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The map label for this gene is hfq [H]

Identifier: 118581369

GI number: 118581369

Start: 3235452

End: 3235676

Strand: Direct

Name: hfq [H]

Synonym: Ppro_2964

Alternate gene names: 118581369

Gene position: 3235452-3235676 (Clockwise)

Preceding gene: 118581368

Following gene: 118581370

Centisome position: 80.72

GC content: 52.44

Gene sequence:

>225_bases
ATGGCAAAGGCCCCGTTCAACATTCAGGATCAGTACCTCAACCAGTCCCGGAAGGAACGCGTCAAGGTGATCGTCACCAT
GATGTCCGGTGACAAGCTGGAAGGGTATATCAAATCATTCGACAACTTCTCCGTACTGTTGGACTTGAACTGCGATGTCC
TGGTCTACAAGCACGCCATCTCCACCATCACCTCTGCCGACGGTTCATTCCGGCTGCACCAGTAA

Upstream 100 bases:

>100_bases
ATGCCGACCCGGAGATTATATGGCTTGAATATCCGGAAAAGTTTGCTACTATTTTGCGACATTGCATTGCATTTTTCGAA
TGACAGGAGGGATGACACCC

Downstream 100 bases:

>100_bases
TCATGTCCCGGCCCGCGGAGCCCCAGGCTTCGCGGCAAGCCTCCCCCTTTTGGCACTTCATGCACGCAAGCACAAAAATC
CTGTTGGCCCTCTCCCTGAC

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 74; Mature: 73

Protein sequence:

>74_residues
MAKAPFNIQDQYLNQSRKERVKVIVTMMSGDKLEGYIKSFDNFSVLLDLNCDVLVYKHAISTITSADGSFRLHQ

Sequences:

>Translated_74_residues
MAKAPFNIQDQYLNQSRKERVKVIVTMMSGDKLEGYIKSFDNFSVLLDLNCDVLVYKHAISTITSADGSFRLHQ
>Mature_73_residues
AKAPFNIQDQYLNQSRKERVKVIVTMMSGDKLEGYIKSFDNFSVLLDLNCDVLVYKHAISTITSADGSFRLHQ

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=63, Percent_Identity=49.2063492063492, Blast_Score=62, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 8441; Mature: 8310

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAPFNIQDQYLNQSRKERVKVIVTMMSGDKLEGYIKSFDNFSVLLDLNCDVLVYKHAI
CCCCCCCCCHHHCCHHHHCEEEEEEEECCCCCHHHHHHCCCCEEEEEECCCCEEEEHHHH
STITSADGSFRLHQ
HHHHCCCCCEEECC
>Mature Secondary Structure 
AKAPFNIQDQYLNQSRKERVKVIVTMMSGDKLEGYIKSFDNFSVLLDLNCDVLVYKHAI
CCCCCCCCHHHCCHHHHCEEEEEEEECCCCCHHHHHHCCCCEEEEEECCCCEEEEHHHH
STITSADGSFRLHQ
HHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA