Click here to switch to the map view.

The map label for this gene is fkpB [C]

Identifier: 118581316

GI number: 118581316

Start: 3186014

End: 3186481

Strand: Direct

Name: fkpB [C]

Synonym: Ppro_2911

Alternate gene names: 118581316

Gene position: 3186014-3186481 (Clockwise)

Preceding gene: 118581313

Following gene: 118581317

Centisome position: 79.49

GC content: 55.56

Gene sequence:

>468_bases
ATGGCACACGCTAAGAATGGCGACAAGGTAAAATTTCATTACAGCGCCACCCTGGAAGACGGCACTGTTTTCGACTCCAC
CTACGAAGAAATCTGCGAAGAAGAAGAATGCGGCTGCGAGGGCGAGATCGGCCCGATGGAACTGACCATCGGCGCGGGTG
AGTTCTTCCCGGAGATTGAGCAGGCGCTGATCGGCATGGCCGTAGGCGAGAAGAAAAAGGTGATGATCCCCTCGGCGGAT
GCCTTTGGCGAATACGACCAGGAGAAGATCTTCACCGCCAAGCGGGACGAAATTCCCGAAGACCTGCAGCCGGAAGTGGG
CGATGCCTATACGCTGGCCAACGACAACGACGAAGAGGTGGATGTAACCGTCGTGGAGGTAACCGCTGACAGCGTCACCT
TCGACTCCAATCACCCCCTGGCAGGCGAAGACCTGAACTTTGAAATCGAACTGATAGAGATCTTCTAG

Upstream 100 bases:

>100_bases
GCGTGGTAACGATTTTTGTAGACTGCCGGCCGCTGTTTCCCGTATTCTGACGGGCACAAATAATCGGCGCAAAGCCTACC
ACACACTGAAAGGTACAACA

Downstream 100 bases:

>100_bases
AGAGTTCCCCCCACGGATTCACTGCACAACGACTTCCGGGGCCGTGCCCGGGAGTCGTTGTTTTTTTGCGTCCGCACCAT
CGCCCCCATGACCCCATCCC

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MAHAKNGDKVKFHYSATLEDGTVFDSTYEEICEEEECGCEGEIGPMELTIGAGEFFPEIEQALIGMAVGEKKKVMIPSAD
AFGEYDQEKIFTAKRDEIPEDLQPEVGDAYTLANDNDEEVDVTVVEVTADSVTFDSNHPLAGEDLNFEIELIEIF

Sequences:

>Translated_155_residues
MAHAKNGDKVKFHYSATLEDGTVFDSTYEEICEEEECGCEGEIGPMELTIGAGEFFPEIEQALIGMAVGEKKKVMIPSAD
AFGEYDQEKIFTAKRDEIPEDLQPEVGDAYTLANDNDEEVDVTVVEVTADSVTFDSNHPLAGEDLNFEIELIEIF
>Mature_154_residues
AHAKNGDKVKFHYSATLEDGTVFDSTYEEICEEEECGCEGEIGPMELTIGAGEFFPEIEQALIGMAVGEKKKVMIPSADA
FGEYDQEKIFTAKRDEIPEDLQPEVGDAYTLANDNDEEVDVTVVEVTADSVTFDSNHPLAGEDLNFEIELIEIF

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786211, Length=150, Percent_Identity=29.3333333333333, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17123; Mature: 16992

Theoretical pI: Translated: 3.68; Mature: 3.68

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHAKNGDKVKFHYSATLEDGTVFDSTYEEICEEEECGCEGEIGPMELTIGAGEFFPEIE
CCCCCCCCEEEEEEEEECCCCEEECHHHHHHCCHHHCCCCCCCCCEEEEEECCHHHHHHH
QALIGMAVGEKKKVMIPSADAFGEYDQEKIFTAKRDEIPEDLQPEVGDAYTLANDNDEEV
HHHHHHHCCCCCEEEECCCHHCCCCCCHHEEECCCCCCCCCCCCCCCCEEEECCCCCCEE
DVTVVEVTADSVTFDSNHPLAGEDLNFEIELIEIF
EEEEEEEEECEEEECCCCCCCCCCCCEEEEEEEEC
>Mature Secondary Structure 
AHAKNGDKVKFHYSATLEDGTVFDSTYEEICEEEECGCEGEIGPMELTIGAGEFFPEIE
CCCCCCCEEEEEEEEECCCCEEECHHHHHHCCHHHCCCCCCCCCEEEEEECCHHHHHHH
QALIGMAVGEKKKVMIPSADAFGEYDQEKIFTAKRDEIPEDLQPEVGDAYTLANDNDEEV
HHHHHHHCCCCCEEEECCCHHCCCCCCHHEEECCCCCCCCCCCCCCCCEEEECCCCCCEE
DVTVVEVTADSVTFDSNHPLAGEDLNFEIELIEIF
EEEEEEEEECEEEECCCCCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]