Click here to switch to the map view.

The map label for this gene is surE

Identifier: 118581145

GI number: 118581145

Start: 2996635

End: 2997378

Strand: Direct

Name: surE

Synonym: Ppro_2737

Alternate gene names: 118581145

Gene position: 2996635-2997378 (Clockwise)

Preceding gene: 118581143

Following gene: 118581146

Centisome position: 74.77

GC content: 63.84

Gene sequence:

>744_bases
ATGCATATTATGGTAACCAACGACGACGGCATCCAGGCCCCGGGCATCCAGGCACTTGCCTCGGCCCTGCGGGTTTTGGG
CGAGGTAACCGTCGTGGCGCCCGACCGGGAGCGGAGCGCCGTGGGACATGCCCTGACCCTGAACTCCCCCCTGCGGGTAT
TCGAGTTGCGTGACGGCTTCTACGCCGTGGACGGCACCCCAACCGACTGCGTCAACATGGGCATCCACAGCCTGCTCCCC
TTCCGACCCGACCTGATCGTCTCCGGGATCAACCACGGCGCCAACCTGGGCGACGACGTGACCTACTCCGGCACAGTGGC
GGCCGCCATCGAGGCGACCCTGATGGGCATCCCGGCCATCGCCGTCTCCCTGGCCACACAGGAGCGGAGCGGCCATTTTC
CCGAGGCTGCCCAGATTGCCGTCCGGGTGGCCCGCCAGGTCTTGTCAAACGGCCTCCCCGAGGACACCTTCCTGAACGTC
AACGTTCCCGACTGCCCCGCTGAAGAGATCAGGCCGCCGCTGGTCACCCGCCAGGGCAAGCGTTCCTTTGTGGGCAACGT
GATCGACAAAACCGACCCCCGCGGCCGCAAGTACTACTGGATAGGCAGCGGTGAGGCGGACTTCAACGATTACGAGGGGA
CCGACTTCCACGCCATCAACAGGAAACATGTCTCGATTACGCCACTGCACCTGGACCTGACCAACTACGCATCCATGAAG
GTGATCACCACCTGGGTTTTTTAG

Upstream 100 bases:

>100_bases
TGGCGGATAAACGGCAGCTAGGATGGTTCCTTGATTTTTGGATATTTTTCTGCCATAACTGGCTGGTTTTGAAGGCACAA
AAACCAACCGGATAGATCCT

Downstream 100 bases:

>100_bases
CGCCGCCGGCCCGTGCGGGCACCTGGAGCATTGCATGAATTTCGATAGAGCACGTAAAAAGATGGTTCAGGAACAGATCG
CGACCCGCGGAATCACCGAC

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MHIMVTNDDGIQAPGIQALASALRVLGEVTVVAPDRERSAVGHALTLNSPLRVFELRDGFYAVDGTPTDCVNMGIHSLLP
FRPDLIVSGINHGANLGDDVTYSGTVAAAIEATLMGIPAIAVSLATQERSGHFPEAAQIAVRVARQVLSNGLPEDTFLNV
NVPDCPAEEIRPPLVTRQGKRSFVGNVIDKTDPRGRKYYWIGSGEADFNDYEGTDFHAINRKHVSITPLHLDLTNYASMK
VITTWVF

Sequences:

>Translated_247_residues
MHIMVTNDDGIQAPGIQALASALRVLGEVTVVAPDRERSAVGHALTLNSPLRVFELRDGFYAVDGTPTDCVNMGIHSLLP
FRPDLIVSGINHGANLGDDVTYSGTVAAAIEATLMGIPAIAVSLATQERSGHFPEAAQIAVRVARQVLSNGLPEDTFLNV
NVPDCPAEEIRPPLVTRQGKRSFVGNVIDKTDPRGRKYYWIGSGEADFNDYEGTDFHAINRKHVSITPLHLDLTNYASMK
VITTWVF
>Mature_247_residues
MHIMVTNDDGIQAPGIQALASALRVLGEVTVVAPDRERSAVGHALTLNSPLRVFELRDGFYAVDGTPTDCVNMGIHSLLP
FRPDLIVSGINHGANLGDDVTYSGTVAAAIEATLMGIPAIAVSLATQERSGHFPEAAQIAVRVARQVLSNGLPEDTFLNV
NVPDCPAEEIRPPLVTRQGKRSFVGNVIDKTDPRGRKYYWIGSGEADFNDYEGTDFHAINRKHVSITPLHLDLTNYASMK
VITTWVF

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=247, Percent_Identity=48.582995951417, Blast_Score=229, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_PELPD (A1ASL7)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902395.1
- ProteinModelPortal:   A1ASL7
- SMR:   A1ASL7
- STRING:   A1ASL7
- GeneID:   4574567
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2737
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- PhylomeDB:   A1ASL7
- ProtClustDB:   PRK00346
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 26760; Mature: 26760

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIMVTNDDGIQAPGIQALASALRVLGEVTVVAPDRERSAVGHALTLNSPLRVFELRDGF
CEEEEECCCCCCCCCHHHHHHHHHHHHCEEEEECCCCHHHCCEEEEECCCEEEEEECCCE
YAVDGTPTDCVNMGIHSLLPFRPDLIVSGINHGANLGDDVTYSGTVAAAIEATLMGIPAI
EEECCCCHHHHHHCHHHHCCCCCCCEEECCCCCCCCCCCCEECCCHHHHHHHHHHCCCHH
AVSLATQERSGHFPEAAQIAVRVARQVLSNGLPEDTFLNVNVPDCPAEEIRPPLVTRQGK
EEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCCCCCCCCCC
RSFVGNVIDKTDPRGRKYYWIGSGEADFNDYEGTDFHAINRKHVSITPLHLDLTNYASMK
HHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCEE
VITTWVF
EEEEECC
>Mature Secondary Structure
MHIMVTNDDGIQAPGIQALASALRVLGEVTVVAPDRERSAVGHALTLNSPLRVFELRDGF
CEEEEECCCCCCCCCHHHHHHHHHHHHCEEEEECCCCHHHCCEEEEECCCEEEEEECCCE
YAVDGTPTDCVNMGIHSLLPFRPDLIVSGINHGANLGDDVTYSGTVAAAIEATLMGIPAI
EEECCCCHHHHHHCHHHHCCCCCCCEEECCCCCCCCCCCCEECCCHHHHHHHHHHCCCHH
AVSLATQERSGHFPEAAQIAVRVARQVLSNGLPEDTFLNVNVPDCPAEEIRPPLVTRQGK
EEEEEHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCCCCCCCCCC
RSFVGNVIDKTDPRGRKYYWIGSGEADFNDYEGTDFHAINRKHVSITPLHLDLTNYASMK
HHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCEE
VITTWVF
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA