Click here to switch to the map view.

The map label for this gene is nuoH [H]

Identifier: 118581923

GI number: 118581923

Start: 3895333

End: 3896274

Strand: Reverse

Name: nuoH [H]

Synonym: Ppro_3523

Alternate gene names: 118581923

Gene position: 3896274-3895333 (Counterclockwise)

Preceding gene: 118581924

Following gene: 118581922

Centisome position: 97.21

GC content: 60.51

Gene sequence:

>942_bases
ATGACACAGGCACTCTTCAATCTTCTGATATTCCCCGGTTTTCTCTTCCTCAGCCTGGCCGGGATGGTGGCGGAATTCTG
CGACAGGAAGTTGTACGCCCGCATGCAGAACAGGCAGGGGCCTCCCTGGTTCCAGCCCTTTGCCGACTTCATCAAGCTCT
CCTCCAAGGAGGACATCATACCGGAGGAGGCCGACCCGTTCATGTTCAGGCTGATGCCACTGGTGGCGCTGGCCGCCTCG
GTATGCGCCATCCTCTACATCCCCATCTGGGGAAGGGGGGCGCTGCTCTCCTTCGAGGGGGATCTGGTGATCGTAGTCTA
CCTGCTGACCATCCCCACCATGACCTTCTTCCTGGCCGGGTGGTATTCGGCCTCGCTCTACTCCATGATCGGCGCGGTCC
GCTCCCTGACCCAGCTTTTGGCATACGAGGTGCCGCTCTACCTGGCGCTGCTGGCGCCGGCCTGTCTGGCCGACAGCTGG
TCCCTGGCCGGTATGGCCGCCTACTATGGCGCCCACCCCTGGCGCTGGCTGTTGAACCTGATCGGTTTTGGCGTAGGGCT
GGTGGTGATGCTGGGTAAACTGGAGAAGGTCCCCTTCGACACCCCCGAGGCTGAAACCGAGATCGTTGCCGGTGCCTTCA
CCGAGTACAGCGGCCGTCTGCTGGCCCTGTTTCGGATGGCCATCAGCATTGAAATGATAGTTCTGGCCTCCCTGCTGGCG
GCGGTATTCCTTCCCTTTGGGCTTGGTCTGGGACCCCTGGCCGGTTTCCTGCTCTACCTGCTGAAGATAGCCCTGATCAT
CGCCATGACCAGCTTTTTGCGGACCATCTTCGCTCGCTTCCGAATCGACCAGATGGTGGATTTCTGCTGGCGTTACGTGG
CTTCGGCTGCCATGCTCCAGCTTGTGATCGTCATCATTGCCAAGGGGGTGTTGCCGCAATGA

Upstream 100 bases:

>100_bases
AGCTGCGCCGTCGGGGCGTGGAATGGTACCGCCGCAACCGGGGGATCGATTTCAGCGGCCCGAGCCGCAGGCTGCAGATG
CTGCGTGGAGACAGACGGCC

Downstream 100 bases:

>100_bases
AGATACCGGGGAAGATGGCACACGAGGTGCTGCGGCACTCGGTAATGAAACCGGCCACCTGCAACTATCCGGCTGAGAAG
CAGAAGATGCCGGAGCATTT

Product: respiratory-chain NADH dehydrogenase, subunit 1

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTQALFNLLIFPGFLFLSLAGMVAEFCDRKLYARMQNRQGPPWFQPFADFIKLSSKEDIIPEEADPFMFRLMPLVALAAS
VCAILYIPIWGRGALLSFEGDLVIVVYLLTIPTMTFFLAGWYSASLYSMIGAVRSLTQLLAYEVPLYLALLAPACLADSW
SLAGMAAYYGAHPWRWLLNLIGFGVGLVVMLGKLEKVPFDTPEAETEIVAGAFTEYSGRLLALFRMAISIEMIVLASLLA
AVFLPFGLGLGPLAGFLLYLLKIALIIAMTSFLRTIFARFRIDQMVDFCWRYVASAAMLQLVIVIIAKGVLPQ

Sequences:

>Translated_313_residues
MTQALFNLLIFPGFLFLSLAGMVAEFCDRKLYARMQNRQGPPWFQPFADFIKLSSKEDIIPEEADPFMFRLMPLVALAAS
VCAILYIPIWGRGALLSFEGDLVIVVYLLTIPTMTFFLAGWYSASLYSMIGAVRSLTQLLAYEVPLYLALLAPACLADSW
SLAGMAAYYGAHPWRWLLNLIGFGVGLVVMLGKLEKVPFDTPEAETEIVAGAFTEYSGRLLALFRMAISIEMIVLASLLA
AVFLPFGLGLGPLAGFLLYLLKIALIIAMTSFLRTIFARFRIDQMVDFCWRYVASAAMLQLVIVIIAKGVLPQ
>Mature_312_residues
TQALFNLLIFPGFLFLSLAGMVAEFCDRKLYARMQNRQGPPWFQPFADFIKLSSKEDIIPEEADPFMFRLMPLVALAASV
CAILYIPIWGRGALLSFEGDLVIVVYLLTIPTMTFFLAGWYSASLYSMIGAVRSLTQLLAYEVPLYLALLAPACLADSWS
LAGMAAYYGAHPWRWLLNLIGFGVGLVVMLGKLEKVPFDTPEAETEIVAGAFTEYSGRLLALFRMAISIEMIVLASLLAA
VFLPFGLGLGPLAGFLLYLLKIALIIAMTSFLRTIFARFRIDQMVDFCWRYVASAAMLQLVIVIIAKGVLPQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=272, Percent_Identity=28.3088235294118, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788618, Length=291, Percent_Identity=29.8969072164948, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082115, Length=224, Percent_Identity=32.5892857142857, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789077, Length=271, Percent_Identity=29.1512915129151, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 34687; Mature: 34556

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQALFNLLIFPGFLFLSLAGMVAEFCDRKLYARMQNRQGPPWFQPFADFIKLSSKEDII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
PEEADPFMFRLMPLVALAASVCAILYIPIWGRGALLSFEGDLVIVVYLLTIPTMTFFLAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
WYSASLYSMIGAVRSLTQLLAYEVPLYLALLAPACLADSWSLAGMAAYYGAHPWRWLLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHH
IGFGVGLVVMLGKLEKVPFDTPEAETEIVAGAFTEYSGRLLALFRMAISIEMIVLASLLA
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVFLPFGLGLGPLAGFLLYLLKIALIIAMTSFLRTIFARFRIDQMVDFCWRYVASAAMLQ
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVIVIIAKGVLPQ
HHHHHHHHCCCCC
>Mature Secondary Structure 
TQALFNLLIFPGFLFLSLAGMVAEFCDRKLYARMQNRQGPPWFQPFADFIKLSSKEDII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
PEEADPFMFRLMPLVALAASVCAILYIPIWGRGALLSFEGDLVIVVYLLTIPTMTFFLAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
WYSASLYSMIGAVRSLTQLLAYEVPLYLALLAPACLADSWSLAGMAAYYGAHPWRWLLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHH
IGFGVGLVVMLGKLEKVPFDTPEAETEIVAGAFTEYSGRLLALFRMAISIEMIVLASLLA
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVFLPFGLGLGPLAGFLLYLLKIALIIAMTSFLRTIFARFRIDQMVDFCWRYVASAAMLQ
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVIVIIAKGVLPQ
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA