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The map label for this gene is gmhB [H]

Identifier: 118580961

GI number: 118580961

Start: 2762780

End: 2763340

Strand: Reverse

Name: gmhB [H]

Synonym: Ppro_2549

Alternate gene names: 118580961

Gene position: 2763340-2762780 (Counterclockwise)

Preceding gene: 118580963

Following gene: 118580960

Centisome position: 68.95

GC content: 65.95

Gene sequence:

>561_bases
ATGCGGCGGGCGGTCTTTCTGGACAGGGACGGTACCATCAATCAGGAGCGGGAGTATCTCCACCGCGTCGAGGATTTTTG
CTTCATCGCCGACGTGCCCTGGGCCATCAGCCTGCTGAACCGGGCGGGATTCCTGGTGGTGGTGGTCACCAACCAGTCCG
GCGTGGCGCGCGGCTACTACGCTGAAAAGGATGTGGAGGCGCTGCATCGCCACATCGCGGCCCAGTTAACAGCCGCCGGG
GCACGGGTCGACTTCTGGCTGTACTGTCCCCATCATCCGGACGGCAGGGGGGCTTACGCCGTCTCCTGCTCCTGCCGCAA
GCCGCTTCCCGGTATGCTGCTGGAGGCGGCGGACAGGCTGGACATCGACCTGGCCTCGTCGTTCATGATCGGCGACAAGC
TGAGCGACGTAGAGGCCGGCCGCGCGGCCGGATGCAGTCCCATTCTGGTGCGCAGCGGATACGGCGCCGATGAGGAGTCC
CGCCTCCCCCCCGGCGTTGCCGTGTACGATGACCTGCTGGCCGCGGCGATATCCCTTGCCGCCATGTGCGATGGTGTTTG
A

Upstream 100 bases:

>100_bases
TTGTTGGTTTTGATCATGGTTCATGGTCCGTTTTCGTGGATTTGCCGGCTGACCGGCTATTGTTATCGGTTTCACGGTGG
TTTGTCAAAGGAGTTTTACT

Downstream 100 bases:

>100_bases
CAGGTTTTTTTCCGCAGTGTAAATTTCACACTCATTTTTTCCAGGAGGTTTATGTCATGTCCCGTGGAATCACCAAGGGA
ATCGTGCTGGCAGGTGGAGC

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MRRAVFLDRDGTINQEREYLHRVEDFCFIADVPWAISLLNRAGFLVVVVTNQSGVARGYYAEKDVEALHRHIAAQLTAAG
ARVDFWLYCPHHPDGRGAYAVSCSCRKPLPGMLLEAADRLDIDLASSFMIGDKLSDVEAGRAAGCSPILVRSGYGADEES
RLPPGVAVYDDLLAAAISLAAMCDGV

Sequences:

>Translated_186_residues
MRRAVFLDRDGTINQEREYLHRVEDFCFIADVPWAISLLNRAGFLVVVVTNQSGVARGYYAEKDVEALHRHIAAQLTAAG
ARVDFWLYCPHHPDGRGAYAVSCSCRKPLPGMLLEAADRLDIDLASSFMIGDKLSDVEAGRAAGCSPILVRSGYGADEES
RLPPGVAVYDDLLAAAISLAAMCDGV
>Mature_186_residues
MRRAVFLDRDGTINQEREYLHRVEDFCFIADVPWAISLLNRAGFLVVVVTNQSGVARGYYAEKDVEALHRHIAAQLTAAG
ARVDFWLYCPHHPDGRGAYAVSCSCRKPLPGMLLEAADRLDIDLASSFMIGDKLSDVEAGRAAGCSPILVRSGYGADEES
RLPPGVAVYDDLLAAAISLAAMCDGV

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=152, Percent_Identity=48.0263157894737, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI87082027, Length=148, Percent_Identity=29.7297297297297, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20157; Mature: 20157

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAVFLDRDGTINQEREYLHRVEDFCFIADVPWAISLLNRAGFLVVVVTNQSGVARGYY
CCCEEEECCCCCCCHHHHHHHHHHHEEEEECCHHHHHHHHCCCEEEEEEECCCCCCCCCC
AEKDVEALHRHIAAQLTAAGARVDFWLYCPHHPDGRGAYAVSCSCRKPLPGMLLEAADRL
CHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHC
DIDLASSFMIGDKLSDVEAGRAAGCSPILVRSGYGADEESRLPPGVAVYDDLLAAAISLA
CHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AMCDGV
HHHCCC
>Mature Secondary Structure
MRRAVFLDRDGTINQEREYLHRVEDFCFIADVPWAISLLNRAGFLVVVVTNQSGVARGYY
CCCEEEECCCCCCCHHHHHHHHHHHEEEEECCHHHHHHHHCCCEEEEEEECCCCCCCCCC
AEKDVEALHRHIAAQLTAAGARVDFWLYCPHHPDGRGAYAVSCSCRKPLPGMLLEAADRL
CHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHC
DIDLASSFMIGDKLSDVEAGRAAGCSPILVRSGYGADEESRLPPGVAVYDDLLAAAISLA
CHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AMCDGV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286; 12101286 [H]