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The map label for this gene is groES

Identifier: 118581210

GI number: 118581210

Start: 3069338

End: 3069625

Strand: Reverse

Name: groES

Synonym: Ppro_2803

Alternate gene names: 118581210

Gene position: 3069625-3069338 (Counterclockwise)

Preceding gene: 118581219

Following gene: 118581209

Centisome position: 76.59

GC content: 56.25

Gene sequence:

>288_bases
ATGAAATTGAGACCGCTTCATGACCGCATCCTCGTCAAGAGGGTCGAAGAAGAAACCAAGACCGCAGGGGGCCTCTTCAT
CCCCGAAACCGCCAAGGAAAAGCCGCAGCGCGGCGAAGTTGTTGCCGCCGGTAATGGCAAGAAGACCGAGGACGGCAAGG
TACTGCCGCTGGATGTCAAGGTTGGCGACAAGGTGCTGTTCGGCAAGTACTCCGGCACCGAAGTGAAGGTGGATGGTGAA
GATTTCCTGATGATGCGCGAGGACGACATTCTCGCTGTCGTTGAGTAA

Upstream 100 bases:

>100_bases
AGTGCTGATTATATTCCTGAAAGTTAGCACTCGGTCATCGTGAGTGCTAATTCTGTCTTCGATACGAAAACCACCACAGC
ATAAGAAAGGAGAAGTACCG

Downstream 100 bases:

>100_bases
CCCCTATCTCTTTTATTGCGGGGGCGCGTGACATGCTCCGAGCAAATGCGGCATAGTGAGGGCGAATCGTTATCGCCTCT
CCCCCAACAGGCACTTTATT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MKLRPLHDRILVKRVEEETKTAGGLFIPETAKEKPQRGEVVAAGNGKKTEDGKVLPLDVKVGDKVLFGKYSGTEVKVDGE
DFLMMREDDILAVVE

Sequences:

>Translated_95_residues
MKLRPLHDRILVKRVEEETKTAGGLFIPETAKEKPQRGEVVAAGNGKKTEDGKVLPLDVKVGDKVLFGKYSGTEVKVDGE
DFLMMREDDILAVVE
>Mature_95_residues
MKLRPLHDRILVKRVEEETKTAGGLFIPETAKEKPQRGEVVAAGNGKKTEDGKVLPLDVKVGDKVLFGKYSGTEVKVDGE
DFLMMREDDILAVVE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=46.6666666666667, Blast_Score=73, Evalue=5e-14,
Organism=Homo sapiens, GI169210012, Length=90, Percent_Identity=43.3333333333333, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=55.2083333333333, Blast_Score=103, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17555568, Length=91, Percent_Identity=45.0549450549451, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324594, Length=90, Percent_Identity=44.4444444444444, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358317, Length=96, Percent_Identity=44.7916666666667, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=42.2680412371134, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_PELPD (A1AST2)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902460.1
- ProteinModelPortal:   A1AST2
- SMR:   A1AST2
- STRING:   A1AST2
- GeneID:   4573670
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2803
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- PhylomeDB:   A1AST2
- ProtClustDB:   PRK00364
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10510; Mature: 10510

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRPLHDRILVKRVEEETKTAGGLFIPETAKEKPQRGEVVAAGNGKKTEDGKVLPLDVK
CCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
VGDKVLFGKYSGTEVKVDGEDFLMMREDDILAVVE
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MKLRPLHDRILVKRVEEETKTAGGLFIPETAKEKPQRGEVVAAGNGKKTEDGKVLPLDVK
CCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
VGDKVLFGKYSGTEVKVDGEDFLMMREDDILAVVE
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA