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The map label for this gene is mtnN [H]

Identifier: 118581674

GI number: 118581674

Start: 3607970

End: 3608737

Strand: Reverse

Name: mtnN [H]

Synonym: Ppro_3274

Alternate gene names: 118581674

Gene position: 3608737-3607970 (Counterclockwise)

Preceding gene: 118581675

Following gene: 118581672

Centisome position: 90.04

GC content: 64.71

Gene sequence:

>768_bases
ATGAGACCTGTCCTGATCATAACCGCCGTCCGCCAGGAAGCGAAGCTTTTGGAAAAGGCGCTGGTGGCGGCCTCGCGGGT
GAATACCCCCGCCTTTGCGACCGTGAACGGCATGCTGGGTGGCATAGCGGTGGTGATCTGCGTGGCCGGAGTCGGCAAGA
TTAATGCCGCGGCAGCCACCGCCGCCCTGATCGAGCGCCACAAGCCGCGACTGGTGATCAACACCGGCTGCGCCGGCGCC
TATCCGGGAAGTGGGCTTGCCATCGGCGACCTGGCGGTGGCAAGCGTGGAGATCCTGGGGGACGAAGGGGCGCTCACCTC
CCTGGGCTGGCTGGGACTGCGGGAGATGAAGCTTCCCTACCTGGTGCAGGGCACCCGGCGCTACTACAACGAGATCCCGC
TCTCCTGCCATATCTCCGAAAAAGCCGTGCAGTTGGCCGACTACTGCGGTATCGGCCTGGCCAGGGGGCGCTTCGTGACC
GTCTCCACCTGCAGCGGAACAACCCTCAAGGGGGAGGAACTGGTGCACCGCTTCGGCGCCCTGGCCGAGAACATGGAGGG
GGGAGCTGTTGCCCTGGTCTGCCTGCGTTACGGCGTAGACTGCCTTGAGATCAGGGGGATCAGCAACCTTGTGGAGGAGC
GCAACCTGGAGAACTGGGACATATCCCGGGCAGTTGAGGCTGCCCAGCGTTTCGTGCTGAAATACCTGGAGGAGATGGAC
CGCCCCGACTCTCACCCGCCGCGGCACTCGGTCGTCCCCGACGTATGA

Upstream 100 bases:

>100_bases
TCGAGTCGATCCACAACCATTCCGCCTATGCCGCCGTGGAACTGGACCGGAGAGGCTGAACAGAGTTCAGCCCCGTTTCA
GTACAGAGGGAAGCGCCAGC

Downstream 100 bases:

>100_bases
GCTGAATCCCCGGAAACAGATGCTTTCACGCCTGAAACCTGAACTTGCTACTCCTGCCCCCCTCTTTCGTCCACCGCCTT
ATTCCCCGCTGTCCTGCTTC

Product: purine phosphorylases family protein 1

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MRPVLIITAVRQEAKLLEKALVAASRVNTPAFATVNGMLGGIAVVICVAGVGKINAAAATAALIERHKPRLVINTGCAGA
YPGSGLAIGDLAVASVEILGDEGALTSLGWLGLREMKLPYLVQGTRRYYNEIPLSCHISEKAVQLADYCGIGLARGRFVT
VSTCSGTTLKGEELVHRFGALAENMEGGAVALVCLRYGVDCLEIRGISNLVEERNLENWDISRAVEAAQRFVLKYLEEMD
RPDSHPPRHSVVPDV

Sequences:

>Translated_255_residues
MRPVLIITAVRQEAKLLEKALVAASRVNTPAFATVNGMLGGIAVVICVAGVGKINAAAATAALIERHKPRLVINTGCAGA
YPGSGLAIGDLAVASVEILGDEGALTSLGWLGLREMKLPYLVQGTRRYYNEIPLSCHISEKAVQLADYCGIGLARGRFVT
VSTCSGTTLKGEELVHRFGALAENMEGGAVALVCLRYGVDCLEIRGISNLVEERNLENWDISRAVEAAQRFVLKYLEEMD
RPDSHPPRHSVVPDV
>Mature_255_residues
MRPVLIITAVRQEAKLLEKALVAASRVNTPAFATVNGMLGGIAVVICVAGVGKINAAAATAALIERHKPRLVINTGCAGA
YPGSGLAIGDLAVASVEILGDEGALTSLGWLGLREMKLPYLVQGTRRYYNEIPLSCHISEKAVQLADYCGIGLARGRFVT
VSTCSGTTLKGEELVHRFGALAENMEGGAVALVCLRYGVDCLEIRGISNLVEERNLENWDISRAVEAAQRFVLKYLEEMD
RPDSHPPRHSVVPDV

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 27250; Mature: 27250

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPVLIITAVRQEAKLLEKALVAASRVNTPAFATVNGMLGGIAVVICVAGVGKINAAAAT
CCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AALIERHKPRLVINTGCAGAYPGSGLAIGDLAVASVEILGDEGALTSLGWLGLREMKLPY
HHHHHHCCCCEEEECCCCCCCCCCCCEEHHHHHEEEEEECCCCCHHHHHHHCHHHCCCCH
LVQGTRRYYNEIPLSCHISEKAVQLADYCGIGLARGRFVTVSTCSGTTLKGEELVHRFGA
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
LAENMEGGAVALVCLRYGVDCLEIRGISNLVEERNLENWDISRAVEAAQRFVLKYLEEMD
HHHCCCCCHHHHHHHHHCCCCEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
RPDSHPPRHSVVPDV
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPVLIITAVRQEAKLLEKALVAASRVNTPAFATVNGMLGGIAVVICVAGVGKINAAAAT
CCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AALIERHKPRLVINTGCAGAYPGSGLAIGDLAVASVEILGDEGALTSLGWLGLREMKLPY
HHHHHHCCCCEEEECCCCCCCCCCCCEEHHHHHEEEEEECCCCCHHHHHHHCHHHCCCCH
LVQGTRRYYNEIPLSCHISEKAVQLADYCGIGLARGRFVTVSTCSGTTLKGEELVHRFGA
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
LAENMEGGAVALVCLRYGVDCLEIRGISNLVEERNLENWDISRAVEAAQRFVLKYLEEMD
HHHCCCCCHHHHHHHHHCCCCEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
RPDSHPPRHSVVPDV
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA