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The map label for this gene is hisE

Identifier: 118581457

GI number: 118581457

Start: 3341431

End: 3341757

Strand: Reverse

Name: hisE

Synonym: Ppro_3054

Alternate gene names: 118581457

Gene position: 3341757-3341431 (Counterclockwise)

Preceding gene: 118581458

Following gene: 118581456

Centisome position: 83.38

GC content: 51.68

Gene sequence:

>327_bases
ATGACAGAGCAGAATCACATTCTCGATGCCGTATACGGGGTTATTCTGGCGCGAAAGGCCACTCAGACGGAAAACTCTTA
CACCGCCAGCCTGATGAGGAAGGGGCTTGACTCTGTTCTGAAGAAAGTCGGTGAAGAAGCTACTGAACTGGTCATTGCCG
GTAAGGGAGGAGTGGCGGACGAGGTCGTATACGAGGCCGCCGACCTTTTTTTTCATACCCTGCTGCTGCTTAGCTATCAG
GACATTCCGCTGGAAAGAGTGTATACCGAACTGCGTCGCCGTTTCGGTATCTCCGGTATAGACGAGAAGAATTCCAGAAC
AACGTGA

Upstream 100 bases:

>100_bases
GCGCCAGTGCCTGTCTGGCCGCCTCCATTTTTCATTACCGCGAATATTCCATCGGAGAGGCCAAACAGTATCTTAAGGAG
AGAGGGGTGCCGGTCCGCCT

Downstream 100 bases:

>100_bases
CCCGGGGCAGCTGCTCTGGAATTTGTTGTTGACAAAAATTGAATATCTGTTAGTGTTAAAAACTTGCTATTTTGTATGGG
CTGTGTGTGAAGCACAACAG

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MTEQNHILDAVYGVILARKATQTENSYTASLMRKGLDSVLKKVGEEATELVIAGKGGVADEVVYEAADLFFHTLLLLSYQ
DIPLERVYTELRRRFGISGIDEKNSRTT

Sequences:

>Translated_108_residues
MTEQNHILDAVYGVILARKATQTENSYTASLMRKGLDSVLKKVGEEATELVIAGKGGVADEVVYEAADLFFHTLLLLSYQ
DIPLERVYTELRRRFGISGIDEKNSRTT
>Mature_107_residues
TEQNHILDAVYGVILARKATQTENSYTASLMRKGLDSVLKKVGEEATELVIAGKGGVADEVVYEAADLFFHTLLLLSYQD
IPLERVYTELRRRFGISGIDEKNSRTT

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS2_PELPD (A1ATH9)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902707.1
- ProteinModelPortal:   A1ATH9
- SMR:   A1ATH9
- STRING:   A1ATH9
- GeneID:   4574099
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3054
- eggNOG:   COG0140
- HOGENOM:   HBG646527
- OMA:   EMRRREN
- ProtClustDB:   PRK00400
- GO:   GO:0005737
- HAMAP:   MF_01020
- InterPro:   IPR008179
- InterPro:   IPR021130
- TIGRFAMs:   TIGR03188

Pfam domain/function: PF01503 PRA-PH

EC number: =3.6.1.31

Molecular weight: Translated: 12051; Mature: 11920

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQNHILDAVYGVILARKATQTENSYTASLMRKGLDSVLKKVGEEATELVIAGKGGVAD
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
EVVYEAADLFFHTLLLLSYQDIPLERVYTELRRRFGISGIDEKNSRTT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TEQNHILDAVYGVILARKATQTENSYTASLMRKGLDSVLKKVGEEATELVIAGKGGVAD
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHH
EVVYEAADLFFHTLLLLSYQDIPLERVYTELRRRFGISGIDEKNSRTT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA