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The map label for this gene is ndhI [H]

Identifier: 118581922

GI number: 118581922

Start: 3894950

End: 3895336

Strand: Reverse

Name: ndhI [H]

Synonym: Ppro_3522

Alternate gene names: 118581922

Gene position: 3895336-3894950 (Counterclockwise)

Preceding gene: 118581923

Following gene: 118581921

Centisome position: 97.19

GC content: 57.11

Gene sequence:

>387_bases
ATGAAGATACCGGGGAAGATGGCACACGAGGTGCTGCGGCACTCGGTAATGAAACCGGCCACCTGCAACTATCCGGCTGA
GAAGCAGAAGATGCCGGAGCATTTCCGGGGAAGGATTCGCTACAAGGCCGAGAAGTGCATTGGCTGCAAGTTCTGCGTCC
GCGACTGTCCCGCCAGGGCCATCGAGATCTTCAAGGTGGCTGACAAGGTCTTCGAGGCCAAGTTCTATCTGGACCGCTGC
ATCTACTGCGGCCAGTGTGTGGATTCATGCCCCAAGGATGCCCTGGAGCTGACCCCTGACTTTGAACTGGCCCAGATCGA
CAAGGAGAAGCTGAGGGTTGTATGCAGGAGGGAAGAGGGTGAAGACAAGCCTGAAGAGCCGTCTTGA

Upstream 100 bases:

>100_bases
TCCGAATCGACCAGATGGTGGATTTCTGCTGGCGTTACGTGGCTTCGGCTGCCATGCTCCAGCTTGTGATCGTCATCATT
GCCAAGGGGGTGTTGCCGCA

Downstream 100 bases:

>100_bases
GGGGTGCGAACGGCTGGCGTTGCTGGGAATCGGTTCGGAACTCTGCGCCGACGACGGGGCCGGCATCCTGCTCGTGCGCA
GCCTGCGTTCCCTGATCTGC

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: CO2; H2; oxidized ferredoxin + [C]

Alternate protein names: NAD(P)H dehydrogenase I subunit I; NDH-1 subunit I; NDH-I [H]

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MKIPGKMAHEVLRHSVMKPATCNYPAEKQKMPEHFRGRIRYKAEKCIGCKFCVRDCPARAIEIFKVADKVFEAKFYLDRC
IYCGQCVDSCPKDALELTPDFELAQIDKEKLRVVCRREEGEDKPEEPS

Sequences:

>Translated_128_residues
MKIPGKMAHEVLRHSVMKPATCNYPAEKQKMPEHFRGRIRYKAEKCIGCKFCVRDCPARAIEIFKVADKVFEAKFYLDRC
IYCGQCVDSCPKDALELTPDFELAQIDKEKLRVVCRREEGEDKPEEPS
>Mature_128_residues
MKIPGKMAHEVLRHSVMKPATCNYPAEKQKMPEHFRGRIRYKAEKCIGCKFCVRDCPARAIEIFKVADKVFEAKFYLDRC
IYCGQCVDSCPKDALELTPDFELAQIDKEKLRVVCRREEGEDKPEEPS

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=111, Percent_Identity=38.7387387387387, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789075, Length=91, Percent_Identity=37.3626373626374, Blast_Score=70, Evalue=6e-14,
Organism=Escherichia coli, GI1788617, Length=110, Percent_Identity=33.6363636363636, Blast_Score=68, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555194, Length=111, Percent_Identity=37.8378378378378, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17864306, Length=111, Percent_Identity=39.6396396396396, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR004497
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 14830; Mature: 14830

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
10.9 %Cys+Met (Translated Protein)
7.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
10.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPGKMAHEVLRHSVMKPATCNYPAEKQKMPEHFRGRIRYKAEKCIGCKFCVRDCPARA
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IEIFKVADKVFEAKFYLDRCIYCGQCVDSCPKDALELTPDFELAQIDKEKLRVVCRREEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHCHHHHHHHHHHCCC
EDKPEEPS
CCCCCCCC
>Mature Secondary Structure
MKIPGKMAHEVLRHSVMKPATCNYPAEKQKMPEHFRGRIRYKAEKCIGCKFCVRDCPARA
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IEIFKVADKVFEAKFYLDRCIYCGQCVDSCPKDALELTPDFELAQIDKEKLRVVCRREEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHCHHHHHHHHHHCCC
EDKPEEPS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; Proton; reduced ferredoxin [C]

Specific reaction: formate = CO2 + H2 Proton + reduced ferredoxin = H2 + oxidized ferredoxin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA