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The map label for this gene is rfbC [H]

Identifier: 118581747

GI number: 118581747

Start: 3694999

End: 3695562

Strand: Reverse

Name: rfbC [H]

Synonym: Ppro_3347

Alternate gene names: 118581747

Gene position: 3695562-3694999 (Counterclockwise)

Preceding gene: 118581748

Following gene: 118581746

Centisome position: 92.2

GC content: 51.95

Gene sequence:

>564_bases
ATGACTTTTATACATACAAGAATTTCAGGTTGCCTCGAGATCGTTCCTGTTTGTTTCCAGGACGAACGTGGCAGGTTCGT
CAAAACCTACAACGAAAAAACGTTCGAGTCGCACGGCTGTTGCACCGACTGGAAAGAAGAATTCTACTCAGTTTCCAGGC
GGGGAGTGCTTCGAGGGTTGCACTTCCAACTCCCCCCCCATCAGCACGACAAGTTGGTATACTGCACCGCGGGCACGGTA
CTGGATGCGGTCGTGGACCTACGAAAAGGCTCTCCCACATATGGGGATCATATTATGCTCGAACTGAGTGCCGAAAAAGG
AAACATGCTCTACATCCCCCGGGGGCTCGCCCATGGGTTTTACGTCACCAGCGAGTCAGCCACAATGATGTACAAGGTTT
CTTCTGTCTACGCTCCTGACCATGATGCCGGAATCCGCTGGGACTCTGCCGGAATTGCCTGGCCCGCCAGCACGCCGATC
ATATCCACAAAGGATGGCCTCCTCCCGCCTCTTATTGACTTTTCATCTCCTTTTTCCTTTGACGATTGTGCGAAAAGACA
ATGA

Upstream 100 bases:

>100_bases
GCGATACATTTTGGATTGGGGTCTATCCGGGTATGACAGAGGAAATGATTGCGTATATGCTTGATACCATCCGGGCATTC
ATCAAGCGTGGCGGATCGAC

Downstream 100 bases:

>100_bases
AGATACTCCTGACCGGCGCAACCGGTTTCGTGGGAAGCCATGTAATCCGCCGCCTCATTGAGAGGGGGCACAATGTCACT
GTTGTCGTCCGCGATCAGAC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MTFIHTRISGCLEIVPVCFQDERGRFVKTYNEKTFESHGCCTDWKEEFYSVSRRGVLRGLHFQLPPHQHDKLVYCTAGTV
LDAVVDLRKGSPTYGDHIMLELSAEKGNMLYIPRGLAHGFYVTSESATMMYKVSSVYAPDHDAGIRWDSAGIAWPASTPI
ISTKDGLLPPLIDFSSPFSFDDCAKRQ

Sequences:

>Translated_187_residues
MTFIHTRISGCLEIVPVCFQDERGRFVKTYNEKTFESHGCCTDWKEEFYSVSRRGVLRGLHFQLPPHQHDKLVYCTAGTV
LDAVVDLRKGSPTYGDHIMLELSAEKGNMLYIPRGLAHGFYVTSESATMMYKVSSVYAPDHDAGIRWDSAGIAWPASTPI
ISTKDGLLPPLIDFSSPFSFDDCAKRQ
>Mature_186_residues
TFIHTRISGCLEIVPVCFQDERGRFVKTYNEKTFESHGCCTDWKEEFYSVSRRGVLRGLHFQLPPHQHDKLVYCTAGTVL
DAVVDLRKGSPTYGDHIMLELSAEKGNMLYIPRGLAHGFYVTSESATMMYKVSSVYAPDHDAGIRWDSAGIAWPASTPII
STKDGLLPPLIDFSSPFSFDDCAKRQ

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=175, Percent_Identity=40.5714285714286, Blast_Score=125, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17550412, Length=165, Percent_Identity=39.3939393939394, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21001; Mature: 20870

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFIHTRISGCLEIVPVCFQDERGRFVKTYNEKTFESHGCCTDWKEEFYSVSRRGVLRGL
CEEEHHHHHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
HFQLPPHQHDKLVYCTAGTVLDAVVDLRKGSPTYGDHIMLELSAEKGNMLYIPRGLAHGF
EEECCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCCE
YVTSESATMMYKVSSVYAPDHDAGIRWDSAGIAWPASTPIISTKDGLLPPLIDFSSPFSF
EEECCCCEEEEEEEEEECCCCCCCEEECCCCEECCCCCCEEECCCCCCCCCCCCCCCCCC
DDCAKRQ
CHHCCCC
>Mature Secondary Structure 
TFIHTRISGCLEIVPVCFQDERGRFVKTYNEKTFESHGCCTDWKEEFYSVSRRGVLRGL
EEEHHHHHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
HFQLPPHQHDKLVYCTAGTVLDAVVDLRKGSPTYGDHIMLELSAEKGNMLYIPRGLAHGF
EEECCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCCE
YVTSESATMMYKVSSVYAPDHDAGIRWDSAGIAWPASTPIISTKDGLLPPLIDFSSPFSF
EEECCCCEEEEEEEEEECCCCCCCEEECCCCEECCCCCCEEECCCCCCCCCCCCCCCCCC
DDCAKRQ
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8170390; 8157605; 12384590; 12704152 [H]