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The map label for this gene is rnhA

Identifier: 118581344

GI number: 118581344

Start: 3213003

End: 3213494

Strand: Direct

Name: rnhA

Synonym: Ppro_2939

Alternate gene names: 118581344

Gene position: 3213003-3213494 (Clockwise)

Preceding gene: 118581343

Following gene: 118581347

Centisome position: 80.16

GC content: 63.62

Gene sequence:

>492_bases
ATGTCGGCCAGGCCTGATCAGTCACGAACCGCCGCCCCATCAGCAACGACCTCCCCGGTGGAAATCTACTGCGACGGCGC
CTGCAGCGGCAATCCCGGGCCGGGCGGCTACGGCGCCATCCTGCGCTATAACGGCCATGAGAAGGAAATTCGCGGCAGCG
AGGCACATACCACCAACAACCGCATGGAACTGACCGCCGCCATGGAGGCGCTGCGTCTTTTGACCCGTCCCTGCCGGATC
ACCATCGTCACCGACTCGCAGTATCTGGTAAAGGGGATGACCGAGTGGATCCAGGGATGGCAGCGCAGAGGGTGGCAGAA
CAGCAAGAAGGAGCCGGTGCTCAACCGCGACCTGTGGGAGGAACTGCTCAAGCTCAGTGCCCATCACGATGTCAGCTGGC
AATGGATTCGCGGCCATGCCGGCCATGCCGAAAACGAGCGCTGCGACAGCCTGGCGCGCCAGGCGATAACAGAGATGAGG
GGCGCCCCCTGA

Upstream 100 bases:

>100_bases
AGCGACCTGTACGCCATGCCCAACAGCAAGGAGACCCACCAGTTGATCGTGGAGCGGGTCATGGACGCCATTGCGGAACA
ACTGAAACAGGAGGGCGCCT

Downstream 100 bases:

>100_bases
GGAAGTTCCCGTCGCGCCCGGCAGGAACGGGCGGAGCCAGATAAAAAAAAAGACGCTGTCCAGGGACGCGTCATTCGTGC
CGAAAGGCATCAAACCAGCA

Product: ribonuclease H

Products: NA

Alternate protein names: RNase H

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MSARPDQSRTAAPSATTSPVEIYCDGACSGNPGPGGYGAILRYNGHEKEIRGSEAHTTNNRMELTAAMEALRLLTRPCRI
TIVTDSQYLVKGMTEWIQGWQRRGWQNSKKEPVLNRDLWEELLKLSAHHDVSWQWIRGHAGHAENERCDSLARQAITEMR
GAP

Sequences:

>Translated_163_residues
MSARPDQSRTAAPSATTSPVEIYCDGACSGNPGPGGYGAILRYNGHEKEIRGSEAHTTNNRMELTAAMEALRLLTRPCRI
TIVTDSQYLVKGMTEWIQGWQRRGWQNSKKEPVLNRDLWEELLKLSAHHDVSWQWIRGHAGHAENERCDSLARQAITEMR
GAP
>Mature_162_residues
SARPDQSRTAAPSATTSPVEIYCDGACSGNPGPGGYGAILRYNGHEKEIRGSEAHTTNNRMELTAAMEALRLLTRPCRIT
IVTDSQYLVKGMTEWIQGWQRRGWQNSKKEPVLNRDLWEELLKLSAHHDVSWQWIRGHAGHAENERCDSLARQAITEMRG
AP

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain

Homologues:

Organism=Homo sapiens, GI21359816, Length=140, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI1786408, Length=136, Percent_Identity=55.8823529411765, Blast_Score=172, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI115532542, Length=147, Percent_Identity=36.734693877551, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17137476, Length=142, Percent_Identity=35.2112676056338, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI45552509, Length=142, Percent_Identity=35.2112676056338, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH_PELPD (A1AT66)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902594.1
- ProteinModelPortal:   A1AT66
- STRING:   A1AT66
- GeneID:   4574561
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2939
- eggNOG:   COG0328
- HOGENOM:   HBG742437
- OMA:   NGWRTAD
- PhylomeDB:   A1AT66
- GO:   GO:0005737
- HAMAP:   MF_00042
- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156

Pfam domain/function: PF00075 RnaseH; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 18270; Mature: 18139

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARPDQSRTAAPSATTSPVEIYCDGACSGNPGPGGYGAILRYNGHEKEIRGSEAHTTNN
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCC
RMELTAAMEALRLLTRPCRITIVTDSQYLVKGMTEWIQGWQRRGWQNSKKEPVLNRDLWE
HHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
ELLKLSAHHDVSWQWIRGHAGHAENERCDSLARQAITEMRGAP
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SARPDQSRTAAPSATTSPVEIYCDGACSGNPGPGGYGAILRYNGHEKEIRGSEAHTTNN
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCC
RMELTAAMEALRLLTRPCRITIVTDSQYLVKGMTEWIQGWQRRGWQNSKKEPVLNRDLWE
HHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
ELLKLSAHHDVSWQWIRGHAGHAENERCDSLARQAITEMRGAP
HHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA