRTLLAVILSITVFYVFSLLFAPEKKPVQPESTGQAVSAPVSAGQPVAGGVQPSASAPSLPATAQQQDVTVRTGLYTA
VFCSRGGALKSLTLKNYREKNLPDAQAVVLGSDADPSALTFSTRASGFNLPEGAPFVADATAVTMAGGEKKQLVFTHNSG
QGFTVRKIYTFSGDSYGIKLDTQVFNNMAVPLVGTVQQVMTYPGLVKAKDSRFETAGSYLFSDNSLESDKLKDVSSASKL
YDKNLQWSGFADKYFLTAILSEGGSIASVELRKNGAGFLESTVSSPRITVTPGQSVTVVHRLFVGPKDIDILKAQGNSLE
QSLDLGWFTVIAKPLLYTLKYFYRYVGNYGVAIIIITIILKALFFPLTHKSYKSMKDMQKIQPMMAALKEKYKDDREGMN
KAVMELYRDHKVNPLGGCLPMLVQIPVFFALYKALMFSIELRHAPFYFWITDLSGPDNLFGQMLGLPFVIGPLPLLMGAT
MFIQQKMTPSTMDPMQAKMMLALPVVFTFMFLNFPSGLVLYWLLNNILTIGQQMYINKLVND

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=501, Percent_Identity=34.1317365269461, Blast_Score=268, Evalue=7e-73,
Organism=Drosophila melanogaster, GI24662345, Length=311, Percent_Identity=23.1511254019293, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356443, Length=311, Percent_Identity=23.1511254019293, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_PELPD (A1AV44)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_903272.1
- ProteinModelPortal:   A1AV44
- STRING:   A1AV44
- GeneID:   4574423
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3623
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   VELYREP
- PhylomeDB:   A1AV44
- ProtClustDB:   CLSK829298
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 59515; Mature: 59515

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x285b8a84)-; HASH(0x286a2974)-; HASH(0x286a7d70)-; HASH(0x28351930)-; HASH(0x286a0294)-; HASH(0x2867ff08)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRTLLAVILSITVFYVFSLLFAPEKKPVQPESTGQAVSAPVSAGQPVAGGVQPSASAP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCC
SLPATAQQQDVTVRTGLYTAVFCSRGGALKSLTLKNYREKNLPDAQAVVLGSDADPSALT
CCCCCCCCCCCEEEHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
FSTRASGFNLPEGAPFVADATAVTMAGGEKKQLVFTHNSGQGFTVRKIYTFSGDSYGIKL
EEECCCCCCCCCCCCCEECCCEEEECCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEEE
DTQVFNNMAVPLVGTVQQVMTYPGLVKAKDSRFETAGSYLFSDNSLESDKLKDVSSASKL
EHHHHCCCCCCHHHHHHHHHHCCCCEECCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHH
YDKNLQWSGFADKYFLTAILSEGGSIASVELRKNGAGFLESTVSSPRITVTPGQSVTVVH
HHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCCCCEEEECCCCCCHHHH
RLFVGPKDIDILKAQGNSLEQSLDLGWFTVIAKPLLYTLKYFYRYVGNYGVAIIIITIIL
HHHCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KALFFPLTHKSYKSMKDMQKIQPMMAALKEKYKDDREGMNKAVMELYRDHKVNPLGGCLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHH
MLVQIPVFFALYKALMFSIELRHAPFYFWITDLSGPDNLFGQMLGLPFVIGPLPLLMGAT
HHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHH
MFIQQKMTPSTMDPMQAKMMLALPVVFTFMFLNFPSGLVLYWLLNNILTIGQQMYINKLV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ND
CH
>Mature Secondary Structure
MEKRTLLAVILSITVFYVFSLLFAPEKKPVQPESTGQAVSAPVSAGQPVAGGVQPSASAP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCC
SLPATAQQQDVTVRTGLYTAVFCSRGGALKSLTLKNYREKNLPDAQAVVLGSDADPSALT
CCCCCCCCCCCEEEHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
FSTRASGFNLPEGAPFVADATAVTMAGGEKKQLVFTHNSGQGFTVRKIYTFSGDSYGIKL
EEECCCCCCCCCCCCCEECCCEEEECCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEEE
DTQVFNNMAVPLVGTVQQVMTYPGLVKAKDSRFETAGSYLFSDNSLESDKLKDVSSASKL
EHHHHCCCCCCHHHHHHHHHHCCCCEECCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHH
YDKNLQWSGFADKYFLTAILSEGGSIASVELRKNGAGFLESTVSSPRITVTPGQSVTVVH
HHCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCCCCEEEECCCCCCHHHH
RLFVGPKDIDILKAQGNSLEQSLDLGWFTVIAKPLLYTLKYFYRYVGNYGVAIIIITIIL
HHHCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KALFFPLTHKSYKSMKDMQKIQPMMAALKEKYKDDREGMNKAVMELYRDHKVNPLGGCLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHH
MLVQIPVFFALYKALMFSIELRHAPFYFWITDLSGPDNLFGQMLGLPFVIGPLPLLMGAT
HHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHH
MFIQQKMTPSTMDPMQAKMMLALPVVFTFMFLNFPSGLVLYWLLNNILTIGQQMYINKLV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ND
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA