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The map label for this gene is folE2 [H]

Identifier: 118581675

GI number: 118581675

Start: 3608779

End: 3609609

Strand: Reverse

Name: folE2 [H]

Synonym: Ppro_3275

Alternate gene names: 118581675

Gene position: 3609609-3608779 (Counterclockwise)

Preceding gene: 118581676

Following gene: 118581674

Centisome position: 90.06

GC content: 62.09

Gene sequence:

>831_bases
ATGAAGAAGAAAACAGCGACACCGGGCGCGACGCCCGGCAGCTCCCCGGCCCAGGCCATGCCAGACATGCAGAAGCGGCC
GGATCACCGCCGCATACCTATCTCCAAGGTGGGGGTCAAGGACATCAGCTACCCCATCGTGGTCATGGACAAAAATCGCT
CGCTCCAGCACACCGTGGCGCGGGTCAACATGTACGTGGACCTGCCGCACCAGTTCAAGGGAACCCACATGAGCCGCTTC
GTGGAGATCCTCAACCGCCACCGCGAGCAGATCGCCCTGGACAAGCTGGAGACGATCCTGGAGGAGATGAAGGCCAGGCT
CGGGTCGGCCAGCGCCCATCTGGAGATCCAGTTCCCCTACTTCATCGACAAGCGTGCCCCGGTTTCCGGCGCCAGGAGCC
TGATGGAGTATAGCTGCGAGTTCAGCGCCTCCCTGACCGACACCCTGGATTTCGTCCTGGGGGTCAGGGTACCGCTCACC
TCGCTCTGCCCCTGCAGCAGGGAACTGGCGATCCATGGCGCCCACAACCAGCGCAGCATCATGACCGTACGGGTGCGCTA
CCGGGATTTCATCTGGATCGAGGACCTGGTGGAGTTGATCGAGCAGTGCGGCAGCAGCCCGCTCTACTCCCTGCTGAAGA
GGGTGGACGAGAAGTACGTCACCGAGCAGGCCTACGAGAACCCCCGCTTTGTGGAGGACATGGTGCGTGAGGCTTACTCC
CGCCTGGCCGGTATGGAGAATATCACCTGGTTCTCGGTGGAGACGGAGAATTTCGAGTCGATCCACAACCATTCCGCCTA
TGCCGCCGTGGAACTGGACCGGAGAGGCTGA

Upstream 100 bases:

>100_bases
TTCTGCCCTTTCCCGCGACGGGCGCGATGCCGTCTGGAAAGAGGTCCTGCGGCTGACCCTGGCGCAGGAGGAAGAACGGA
TTTAACCGTCAGGAAGGCAT

Downstream 100 bases:

>100_bases
ACAGAGTTCAGCCCCGTTTCAGTACAGAGGGAAGCGCCAGCATGAGACCTGTCCTGATCATAACCGCCGTCCGCCAGGAA
GCGAAGCTTTTGGAAAAGGC

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MKKKTATPGATPGSSPAQAMPDMQKRPDHRRIPISKVGVKDISYPIVVMDKNRSLQHTVARVNMYVDLPHQFKGTHMSRF
VEILNRHREQIALDKLETILEEMKARLGSASAHLEIQFPYFIDKRAPVSGARSLMEYSCEFSASLTDTLDFVLGVRVPLT
SLCPCSRELAIHGAHNQRSIMTVRVRYRDFIWIEDLVELIEQCGSSPLYSLLKRVDEKYVTEQAYENPRFVEDMVREAYS
RLAGMENITWFSVETENFESIHNHSAYAAVELDRRG

Sequences:

>Translated_276_residues
MKKKTATPGATPGSSPAQAMPDMQKRPDHRRIPISKVGVKDISYPIVVMDKNRSLQHTVARVNMYVDLPHQFKGTHMSRF
VEILNRHREQIALDKLETILEEMKARLGSASAHLEIQFPYFIDKRAPVSGARSLMEYSCEFSASLTDTLDFVLGVRVPLT
SLCPCSRELAIHGAHNQRSIMTVRVRYRDFIWIEDLVELIEQCGSSPLYSLLKRVDEKYVTEQAYENPRFVEDMVREAYS
RLAGMENITWFSVETENFESIHNHSAYAAVELDRRG
>Mature_276_residues
MKKKTATPGATPGSSPAQAMPDMQKRPDHRRIPISKVGVKDISYPIVVMDKNRSLQHTVARVNMYVDLPHQFKGTHMSRF
VEILNRHREQIALDKLETILEEMKARLGSASAHLEIQFPYFIDKRAPVSGARSLMEYSCEFSASLTDTLDFVLGVRVPLT
SLCPCSRELAIHGAHNQRSIMTVRVRYRDFIWIEDLVELIEQCGSSPLYSLLKRVDEKYVTEQAYENPRFVEDMVREAYS
RLAGMENITWFSVETENFESIHNHSAYAAVELDRRG

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: =3.5.4.16 [H]

Molecular weight: Translated: 31606; Mature: 31606

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKTATPGATPGSSPAQAMPDMQKRPDHRRIPISKVGVKDISYPIVVMDKNRSLQHTVA
CCCCCCCCCCCCCCCHHHHCCCHHHCCCCCCCCHHHCCHHHCCCCEEEEECCCCHHHHHH
RVNMYVDLPHQFKGTHMSRFVEILNRHREQIALDKLETILEEMKARLGSASAHLEIQFPY
HHEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCE
FIDKRAPVSGARSLMEYSCEFSASLTDTLDFVLGVRVPLTSLCPCSRELAIHGAHNQRSI
EECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHEEECCCCCCEE
MTVRVRYRDFIWIEDLVELIEQCGSSPLYSLLKRVDEKYVTEQAYENPRFVEDMVREAYS
EEEEEHHHHEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RLAGMENITWFSVETENFESIHNHSAYAAVELDRRG
HHCCCCCCEEEEEECCCHHHHHCCCCEEEEEECCCC
>Mature Secondary Structure
MKKKTATPGATPGSSPAQAMPDMQKRPDHRRIPISKVGVKDISYPIVVMDKNRSLQHTVA
CCCCCCCCCCCCCCCHHHHCCCHHHCCCCCCCCHHHCCHHHCCCCEEEEECCCCHHHHHH
RVNMYVDLPHQFKGTHMSRFVEILNRHREQIALDKLETILEEMKARLGSASAHLEIQFPY
HHEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCE
FIDKRAPVSGARSLMEYSCEFSASLTDTLDFVLGVRVPLTSLCPCSRELAIHGAHNQRSI
EECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHEEECCCCCCEE
MTVRVRYRDFIWIEDLVELIEQCGSSPLYSLLKRVDEKYVTEQAYENPRFVEDMVREAYS
EEEEEHHHHEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RLAGMENITWFSVETENFESIHNHSAYAAVELDRRG
HHCCCCCCEEEEEECCCHHHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA