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The map label for this gene is yggW [H]

Identifier: 118580893

GI number: 118580893

Start: 2685757

End: 2687118

Strand: Reverse

Name: yggW [H]

Synonym: Ppro_2480

Alternate gene names: 118580893

Gene position: 2687118-2685757 (Counterclockwise)

Preceding gene: 118580894

Following gene: 118580891

Centisome position: 67.04

GC content: 56.39

Gene sequence:

>1362_bases
ATGCAGCGAAATGCCGCTCTTGACAGGATACGGAACGAACTGTTCTACGGTTCGTGCAACTATACGAAAAGCCAGCCAGA
TCTGTTCGTTCCCCAGCATTTTACCATGTTGGCGCCTTCGAAGGCTTCCTCGTTCATTGACACGGTCGTTGCTGCCATGG
TTGAAACTGAACTTTTGCTGTACATCCATCTTCCCTTCTGCTTTTCAGAATGCTTGTTTTGTAATTCCTTTCCCCACAAA
GTTGATACCCAGGTCCAGCAGGAGTACCTCAGGCGCCTTATTCTGCAGATAGAGCTGTACGAGCGGCTTGGACTCTTTAA
GGGCAAAAAGGCCAAGTGCATCTGTTTCGGGGGAGGGACGCCCACCGCTTTCGCGAACAGCGAGATCAGGAAAGTCATGG
ATACGGTTCGCGCATGCGTTACCCTGACCGATGACTGCAGTATTGCCACGGAAGCCCATCCGGCAACCATGGAGCACGAA
GCCCGGGTCCTCGATCTGGCAGACATGGGGTTCAACCGCATCAGTATGGGCTGCCAGACCTTCGATCCGCAGATCCTTCA
GCTCTGCAACAGAAACAACACCCCCAGCCAGGTTCAGGGCATCGTGCAAACGGTGCAGCGGGCCGGCATGATGATCAACA
TCGATATGATGACCGGTCTCCCCGGTCAGTCGATTGAGAGCGTACAGGCGGATCTCCGCATGCTGGAGCAGATCCGCCCC
GACGCCGTCGAGTACATCCGGCACGAAATCGTCAATCCCCTGATCGCGCGGTTGTATACCCAGCGGCCCGAACTGATCGT
TCCCGATGACACGCTCTTTGACATGGTGTTCATGGCCCAGGAGTGGATGGATGGTCAGGGCTACGAACAGAATGGCCGCT
TCAGCTGCGACCGGCAGTGGCCCTACCGCTATCACTGGCTGCGGGAAACGCCGATCATCTCCTTCGGTATCAGAACCAGA
TCCTACTCGCCCGCGATCTGCTTTGACAGCCACGAAGAACTGGCCAGCTTCAATCGCCTGGTGGATAAGGGGATTCCGCC
CGTGGGACGGTATATCATGTTGTCCCGGCGGGAGCGCATGTACCGGAGACTGATCCTGAGCCTGCAGCTGAAGGGTGGTC
TCGACATCAGCCGCTTTCACGCCAGCTTTGGAGAGAGTCCCCTGGATGTGTTCAGCCCACTTGTCTCGAAACTCGCAGAT
CTGGGCTGTCTCTGCCAGGAGGATGAATCCCTGCGTCTGACCCGGCTGGGCGCCTATTTTGTAGAGGATGTGTGCGACTG
CATTATCGATAGCGCCTTGCAGGAAGAATCACGCGGTCTTGTACGGGCGCCCCATTCAGGCGGCAGCATGTTCCGTCGTT
GA

Upstream 100 bases:

>100_bases
CAGACAGGTTGTGTAAGAATATAAGTACTGACTTACACTACAGTCAGGTGCAACGGGTGATGGCAGGATTGCCTTGTCAC
CGGTTCTACGGGAACTATGT

Downstream 100 bases:

>100_bases
TTCCTGGCTGCGTACGGCCCCCTCCACTTTTTGCCCTCGAAACACCCTTCATTCCCCCCCCCTCGTTACGCGGCGCCCCT
TCACTTTCTCTTACCCTTGC

Product: radical SAM domain-containing protein

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MQRNAALDRIRNELFYGSCNYTKSQPDLFVPQHFTMLAPSKASSFIDTVVAAMVETELLLYIHLPFCFSECLFCNSFPHK
VDTQVQQEYLRRLILQIELYERLGLFKGKKAKCICFGGGTPTAFANSEIRKVMDTVRACVTLTDDCSIATEAHPATMEHE
ARVLDLADMGFNRISMGCQTFDPQILQLCNRNNTPSQVQGIVQTVQRAGMMINIDMMTGLPGQSIESVQADLRMLEQIRP
DAVEYIRHEIVNPLIARLYTQRPELIVPDDTLFDMVFMAQEWMDGQGYEQNGRFSCDRQWPYRYHWLRETPIISFGIRTR
SYSPAICFDSHEELASFNRLVDKGIPPVGRYIMLSRRERMYRRLILSLQLKGGLDISRFHASFGESPLDVFSPLVSKLAD
LGCLCQEDESLRLTRLGAYFVEDVCDCIIDSALQEESRGLVRAPHSGGSMFRR

Sequences:

>Translated_453_residues
MQRNAALDRIRNELFYGSCNYTKSQPDLFVPQHFTMLAPSKASSFIDTVVAAMVETELLLYIHLPFCFSECLFCNSFPHK
VDTQVQQEYLRRLILQIELYERLGLFKGKKAKCICFGGGTPTAFANSEIRKVMDTVRACVTLTDDCSIATEAHPATMEHE
ARVLDLADMGFNRISMGCQTFDPQILQLCNRNNTPSQVQGIVQTVQRAGMMINIDMMTGLPGQSIESVQADLRMLEQIRP
DAVEYIRHEIVNPLIARLYTQRPELIVPDDTLFDMVFMAQEWMDGQGYEQNGRFSCDRQWPYRYHWLRETPIISFGIRTR
SYSPAICFDSHEELASFNRLVDKGIPPVGRYIMLSRRERMYRRLILSLQLKGGLDISRFHASFGESPLDVFSPLVSKLAD
LGCLCQEDESLRLTRLGAYFVEDVCDCIIDSALQEESRGLVRAPHSGGSMFRR
>Mature_453_residues
MQRNAALDRIRNELFYGSCNYTKSQPDLFVPQHFTMLAPSKASSFIDTVVAAMVETELLLYIHLPFCFSECLFCNSFPHK
VDTQVQQEYLRRLILQIELYERLGLFKGKKAKCICFGGGTPTAFANSEIRKVMDTVRACVTLTDDCSIATEAHPATMEHE
ARVLDLADMGFNRISMGCQTFDPQILQLCNRNNTPSQVQGIVQTVQRAGMMINIDMMTGLPGQSIESVQADLRMLEQIRP
DAVEYIRHEIVNPLIARLYTQRPELIVPDDTLFDMVFMAQEWMDGQGYEQNGRFSCDRQWPYRYHWLRETPIISFGIRTR
SYSPAICFDSHEELASFNRLVDKGIPPVGRYIMLSRRERMYRRLILSLQLKGGLDISRFHASFGESPLDVFSPLVSKLAD
LGCLCQEDESLRLTRLGAYFVEDVCDCIIDSALQEESRGLVRAPHSGGSMFRR

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=177, Percent_Identity=25.9887005649718, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1789325, Length=235, Percent_Identity=30.2127659574468, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI87082341, Length=411, Percent_Identity=25.7907542579075, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 51702; Mature: 51702

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRNAALDRIRNELFYGSCNYTKSQPDLFVPQHFTMLAPSKASSFIDTVVAAMVETELLL
CCCHHHHHHHHHHHEECCCCCCCCCCCEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHE
YIHLPFCFSECLFCNSFPHKVDTQVQQEYLRRLILQIELYERLGLFKGKKAKCICFGGGT
EEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
PTAFANSEIRKVMDTVRACVTLTDDCSIATEAHPATMEHEARVLDLADMGFNRISMGCQT
CCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHCCHHEEEHHHCCCHHHHCCCCC
FDPQILQLCNRNNTPSQVQGIVQTVQRAGMMINIDMMTGLPGQSIESVQADLRMLEQIRP
CCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCH
DAVEYIRHEIVNPLIARLYTQRPELIVPDDTLFDMVFMAQEWMDGQGYEQNGRFSCDRQW
HHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCC
PYRYHWLRETPIISFGIRTRSYSPAICFDSHEELASFNRLVDKGIPPVGRYIMLSRRERM
CCCEEEEECCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
YRRLILSLQLKGGLDISRFHASFGESPLDVFSPLVSKLADLGCLCQEDESLRLTRLGAYF
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VEDVCDCIIDSALQEESRGLVRAPHSGGSMFRR
HHHHHHHHHHHHHHHHCCCCEECCCCCCHHCCC
>Mature Secondary Structure
MQRNAALDRIRNELFYGSCNYTKSQPDLFVPQHFTMLAPSKASSFIDTVVAAMVETELLL
CCCHHHHHHHHHHHEECCCCCCCCCCCEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHE
YIHLPFCFSECLFCNSFPHKVDTQVQQEYLRRLILQIELYERLGLFKGKKAKCICFGGGT
EEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
PTAFANSEIRKVMDTVRACVTLTDDCSIATEAHPATMEHEARVLDLADMGFNRISMGCQT
CCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCHHCCHHEEEHHHCCCHHHHCCCCC
FDPQILQLCNRNNTPSQVQGIVQTVQRAGMMINIDMMTGLPGQSIESVQADLRMLEQIRP
CCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCH
DAVEYIRHEIVNPLIARLYTQRPELIVPDDTLFDMVFMAQEWMDGQGYEQNGRFSCDRQW
HHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCC
PYRYHWLRETPIISFGIRTRSYSPAICFDSHEELASFNRLVDKGIPPVGRYIMLSRRERM
CCCEEEEECCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
YRRLILSLQLKGGLDISRFHASFGESPLDVFSPLVSKLADLGCLCQEDESLRLTRLGAYF
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VEDVCDCIIDSALQEESRGLVRAPHSGGSMFRR
HHHHHHHHHHHHHHHHCCCCEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]