Click here to switch to the map view.

The map label for this gene is yicO [C]

Identifier: 118581408

GI number: 118581408

Start: 3276155

End: 3277456

Strand: Reverse

Name: yicO [C]

Synonym: Ppro_3003

Alternate gene names: 118581408

Gene position: 3277456-3276155 (Counterclockwise)

Preceding gene: 118581409

Following gene: 118581404

Centisome position: 81.77

GC content: 64.59

Gene sequence:

>1302_bases
GTGAAACGGTTCTTCCGCTTCGAGCGCTACAATACCAGCTTTCGTCAGGAAACTCTGGCCGGGGTGACCACCTTCCTGAC
CATGGCCTACATTATCATCGTCAACCCGGCCATCATGGAGAACGCCGGCATCCCCCGGGGAGCGTCGATCACCGCCACCA
TCCTGGCAGCTGTCATCGGTACGGTGATCATGGCGCTCTGGGCGCGGCGCCCCTTTGCCATCGCCCCCTACATGGGGGAG
AACGCCTTCATCGCCTTCGTGGTGGTCAAGGTGATGGGCTACAGCTGGCAGGCTGCCCTAGGGGGGGTGTTCATCGCCGG
CGCGCTCTTCACCTTGCTGACCCTGTTCGGCATCCGCGGCTGGCTGGCCGAGTCCATCCCCCTGTCCCTCAAGGCCGGCT
TTGCCGTGGGGATCGGCCTGTTTCTGACCTTCATCGGCCTGAACGAGACCGGCCTGGTGGTGTTGGGGGTTCCGGGAGCG
CCGGTCAGGCTGGGTAATCTGGGGGAGCCCTCCTGCCTGCTGGCGGTGGCCGGTTTCCTGCTGGTGACGGCGCTCATGGC
CCTCCGGGTGCGCGGCGCCCTTTTGATCGGCATCATGGCCGCCACCCTGGGCTCCATAAGCCTGGGGCTTACCCCCCTGC
CGGACAGCATTGCCAGCCTTCCTCCGTCACTGGAGCCGATCCTGTTCAAGCTGGACATCGCCGGCGCGCTCTCGGTTTCG
TTCCTGCCGGTGGTGGCGGTGATCTTCATCATGGCCTTCCTGGATACGGTGGGCACCCTGATCGGACTCTCCATGCGTGC
CGACCTGCTGGACGAGAACGGCAACCTGCCGGAGATCGAGCGCCCCATGTTGGCCGACTCCCTGGCCACCATGGCCGCCC
CGCTCCTGGGTACCTCCACTACCGGCGCCTACATCGAGTCGGCCGCCGGTATCGAGGAGGGGGGGCGCACCGGTTTCTCG
GCCCTGGTTGTGGCGCTCCTCTTCCTGCTGTCGCTGTTCTTCGCCCCGCTCTTCACCATCGTCCCTCCCCACGCCTATGG
CATCGCCCTGGTAGTGATCGGTTCCTTCATGATCCGCCCCATCACCCGCATCGATTTCGACGATGTGACCGAGTTGGTGC
CTGCCTTCCTGACCATCTGCCTGATGGCGTTCACCTACAATATCGGGGTGGGGATGACCGCGGGGATGATCACCCATGTC
CTGCTCAAGCTGTTCACCGGCAGGGGGGGCGAGGTCAAGCCGGGCATGTGGGTGCTGGCGCTTCTGTCGATGCTCTTGTT
CGTCTGCCTGCCCAAGCTCTGA

Upstream 100 bases:

>100_bases
CTGGAAATCGGCGATCGTTTCCTGTTCGGATACGGCCTGGACTACAAGGGGTACTGGCGCAACGCGCCCGGAATTTTTGC
GGTGAAAGGGATGTGAGGCA

Downstream 100 bases:

>100_bases
ACGGATCGGTCCGTACCGCTTTACAGCCCGCTCCTGAGAGAAGAGGGGTGAGGGGAGTCGGCCGGGCCATTGGCGGGAAA
CAGGACGCGGAAGACACTCC

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MKRFFRFERYNTSFRQETLAGVTTFLTMAYIIIVNPAIMENAGIPRGASITATILAAVIGTVIMALWARRPFAIAPYMGE
NAFIAFVVVKVMGYSWQAALGGVFIAGALFTLLTLFGIRGWLAESIPLSLKAGFAVGIGLFLTFIGLNETGLVVLGVPGA
PVRLGNLGEPSCLLAVAGFLLVTALMALRVRGALLIGIMAATLGSISLGLTPLPDSIASLPPSLEPILFKLDIAGALSVS
FLPVVAVIFIMAFLDTVGTLIGLSMRADLLDENGNLPEIERPMLADSLATMAAPLLGTSTTGAYIESAAGIEEGGRTGFS
ALVVALLFLLSLFFAPLFTIVPPHAYGIALVVIGSFMIRPITRIDFDDVTELVPAFLTICLMAFTYNIGVGMTAGMITHV
LLKLFTGRGGEVKPGMWVLALLSMLLFVCLPKL

Sequences:

>Translated_433_residues
MKRFFRFERYNTSFRQETLAGVTTFLTMAYIIIVNPAIMENAGIPRGASITATILAAVIGTVIMALWARRPFAIAPYMGE
NAFIAFVVVKVMGYSWQAALGGVFIAGALFTLLTLFGIRGWLAESIPLSLKAGFAVGIGLFLTFIGLNETGLVVLGVPGA
PVRLGNLGEPSCLLAVAGFLLVTALMALRVRGALLIGIMAATLGSISLGLTPLPDSIASLPPSLEPILFKLDIAGALSVS
FLPVVAVIFIMAFLDTVGTLIGLSMRADLLDENGNLPEIERPMLADSLATMAAPLLGTSTTGAYIESAAGIEEGGRTGFS
ALVVALLFLLSLFFAPLFTIVPPHAYGIALVVIGSFMIRPITRIDFDDVTELVPAFLTICLMAFTYNIGVGMTAGMITHV
LLKLFTGRGGEVKPGMWVLALLSMLLFVCLPKL
>Mature_433_residues
MKRFFRFERYNTSFRQETLAGVTTFLTMAYIIIVNPAIMENAGIPRGASITATILAAVIGTVIMALWARRPFAIAPYMGE
NAFIAFVVVKVMGYSWQAALGGVFIAGALFTLLTLFGIRGWLAESIPLSLKAGFAVGIGLFLTFIGLNETGLVVLGVPGA
PVRLGNLGEPSCLLAVAGFLLVTALMALRVRGALLIGIMAATLGSISLGLTPLPDSIASLPPSLEPILFKLDIAGALSVS
FLPVVAVIFIMAFLDTVGTLIGLSMRADLLDENGNLPEIERPMLADSLATMAAPLLGTSTTGAYIESAAGIEEGGRTGFS
ALVVALLFLLSLFFAPLFTIVPPHAYGIALVVIGSFMIRPITRIDFDDVTELVPAFLTICLMAFTYNIGVGMTAGMITHV
LLKLFTGRGGEVKPGMWVLALLSMLLFVCLPKL

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=422, Percent_Identity=38.6255924170616, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1790150, Length=428, Percent_Identity=39.018691588785, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1790499, Length=430, Percent_Identity=34.6511627906977, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI48994909, Length=413, Percent_Identity=33.8983050847458, Blast_Score=216, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45784; Mature: 45784

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFFRFERYNTSFRQETLAGVTTFLTMAYIIIVNPAIMENAGIPRGASITATILAAVIG
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHH
TVIMALWARRPFAIAPYMGENAFIAFVVVKVMGYSWQAALGGVFIAGALFTLLTLFGIRG
HHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAESIPLSLKAGFAVGIGLFLTFIGLNETGLVVLGVPGAPVRLGNLGEPSCLLAVAGFL
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHH
LVTALMALRVRGALLIGIMAATLGSISLGLTPLPDSIASLPPSLEPILFKLDIAGALSVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEEEHHHHHHHH
FLPVVAVIFIMAFLDTVGTLIGLSMRADLLDENGNLPEIERPMLADSLATMAAPLLGTST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
TGAYIESAAGIEEGGRTGFSALVVALLFLLSLFFAPLFTIVPPHAYGIALVVIGSFMIRP
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ITRIDFDDVTELVPAFLTICLMAFTYNIGVGMTAGMITHVLLKLFTGRGGEVKPGMWVLA
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LLSMLLFVCLPKL
HHHHHHHHHCCCC
>Mature Secondary Structure
MKRFFRFERYNTSFRQETLAGVTTFLTMAYIIIVNPAIMENAGIPRGASITATILAAVIG
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHH
TVIMALWARRPFAIAPYMGENAFIAFVVVKVMGYSWQAALGGVFIAGALFTLLTLFGIRG
HHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAESIPLSLKAGFAVGIGLFLTFIGLNETGLVVLGVPGAPVRLGNLGEPSCLLAVAGFL
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHH
LVTALMALRVRGALLIGIMAATLGSISLGLTPLPDSIASLPPSLEPILFKLDIAGALSVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEEEHHHHHHHH
FLPVVAVIFIMAFLDTVGTLIGLSMRADLLDENGNLPEIERPMLADSLATMAAPLLGTST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
TGAYIESAAGIEEGGRTGFSALVVALLFLLSLFFAPLFTIVPPHAYGIALVVIGSFMIRP
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ITRIDFDDVTELVPAFLTICLMAFTYNIGVGMTAGMITHVLLKLFTGRGGEVKPGMWVLA
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LLSMLLFVCLPKL
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]