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The map label for this gene is trxB [H]

Identifier: 118581728

GI number: 118581728

Start: 3664957

End: 3665913

Strand: Reverse

Name: trxB [H]

Synonym: Ppro_3328

Alternate gene names: 118581728

Gene position: 3665913-3664957 (Counterclockwise)

Preceding gene: 118581729

Following gene: 118581727

Centisome position: 91.46

GC content: 59.87

Gene sequence:

>957_bases
ATGGATTCGACCCATCACCCGCTACTCATTCTGGGCGCAGGCCCTGCCGGCTATACTGCCGCTATCTATGCAGCCCGGGC
AAACATTGTGCCCACGCTTATCACCGGTCTGCAACCCGGAGGCCAGCTCACCACCACCACCGAAGTCGACAATTGGCCGG
GAGATTATCAGGGAGTACAGGGCCCTGAACTGATGGAGCGGATGCGCCTGCATGCCGAGCGGTTCAACACCCGGATCATC
TACGACCACATCACACGTGCCGACCTGGGGCGGCGCCCCTTTCTGCTGGAGGGAGACTCGGCGGCCTACACCTGTGATGC
CCTGATCATAGCCACCGGCGCGTCGGCCAGATACCTGGGACTCCCTTCGGAACAGGCTTTTCTGGGCAAGGGGGTATCCG
GTTGCGCAACGTGTGACGGGTTCTTCTATCGCGGCAAGGATGTGGCGGTCATCGGTGGCGGCAGTACGGCGGTCGAAGAG
GCTCTCTATCTCTCCAATATCGCCCGGCACGTGACCATCGTGCATCGTCGCGACGAATTCAGGGCCGAAAAATACCTGGC
CAACCTGATCATCGAAAAATCAAAAAACGGCAACATCACCATAGAGTGGGATCATGTGCTGGATGAAGTGCTGGGTGATG
CAAGCGGCGTCACCGGCATGCGCATCCGCCACAAGAGCGGCCAGTCAACCAAGGAGATCCCGCTGCACGGCGTCTTCATC
GCCGTCGGCCACTCGCCCAACACGAAGATATTCGAGGGGCAGTTGGAAATGGACAACGGCTACATCCGCACGAAATGCGC
AAGCGTCGAGGGCAACATGACCGCAACCAGTGTCGAGGGTGTTTTTGCCGCGGGAGACGTTCAGGATTACATCTACCGCC
AGGCTGTGACGTCCGCCGCTTCCGGTTGCATGGCTGCTAAGGATGCCGAACACTACCTCGCCGCCCTGCGCCATTGA

Upstream 100 bases:

>100_bases
TACATCCAGGGTTCACGCCAGTTGTTCCCCCCCGGCAAACCCTCTTGGCAAGGCCGCGATTTGCTGGTACTGTTCCGCTA
TCATGCACGCAGGAGGAATC

Downstream 100 bases:

>100_bases
GTCATGTCCCTGCGAGTCACGGAAAACGACGATATCCAGAAACTGTTGGCCGAGGTTCGGCAAACGATCTGCGACAACCA
GCGTTTTCTCGGGAGATTGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MDSTHHPLLILGAGPAGYTAAIYAARANIVPTLITGLQPGGQLTTTTEVDNWPGDYQGVQGPELMERMRLHAERFNTRII
YDHITRADLGRRPFLLEGDSAAYTCDALIIATGASARYLGLPSEQAFLGKGVSGCATCDGFFYRGKDVAVIGGGSTAVEE
ALYLSNIARHVTIVHRRDEFRAEKYLANLIIEKSKNGNITIEWDHVLDEVLGDASGVTGMRIRHKSGQSTKEIPLHGVFI
AVGHSPNTKIFEGQLEMDNGYIRTKCASVEGNMTATSVEGVFAAGDVQDYIYRQAVTSAASGCMAAKDAEHYLAALRH

Sequences:

>Translated_318_residues
MDSTHHPLLILGAGPAGYTAAIYAARANIVPTLITGLQPGGQLTTTTEVDNWPGDYQGVQGPELMERMRLHAERFNTRII
YDHITRADLGRRPFLLEGDSAAYTCDALIIATGASARYLGLPSEQAFLGKGVSGCATCDGFFYRGKDVAVIGGGSTAVEE
ALYLSNIARHVTIVHRRDEFRAEKYLANLIIEKSKNGNITIEWDHVLDEVLGDASGVTGMRIRHKSGQSTKEIPLHGVFI
AVGHSPNTKIFEGQLEMDNGYIRTKCASVEGNMTATSVEGVFAAGDVQDYIYRQAVTSAASGCMAAKDAEHYLAALRH
>Mature_318_residues
MDSTHHPLLILGAGPAGYTAAIYAARANIVPTLITGLQPGGQLTTTTEVDNWPGDYQGVQGPELMERMRLHAERFNTRII
YDHITRADLGRRPFLLEGDSAAYTCDALIIATGASARYLGLPSEQAFLGKGVSGCATCDGFFYRGKDVAVIGGGSTAVEE
ALYLSNIARHVTIVHRRDEFRAEKYLANLIIEKSKNGNITIEWDHVLDEVLGDASGVTGMRIRHKSGQSTKEIPLHGVFI
AVGHSPNTKIFEGQLEMDNGYIRTKCASVEGNMTATSVEGVFAAGDVQDYIYRQAVTSAASGCMAAKDAEHYLAALRH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=64.1269841269841, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI87081763, Length=319, Percent_Identity=33.5423197492163, Blast_Score=138, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6321898, Length=323, Percent_Identity=45.8204334365325, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6320560, Length=327, Percent_Identity=45.2599388379205, Blast_Score=266, Evalue=3e-72,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34331; Mature: 34331

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTHHPLLILGAGPAGYTAAIYAARANIVPTLITGLQPGGQLTTTTEVDNWPGDYQGVQ
CCCCCCCEEEEECCCCCCHHEEEHHHCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCC
GPELMERMRLHAERFNTRIIYDHITRADLGRRPFLLEGDSAAYTCDALIIATGASARYLG
CHHHHHHHHHHHHHHCCEEEEECHHHHHCCCCCEEEECCCCEEEEEEEEEEECCCEEEEC
LPSEQAFLGKGVSGCATCDGFFYRGKDVAVIGGGSTAVEEALYLSNIARHVTIVHRRDEF
CCCCHHHHCCCCCCCEECCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEEECCHHH
RAEKYLANLIIEKSKNGNITIEWDHVLDEVLGDASGVTGMRIRHKSGQSTKEIPLHGVFI
HHHHHHHHHHEECCCCCCEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEE
AVGHSPNTKIFEGQLEMDNGYIRTKCASVEGNMTATSVEGVFAAGDVQDYIYRQAVTSAA
EECCCCCCEEEEEEEEECCCEEEEEEECCCCCEEEEEECCEEEECCHHHHHHHHHHHHHH
SGCMAAKDAEHYLAALRH
HCCHHHCCHHHHHHHHCC
>Mature Secondary Structure
MDSTHHPLLILGAGPAGYTAAIYAARANIVPTLITGLQPGGQLTTTTEVDNWPGDYQGVQ
CCCCCCCEEEEECCCCCCHHEEEHHHCCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCC
GPELMERMRLHAERFNTRIIYDHITRADLGRRPFLLEGDSAAYTCDALIIATGASARYLG
CHHHHHHHHHHHHHHCCEEEEECHHHHHCCCCCEEEECCCCEEEEEEEEEEECCCEEEEC
LPSEQAFLGKGVSGCATCDGFFYRGKDVAVIGGGSTAVEEALYLSNIARHVTIVHRRDEF
CCCCHHHHCCCCCCCEECCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEEECCHHH
RAEKYLANLIIEKSKNGNITIEWDHVLDEVLGDASGVTGMRIRHKSGQSTKEIPLHGVFI
HHHHHHHHHHEECCCCCCEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEE
AVGHSPNTKIFEGQLEMDNGYIRTKCASVEGNMTATSVEGVFAAGDVQDYIYRQAVTSAA
EECCCCCCEEEEEEEEECCCEEEEEEECCCCCEEEEEECCEEEECCHHHHHHHHHHHHHH
SGCMAAKDAEHYLAALRH
HCCHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]