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The map label for this gene is hypA [H]

Identifier: 118581189

GI number: 118581189

Start: 3044165

End: 3044497

Strand: Reverse

Name: hypA [H]

Synonym: Ppro_2782

Alternate gene names: 118581189

Gene position: 3044497-3044165 (Counterclockwise)

Preceding gene: 118581190

Following gene: 118581188

Centisome position: 75.96

GC content: 54.65

Gene sequence:

>333_bases
ATGCATGAGTTGACCATTATGAAGAACGTGGTGTCGATCTGTGAGCAGAATGCTGCCGGGAGTCGGGTGACGTCCGTAAC
CCTGGACGTGGGTGAACTGTCCGGCATCGTCCCCGGCGCCCTCGAATTCTGCTTCGATTCATGCACCAAGGGTACCCTTC
TGGAGGGTGCCAGCCTGAAAATTATTATCATCGAACCCCAGGTTCGCTGCAACGGCTGCAAGGCTCTGTTCGGCGCCCGG
GCTTATCACGACTCATGCCCCGAATGTGGTGGTTTCGATATCGAGATTCTCTTTGGTGAGGAACTTCGGGTAAAAGAACT
GGAGGTAGTGTAG

Upstream 100 bases:

>100_bases
TTAGCTCAGGCGTAAAATGTGAGACTATCAGCCACTGAAACGTCGCAACCGGTCTATGCGGTGCGTAACGGAAGCAGTAC
CCTGACAGCGAGGATTGTTG

Downstream 100 bases:

>100_bases
CGTTATGTGTACGACATGCGGTTGCCCCACCGTGGGAGAACATTCCCACGACCATGACCATGGTCACGATCATAGCCATG
ACCATACCCATACCCATGAT

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MHELTIMKNVVSICEQNAAGSRVTSVTLDVGELSGIVPGALEFCFDSCTKGTLLEGASLKIIIIEPQVRCNGCKALFGAR
AYHDSCPECGGFDIEILFGEELRVKELEVV

Sequences:

>Translated_110_residues
MHELTIMKNVVSICEQNAAGSRVTSVTLDVGELSGIVPGALEFCFDSCTKGTLLEGASLKIIIIEPQVRCNGCKALFGAR
AYHDSCPECGGFDIEILFGEELRVKELEVV
>Mature_110_residues
MHELTIMKNVVSICEQNAAGSRVTSVTLDVGELSGIVPGALEFCFDSCTKGTLLEGASLKIIIIEPQVRCNGCKALFGAR
AYHDSCPECGGFDIEILFGEELRVKELEVV

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=32.1428571428571, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1789081, Length=115, Percent_Identity=31.304347826087, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 11836; Mature: 11836

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
6.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELTIMKNVVSICEQNAAGSRVTSVTLDVGELSGIVPGALEFCFDSCTKGTLLEGASLK
CCCHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHCCCCHHHHHHHHHCCCCCCEECCCCEE
IIIIEPQVRCNGCKALFGARAYHDSCPECGGFDIEILFGEELRVKELEVV
EEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECC
>Mature Secondary Structure
MHELTIMKNVVSICEQNAAGSRVTSVTLDVGELSGIVPGALEFCFDSCTKGTLLEGASLK
CCCHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHCCCCHHHHHHHHHCCCCCCEECCCCEE
IIIIEPQVRCNGCKALFGARAYHDSCPECGGFDIEILFGEELRVKELEVV
EEEECCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA