Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 118581894

GI number: 118581894

Start: 3859698

End: 3861887

Strand: Direct

Name: yciR [C]

Synonym: Ppro_3494

Alternate gene names: 118581894

Gene position: 3859698-3861887 (Clockwise)

Preceding gene: 118581893

Following gene: 118581895

Centisome position: 96.3

GC content: 59.13

Gene sequence:

>2190_bases
TTGAATACCGGCCACATTTCCATACAGCAGTTTACCCAGGCCATGGCCTGGACTCTCTCGGCGATGATCACACTCCTGGC
GCCGGCCACCTTTTTCCTGGTCTCCTGCGAGCACCTGCGAAGCGAACTCCACGTCCAGACCGAATTGAGCGCTAACGACC
TGAGTGCTATGATCAGCTCCAATACGCAGTTGTGGAGGTATGAGGAGCTCAGGCTTTCGGAACTGCTACGGCGGCGGTCG
AACAGTGTTGTTGCCGAGAGCAGAATCCTCTACGACATCGGCGGCGAAGTCATCGCCAGAAATCGGCAACAGGTGTCCAT
TCCCCGTATCACGGACGTGCATGACATCTTTGATGCCGGAACTGCTGTTGCCCGCATCGAGGCTTCCCGTTCCCTAACCC
CCCTGCTGCTCAGAACGTTCGCCGTGGCGCTCTGTTCGGCGATAATCGCCGCAGTAGTGTTTTACATGCTGCGTACGCTT
CCCCTGCGCGCCACATCCAGGGCCTATCAGGCCTTGGACGAAAGTGAGAGCAAATACCGTCTGCTGTACGAAAGCATGCG
GGAGGGGATGGCGCTGCACCACATGGATTTCGACGAAAACGGTGATTTTGCTGCCATCTCGGTTATCGACGCGAATCCGA
GCTGCGCGGCCATGTTCGGCTGTGATCCGCAGACGCTCATCGGCAGCGACAGTATCGCGCTGTTTGGGGAAACCTTCCGG
GAGTACCTCTCGGAGTTGCTGCGACTGCTGGAACAGGGCACCAGCATCCAGTTCGAGCTGACCCTGCCGCGCACGGACAA
CCTTTACAGCGTACACGCCTTTTCTCCCGACCACGGCTTGGTCGCCACACTGTTCGAGGATATTACCGAGCGCAGGAAAT
CCGAGCAGCAGATCCAGCACATGGCCTACTTCGACAGCCTCACCGATCTTCCCAACCGGGTCCTGTTTCTTGACCGCCTC
CGGCAGGCCATAGCCCATGCACTTCGGGATGAGAATTCCCTGGCGGTGCTGTTCCTCGACCTGGACCGGTTCAAGGATAT
CAACGACACCCTGGGACATTCGGCAGGGGACCAGCTGCTGATCCAGGTCACCCGGCGCCTGGGGCGGCAGATCCGTTCCT
GTGACACCCTGGCCCGCCTGGGAGGGGACGAGTTCGTGGTCATCGTCACCGATCTGGGTAAAAAAATGAACGCCACCCGG
GTTGCCCAGGACCTTATCAATGCGATCCAGCCCCCCTTCCTGATCGCCGGACGCGAGCTGCACGTGACCACCAGCATCGG
TATCGCGCTCTTCCCCGACGATGGCAATAACGCGGAAACGCTCGTCAAGCACGCCGATCTGGCAATGTATTCATCCAAGG
AGTCGGGGCGCAACAGGTACAACTTCTACTCCGCCTCCATGAACCAGAAGGCGCTCATGCGCATGGAGACCGAGGCCGGC
CTGCGCAACGCGCTGGAACGGAGAGAATTTTATGTGGAATTTCAGCCCATCATGAATGCAGCTGACTCTACCGTTGTGGC
TGCCGAAGCACTCGTGCGCTGGAACCACCCCACCCGCGGCAGGATTCCGCCAGACCAGTTCATCGACCTGGCCGAAGAAA
CCGGTCTGGTCGTTCCCCTGGGGGAATGGGTGCTGCGCACCGTCTGCTCGAGGATAAAAACGTGGAGCGATGCCGGACTC
CCGCTGATCAGGTTTTCGGTCAATGTCTCCAGCAGGCAGATCGAGCGGCAGGACTTCGCGGAAATCGTCAGGAACGCGCT
GCGCGAATCGGGCGCCAACAGCGCCCAACTGGAGATCGAACTTACCGAGAGCTGCCTGATCCGACACTCGGACACGAACA
TCAGCGATCTCTTCGGACTGAAGGAGTGGGGCGTTTCCTTCGCCATCGACGACTTCGGCACCGGCTATTCATCCCTGGGA
TATATCAAGACCCTGCCCATCGACCATATCAAAATCGACCGGTCGTTTGTCAGGGACATCAGCACGGACTTCCACGACCA
GGCCATTGTGGAGGCGATCATCGCCATGTCGCAAAGGCTGGGCATCCGCAATATCGCCGAGGGGGTGGAGACCATCGAAC
AGGTCCGTTTCCTTCAGGAGCGTGGCTGCGAAGAGATCCAGGGGTACTACTTCCACCGCCCCCTGTCGGCTGAGGCGCTG
GAGGAACTGCTCAGAGCCCAAGAAAACTAG

Upstream 100 bases:

>100_bases
AGAGATTGATCGACTTCATCTTCTCACCCCAGGGGCGTGCCATAGCACAGAAAAACGGTGTGCTCGTCCTCCCCAGACCC
GTGCCGAACAACTAACACCA

Downstream 100 bases:

>100_bases
GCATAGGCGCCGGGCATTGGGGCTTCCGGTGCCTCGCTACGGGCTGGTTGATTTCCACATCTGGTCACCGGTTACATGGT
ACGGAATGGAGCGTATGGAA

Product: PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MNTGHISIQQFTQAMAWTLSAMITLLAPATFFLVSCEHLRSELHVQTELSANDLSAMISSNTQLWRYEELRLSELLRRRS
NSVVAESRILYDIGGEVIARNRQQVSIPRITDVHDIFDAGTAVARIEASRSLTPLLLRTFAVALCSAIIAAVVFYMLRTL
PLRATSRAYQALDESESKYRLLYESMREGMALHHMDFDENGDFAAISVIDANPSCAAMFGCDPQTLIGSDSIALFGETFR
EYLSELLRLLEQGTSIQFELTLPRTDNLYSVHAFSPDHGLVATLFEDITERRKSEQQIQHMAYFDSLTDLPNRVLFLDRL
RQAIAHALRDENSLAVLFLDLDRFKDINDTLGHSAGDQLLIQVTRRLGRQIRSCDTLARLGGDEFVVIVTDLGKKMNATR
VAQDLINAIQPPFLIAGRELHVTTSIGIALFPDDGNNAETLVKHADLAMYSSKESGRNRYNFYSASMNQKALMRMETEAG
LRNALERREFYVEFQPIMNAADSTVVAAEALVRWNHPTRGRIPPDQFIDLAEETGLVVPLGEWVLRTVCSRIKTWSDAGL
PLIRFSVNVSSRQIERQDFAEIVRNALRESGANSAQLEIELTESCLIRHSDTNISDLFGLKEWGVSFAIDDFGTGYSSLG
YIKTLPIDHIKIDRSFVRDISTDFHDQAIVEAIIAMSQRLGIRNIAEGVETIEQVRFLQERGCEEIQGYYFHRPLSAEAL
EELLRAQEN

Sequences:

>Translated_729_residues
MNTGHISIQQFTQAMAWTLSAMITLLAPATFFLVSCEHLRSELHVQTELSANDLSAMISSNTQLWRYEELRLSELLRRRS
NSVVAESRILYDIGGEVIARNRQQVSIPRITDVHDIFDAGTAVARIEASRSLTPLLLRTFAVALCSAIIAAVVFYMLRTL
PLRATSRAYQALDESESKYRLLYESMREGMALHHMDFDENGDFAAISVIDANPSCAAMFGCDPQTLIGSDSIALFGETFR
EYLSELLRLLEQGTSIQFELTLPRTDNLYSVHAFSPDHGLVATLFEDITERRKSEQQIQHMAYFDSLTDLPNRVLFLDRL
RQAIAHALRDENSLAVLFLDLDRFKDINDTLGHSAGDQLLIQVTRRLGRQIRSCDTLARLGGDEFVVIVTDLGKKMNATR
VAQDLINAIQPPFLIAGRELHVTTSIGIALFPDDGNNAETLVKHADLAMYSSKESGRNRYNFYSASMNQKALMRMETEAG
LRNALERREFYVEFQPIMNAADSTVVAAEALVRWNHPTRGRIPPDQFIDLAEETGLVVPLGEWVLRTVCSRIKTWSDAGL
PLIRFSVNVSSRQIERQDFAEIVRNALRESGANSAQLEIELTESCLIRHSDTNISDLFGLKEWGVSFAIDDFGTGYSSLG
YIKTLPIDHIKIDRSFVRDISTDFHDQAIVEAIIAMSQRLGIRNIAEGVETIEQVRFLQERGCEEIQGYYFHRPLSAEAL
EELLRAQEN
>Mature_729_residues
MNTGHISIQQFTQAMAWTLSAMITLLAPATFFLVSCEHLRSELHVQTELSANDLSAMISSNTQLWRYEELRLSELLRRRS
NSVVAESRILYDIGGEVIARNRQQVSIPRITDVHDIFDAGTAVARIEASRSLTPLLLRTFAVALCSAIIAAVVFYMLRTL
PLRATSRAYQALDESESKYRLLYESMREGMALHHMDFDENGDFAAISVIDANPSCAAMFGCDPQTLIGSDSIALFGETFR
EYLSELLRLLEQGTSIQFELTLPRTDNLYSVHAFSPDHGLVATLFEDITERRKSEQQIQHMAYFDSLTDLPNRVLFLDRL
RQAIAHALRDENSLAVLFLDLDRFKDINDTLGHSAGDQLLIQVTRRLGRQIRSCDTLARLGGDEFVVIVTDLGKKMNATR
VAQDLINAIQPPFLIAGRELHVTTSIGIALFPDDGNNAETLVKHADLAMYSSKESGRNRYNFYSASMNQKALMRMETEAG
LRNALERREFYVEFQPIMNAADSTVVAAEALVRWNHPTRGRIPPDQFIDLAEETGLVVPLGEWVLRTVCSRIKTWSDAGL
PLIRFSVNVSSRQIERQDFAEIVRNALRESGANSAQLEIELTESCLIRHSDTNISDLFGLKEWGVSFAIDDFGTGYSSLG
YIKTLPIDHIKIDRSFVRDISTDFHDQAIVEAIIAMSQRLGIRNIAEGVETIEQVRFLQERGCEEIQGYYFHRPLSAEAL
EELLRAQEN

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=439, Percent_Identity=39.4077448747153, Blast_Score=326, Evalue=3e-90,
Organism=Escherichia coli, GI87081921, Length=431, Percent_Identity=33.6426914153132, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI226510982, Length=442, Percent_Identity=30.0904977375566, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1788502, Length=255, Percent_Identity=34.1176470588235, Blast_Score=170, Evalue=4e-43,
Organism=Escherichia coli, GI1786507, Length=270, Percent_Identity=31.8518518518519, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=32.8, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI87081743, Length=238, Percent_Identity=33.1932773109244, Blast_Score=136, Evalue=6e-33,
Organism=Escherichia coli, GI87081980, Length=243, Percent_Identity=34.5679012345679, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1790496, Length=248, Percent_Identity=30.241935483871, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1787055, Length=391, Percent_Identity=25.0639386189258, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788381, Length=306, Percent_Identity=30.718954248366, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1788849, Length=436, Percent_Identity=27.0642201834862, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI145693134, Length=193, Percent_Identity=35.2331606217617, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=34.9397590361446, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786584, Length=177, Percent_Identity=30.5084745762712, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87082096, Length=235, Percent_Identity=28.936170212766, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87081881, Length=261, Percent_Identity=28.3524904214559, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081977, Length=180, Percent_Identity=30, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788956, Length=185, Percent_Identity=32.972972972973, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787802, Length=172, Percent_Identity=31.3953488372093, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=30.952380952381, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=31.9018404907975, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1787056, Length=166, Percent_Identity=32.5301204819277, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787410, Length=226, Percent_Identity=27.4336283185841, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081974, Length=87, Percent_Identity=36.7816091954023, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=27.4390243902439, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 82100; Mature: 82100

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTGHISIQQFTQAMAWTLSAMITLLAPATFFLVSCEHLRSELHVQTELSANDLSAMISS
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHC
NTQLWRYEELRLSELLRRRSNSVVAESRILYDIGGEVIARNRQQVSIPRITDVHDIFDAG
CCCEEEHHHHHHHHHHHHHCCCHHHHHHEEEECCCHHHHCCCCEECCCCCCCHHHHHHCC
TAVARIEASRSLTPLLLRTFAVALCSAIIAAVVFYMLRTLPLRATSRAYQALDESESKYR
CHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
LLYESMREGMALHHMDFDENGDFAAISVIDANPSCAAMFGCDPQTLIGSDSIALFGETFR
HHHHHHHCCCEEEECCCCCCCCEEEEEEEECCCCEEEEECCCCCCEECCCCHHHHHHHHH
EYLSELLRLLEQGTSIQFELTLPRTDNLYSVHAFSPDHGLVATLFEDITERRKSEQQIQH
HHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
MAYFDSLTDLPNRVLFLDRLRQAIAHALRDENSLAVLFLDLDRFKDINDTLGHSAGDQLL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCHHHHCCCCCHHHH
IQVTRRLGRQIRSCDTLARLGGDEFVVIVTDLGKKMNATRVAQDLINAIQPPFLIAGREL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCEE
HVTTSIGIALFPDDGNNAETLVKHADLAMYSSKESGRNRYNFYSASMNQKALMRMETEAG
EEEEECCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
LRNALERREFYVEFQPIMNAADSTVVAAEALVRWNHPTRGRIPPDQFIDLAEETGLVVPL
HHHHHHHHHHEEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEH
GEWVLRTVCSRIKTWSDAGLPLIRFSVNVSSRQIERQDFAEIVRNALRESGANSAQLEIE
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LTESCLIRHSDTNISDLFGLKEWGVSFAIDDFGTGYSSLGYIKTLPIDHIKIDRSFVRDI
ECHHHHEECCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCEEECCCCCEEHHHHHHHHH
STDFHDQAIVEAIIAMSQRLGIRNIAEGVETIEQVRFLQERGCEEIQGYYFHRPLSAEAL
HCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHCCEEECCCCCHHHH
EELLRAQEN
HHHHHHCCC
>Mature Secondary Structure
MNTGHISIQQFTQAMAWTLSAMITLLAPATFFLVSCEHLRSELHVQTELSANDLSAMISS
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHC
NTQLWRYEELRLSELLRRRSNSVVAESRILYDIGGEVIARNRQQVSIPRITDVHDIFDAG
CCCEEEHHHHHHHHHHHHHCCCHHHHHHEEEECCCHHHHCCCCEECCCCCCCHHHHHHCC
TAVARIEASRSLTPLLLRTFAVALCSAIIAAVVFYMLRTLPLRATSRAYQALDESESKYR
CHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
LLYESMREGMALHHMDFDENGDFAAISVIDANPSCAAMFGCDPQTLIGSDSIALFGETFR
HHHHHHHCCCEEEECCCCCCCCEEEEEEEECCCCEEEEECCCCCCEECCCCHHHHHHHHH
EYLSELLRLLEQGTSIQFELTLPRTDNLYSVHAFSPDHGLVATLFEDITERRKSEQQIQH
HHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
MAYFDSLTDLPNRVLFLDRLRQAIAHALRDENSLAVLFLDLDRFKDINDTLGHSAGDQLL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCHHHHCCCCCHHHH
IQVTRRLGRQIRSCDTLARLGGDEFVVIVTDLGKKMNATRVAQDLINAIQPPFLIAGREL
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCEE
HVTTSIGIALFPDDGNNAETLVKHADLAMYSSKESGRNRYNFYSASMNQKALMRMETEAG
EEEEECCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
LRNALERREFYVEFQPIMNAADSTVVAAEALVRWNHPTRGRIPPDQFIDLAEETGLVVPL
HHHHHHHHHHEEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEH
GEWVLRTVCSRIKTWSDAGLPLIRFSVNVSSRQIERQDFAEIVRNALRESGANSAQLEIE
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LTESCLIRHSDTNISDLFGLKEWGVSFAIDDFGTGYSSLGYIKTLPIDHIKIDRSFVRDI
ECHHHHEECCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCEEECCCCCEEHHHHHHHHH
STDFHDQAIVEAIIAMSQRLGIRNIAEGVETIEQVRFLQERGCEEIQGYYFHRPLSAEAL
HCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHCCEEECCCCCHHHH
EELLRAQEN
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]