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The map label for this gene is metX

Identifier: 118581900

GI number: 118581900

Start: 3868705

End: 3869820

Strand: Reverse

Name: metX

Synonym: Ppro_3500

Alternate gene names: 118581900

Gene position: 3869820-3868705 (Counterclockwise)

Preceding gene: 118581902

Following gene: 118581899

Centisome position: 96.55

GC content: 61.74

Gene sequence:

>1116_bases
ATGTCCGTCAGCATCGTAAGGGAACAGTCCATAACCATCAGTGACGGCATCAGGCTGGATAGCGGACGAATCCTGGCCCC
CATCACCATTGCCTACGAGACCTACGGAACCCTCAACACCGACGCATCCAATGCCATCCTGGTGGAACACGCCTGGACCG
GCAGCGCCCACCTGGCCGGAAAACAGAGCGAGAACGATACCAAGCCGGGGTGGTGGGATGCCATCGTAGGTCCCGGCCGA
CTGCTGGACACCGACCGCTACTTCGTGATCTGCTCCAACGTGATCGGTTCTTGTTTCGGCTCCACCGGCCCCGCCTCCAT
CAACCCCAAGACCGGAAAACGATACAACCTGACCTTTCCGGTGATCACCATCCGGGACATGGTGCGCGCCCAGAAGCTGC
TGATCGAGATGCTGGGCATCCGGCGACTGCTCTCCGTCATGGGGGGGAGCATGGGCGGCATGCAGACTCTGGAGTGGATC
ACCCAGTATCCGGACGCCATCGCTTCGGCCGTCCTGCTGGCCACCACCCCCCGCCCCTCGCCTTTGGCCATCTCCATGAA
CGCCATCGCCCGCTGGTCCATCTTCAACGACCCCACCTGGCGCAAGGGGGAGTACAAGAACAACCCCAAGGACGGTCTGG
CGCTGGCCCGCGCCATCGGGCACATCACCTTCCTGTCCGACGAATCCATGCAGGCCAAGTTCGGCCGCAAATTCTCTGCC
CGTGACGGCCAGTTCGACTTCTTCGGCCAGTTCGAGGTGGAGCGCTATCTGGACTACAACGGCTACAGCTTTGTCAGCCG
TTTCGACGCCAACTCCTTCCTCTACCTGGCCAAGGCACTGGACCTGTACGATGTCTCCTGGGGCTACGAATCCATGGCCG
AGGCCTTTGCCAGGGTCAGCGCTCCGCTGCAGTTCTTCGCCTTTTCCTCCGACTGGCTCTATCCTCCCGGCCAGACCGAG
GAGATGGTCAGCTGTCTGCGGAAACTGGGCAAGGAGGTGGAGTACCACCTGATCAGTTCCTCCTACGGCCACGACGCCTT
CCTGCTGGAACACGAGGCGTTCTCCCCCCTGGTGAAGCGGTTCCTGGATGCTGCGTACGCCAAAGGCGGCCAGTGA

Upstream 100 bases:

>100_bases
ATGGCGCCAGGTGCTAATTCCTGCCGTCAGGCAAAGATGAGAGGGTGTGCTGTGATCGTGTCGTAACAGCCCCTTTTCAT
TTCCGTGAAGGGGTTTTCTC

Downstream 100 bases:

>100_bases
CCCTATGACCTTGACGCAGCAGGAGATGCGTGAGTTGCCGCTGTTCAGGCGGCTGCGCCATGCCGTGGGAAAAGCGGTGG
CTGATTTCGCCATGATCCGT

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSVSIVREQSITISDGIRLDSGRILAPITIAYETYGTLNTDASNAILVEHAWTGSAHLAGKQSENDTKPGWWDAIVGPGR
LLDTDRYFVICSNVIGSCFGSTGPASINPKTGKRYNLTFPVITIRDMVRAQKLLIEMLGIRRLLSVMGGSMGGMQTLEWI
TQYPDAIASAVLLATTPRPSPLAISMNAIARWSIFNDPTWRKGEYKNNPKDGLALARAIGHITFLSDESMQAKFGRKFSA
RDGQFDFFGQFEVERYLDYNGYSFVSRFDANSFLYLAKALDLYDVSWGYESMAEAFARVSAPLQFFAFSSDWLYPPGQTE
EMVSCLRKLGKEVEYHLISSSYGHDAFLLEHEAFSPLVKRFLDAAYAKGGQ

Sequences:

>Translated_371_residues
MSVSIVREQSITISDGIRLDSGRILAPITIAYETYGTLNTDASNAILVEHAWTGSAHLAGKQSENDTKPGWWDAIVGPGR
LLDTDRYFVICSNVIGSCFGSTGPASINPKTGKRYNLTFPVITIRDMVRAQKLLIEMLGIRRLLSVMGGSMGGMQTLEWI
TQYPDAIASAVLLATTPRPSPLAISMNAIARWSIFNDPTWRKGEYKNNPKDGLALARAIGHITFLSDESMQAKFGRKFSA
RDGQFDFFGQFEVERYLDYNGYSFVSRFDANSFLYLAKALDLYDVSWGYESMAEAFARVSAPLQFFAFSSDWLYPPGQTE
EMVSCLRKLGKEVEYHLISSSYGHDAFLLEHEAFSPLVKRFLDAAYAKGGQ
>Mature_370_residues
SVSIVREQSITISDGIRLDSGRILAPITIAYETYGTLNTDASNAILVEHAWTGSAHLAGKQSENDTKPGWWDAIVGPGRL
LDTDRYFVICSNVIGSCFGSTGPASINPKTGKRYNLTFPVITIRDMVRAQKLLIEMLGIRRLLSVMGGSMGGMQTLEWIT
QYPDAIASAVLLATTPRPSPLAISMNAIARWSIFNDPTWRKGEYKNNPKDGLALARAIGHITFLSDESMQAKFGRKFSAR
DGQFDFFGQFEVERYLDYNGYSFVSRFDANSFLYLAKALDLYDVSWGYESMAEAFARVSAPLQFFAFSSDWLYPPGQTEE
MVSCLRKLGKEVEYHLISSSYGHDAFLLEHEAFSPLVKRFLDAAYAKGGQ

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=238, Percent_Identity=37.3949579831933, Blast_Score=162, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_PELPD (A1AUS2)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_903150.1
- ProteinModelPortal:   A1AUS2
- SMR:   A1AUS2
- STRING:   A1AUS2
- GeneID:   4574349
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3500
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   A1AUS2
- ProtClustDB:   CLSK828845
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 41259; Mature: 41128

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 150-150 ACT_SITE 344-344

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSIVREQSITISDGIRLDSGRILAPITIAYETYGTLNTDASNAILVEHAWTGSAHLAG
CCCEEEECCCEEEECCEEECCCCEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCCEECC
KQSENDTKPGWWDAIVGPGRLLDTDRYFVICSNVIGSCFGSTGPASINPKTGKRYNLTFP
CCCCCCCCCCCCHHCCCCCCEECCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
VITIRDMVRAQKLLIEMLGIRRLLSVMGGSMGGMQTLEWITQYPDAIASAVLLATTPRPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHEEEEEECCCCC
PLAISMNAIARWSIFNDPTWRKGEYKNNPKDGLALARAIGHITFLSDESMQAKFGRKFSA
CEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHCCCCCC
RDGQFDFFGQFEVERYLDYNGYSFVSRFDANSFLYLAKALDLYDVSWGYESMAEAFARVS
CCCCEEEEECEEEEEEECCCCCHHHHHCCCCCEEEHHHHHHHEECCCCHHHHHHHHHHHC
APLQFFAFSSDWLYPPGQTEEMVSCLRKLGKEVEYHLISSSYGHDAFLLEHEAFSPLVKR
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEHHHHHHHHHH
FLDAAYAKGGQ
HHHHHHHCCCC
>Mature Secondary Structure 
SVSIVREQSITISDGIRLDSGRILAPITIAYETYGTLNTDASNAILVEHAWTGSAHLAG
CCEEEECCCEEEECCEEECCCCEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCCEECC
KQSENDTKPGWWDAIVGPGRLLDTDRYFVICSNVIGSCFGSTGPASINPKTGKRYNLTFP
CCCCCCCCCCCCHHCCCCCCEECCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
VITIRDMVRAQKLLIEMLGIRRLLSVMGGSMGGMQTLEWITQYPDAIASAVLLATTPRPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHEEEEEECCCCC
PLAISMNAIARWSIFNDPTWRKGEYKNNPKDGLALARAIGHITFLSDESMQAKFGRKFSA
CEEEECCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHCCCCCC
RDGQFDFFGQFEVERYLDYNGYSFVSRFDANSFLYLAKALDLYDVSWGYESMAEAFARVS
CCCCEEEEECEEEEEEECCCCCHHHHHCCCCCEEEHHHHHHHEECCCCHHHHHHHHHHHC
APLQFFAFSSDWLYPPGQTEEMVSCLRKLGKEVEYHLISSSYGHDAFLLEHEAFSPLVKR
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEHHHHHHHHHH
FLDAAYAKGGQ
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA