Click here to switch to the map view.

The map label for this gene is aspS [H]

Identifier: 118580744

GI number: 118580744

Start: 2514358

End: 2516142

Strand: Reverse

Name: aspS [H]

Synonym: Ppro_2329

Alternate gene names: 118580744

Gene position: 2516142-2514358 (Counterclockwise)

Preceding gene: 118580745

Following gene: 118580743

Centisome position: 62.78

GC content: 63.42

Gene sequence:

>1785_bases
ATGGAGACTCTGGGTAGCTGGAAACGCACACAGTACTGCGGCGAACTGACCGGCCGGCATATCGGCCAGGAGGTGATTCT
GATGGGGTGGGCCCTGCGCCGCCGCGACCATGGCGGGCTGATCTTCATCGACCTGCGCGACCGCGAGGGGATCGCCCAGG
TCGTCTTCGACCCCGAGGTCAATGGTCAGGCCCACGCCATTGCCGAGACCGTGCGCAGCGAGTTTGTCCTGGCAATCAAG
GGAGAGGTGATTCCCCGCCCCGCGGGAACGGTCAACCCCAACATGAAGACCGGCGAGGTGGAGATCAGGGTCAGCGAATG
CAAGCTGCTCAGCCGCTCCAAGGCGCTCCCCTTCATGCTGGACGAGTTCAGCGAGGTCAACGAGAACATCCGCCTCAAGC
ACCGCTACCTTGACCTGCGCCGGCCGCAGCTGCAGCAGAATCTGATCCTGCGCTCAAAGGTTTCCCAGCTCACCCGCAGC
TACCTGACCGACAACGGCTTTCTGGAGATGGAGACCCCCTTCCTGACCAAGTCCACCCCCGAGGGGGCCCGGGACTTCCT
GGTGCCGTCGCGCATCAACCAGGGCTCTTTCTACGCGCTGCCCCAGTCTCCCCAGATCTTCAAGCAGATCCTAATGATCT
CCGGCTTCGACCGCTACTTCCAGGTGGTGCGCTGCTTCCGTGACGAGGACCTGCGCGCCGACCGCCAGCCGGAGTTCACC
CAGATCGACTGCGAGATGTCCTTCATCGACCGCGAGGACATCATCGCCGTGATGGAGGGGCTGATCGCCACCGTGTTCAA
GCAGGCCAAGGGGGTGGATGTGCAGCTCCCCATCCAGCACATCACCTATGACGAGGCCATCCGCCGCTTCGGTGTGGACA
ACCCCGATCTCCGCTTCGGCATGGAGCTGTGCCAGTTGACCGACATCGTCAAGGGGTCCGGTTTCAAGGTCTTCGCCGAT
ACCGCCGCCAAGGGGGGGATCGTCAAGGGGATCAACGCCAAGGGGTGCGCCCGCTTCTCCCGCAAGGAGATCGACGACCT
GACCGAATTCGTCAGGATCTACGGCGCCAAGGGGCTGGCCTATGTCAAGATCGAGAACAATGAGTGGCGTTCCCCCATCG
CCAAGTTCTTCACTCCGGAGGAGATCGGCGCCATGAACGAGGCTTTCGGCGCCGAGGAGGGGGACCTGCTCTTCTTCGTG
GCCGACAAGCCCAAGGTGGTCAACGATTCCCTGGGCAAGCTGCGCAACCACTTGGCCTCCCTGCTCAAACTGACCAGCAA
TGACGACTACCGCTTTGTCTGGGTGACCGAGTTCCCCCTCCTGGAGTGGGACGACGAGGATAAGCGCTGGGCAGCAGTGC
ACCATCCCTTCACCGCCCCCATGGACGAGGACCTGCCGCTCCTGGAGAGCGACCCGGGGCGCTGCCGCGCCAAGGCCTAC
GATCTGGTGCTGAACGGCAACGAGATCGGCGGCGGCTCCATCAGGATCCACCAGGAGCAGGTCCAGTCGCGCATGTTCGA
GCTTCTGGGCATGTCCGACGAATCCGCGCGCTCCAAGTTCGGCTTCCTGCTGGATGCCCTGGAGTTCGGCACCCCCCCCC
ATGGCGGCATCGCCTTTGGCCTGGACCGCCTGATCATGCTGATGACCGGCAGCGAATCCATCCGCGACGTGATCGCCTTC
CCCAAGACCCAGAAGGGAGCCTGCCTGATGTCCGAGGCGCCTTCGCGGGTGGAGACCAAGCAGTTGCGCGAACTGGGGAT
CAGGCTGGCGGAAAAGCAGGTCTAG

Upstream 100 bases:

>100_bases
TCCGCCTTGGTATGCGCCGCGAGTTCAACCTGAAAACGCGCTTCAGGTTCCCGCGTTTTGGGTTCAGATACACTTATAAT
TACATTGAATGGAGAAGATA

Downstream 100 bases:

>100_bases
GCCGCAATTCCATGAGCCGCCGGCCCCTCGCCATAGCGCTCCTGGTCGGCTCCCTGCTGGTCTCCTGCGCTGCACCGGCG
CCCACCTGGCGCACCCAGGC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
METLGSWKRTQYCGELTGRHIGQEVILMGWALRRRDHGGLIFIDLRDREGIAQVVFDPEVNGQAHAIAETVRSEFVLAIK
GEVIPRPAGTVNPNMKTGEVEIRVSECKLLSRSKALPFMLDEFSEVNENIRLKHRYLDLRRPQLQQNLILRSKVSQLTRS
YLTDNGFLEMETPFLTKSTPEGARDFLVPSRINQGSFYALPQSPQIFKQILMISGFDRYFQVVRCFRDEDLRADRQPEFT
QIDCEMSFIDREDIIAVMEGLIATVFKQAKGVDVQLPIQHITYDEAIRRFGVDNPDLRFGMELCQLTDIVKGSGFKVFAD
TAAKGGIVKGINAKGCARFSRKEIDDLTEFVRIYGAKGLAYVKIENNEWRSPIAKFFTPEEIGAMNEAFGAEEGDLLFFV
ADKPKVVNDSLGKLRNHLASLLKLTSNDDYRFVWVTEFPLLEWDDEDKRWAAVHHPFTAPMDEDLPLLESDPGRCRAKAY
DLVLNGNEIGGGSIRIHQEQVQSRMFELLGMSDESARSKFGFLLDALEFGTPPHGGIAFGLDRLIMLMTGSESIRDVIAF
PKTQKGACLMSEAPSRVETKQLRELGIRLAEKQV

Sequences:

>Translated_594_residues
METLGSWKRTQYCGELTGRHIGQEVILMGWALRRRDHGGLIFIDLRDREGIAQVVFDPEVNGQAHAIAETVRSEFVLAIK
GEVIPRPAGTVNPNMKTGEVEIRVSECKLLSRSKALPFMLDEFSEVNENIRLKHRYLDLRRPQLQQNLILRSKVSQLTRS
YLTDNGFLEMETPFLTKSTPEGARDFLVPSRINQGSFYALPQSPQIFKQILMISGFDRYFQVVRCFRDEDLRADRQPEFT
QIDCEMSFIDREDIIAVMEGLIATVFKQAKGVDVQLPIQHITYDEAIRRFGVDNPDLRFGMELCQLTDIVKGSGFKVFAD
TAAKGGIVKGINAKGCARFSRKEIDDLTEFVRIYGAKGLAYVKIENNEWRSPIAKFFTPEEIGAMNEAFGAEEGDLLFFV
ADKPKVVNDSLGKLRNHLASLLKLTSNDDYRFVWVTEFPLLEWDDEDKRWAAVHHPFTAPMDEDLPLLESDPGRCRAKAY
DLVLNGNEIGGGSIRIHQEQVQSRMFELLGMSDESARSKFGFLLDALEFGTPPHGGIAFGLDRLIMLMTGSESIRDVIAF
PKTQKGACLMSEAPSRVETKQLRELGIRLAEKQV
>Mature_594_residues
METLGSWKRTQYCGELTGRHIGQEVILMGWALRRRDHGGLIFIDLRDREGIAQVVFDPEVNGQAHAIAETVRSEFVLAIK
GEVIPRPAGTVNPNMKTGEVEIRVSECKLLSRSKALPFMLDEFSEVNENIRLKHRYLDLRRPQLQQNLILRSKVSQLTRS
YLTDNGFLEMETPFLTKSTPEGARDFLVPSRINQGSFYALPQSPQIFKQILMISGFDRYFQVVRCFRDEDLRADRQPEFT
QIDCEMSFIDREDIIAVMEGLIATVFKQAKGVDVQLPIQHITYDEAIRRFGVDNPDLRFGMELCQLTDIVKGSGFKVFAD
TAAKGGIVKGINAKGCARFSRKEIDDLTEFVRIYGAKGLAYVKIENNEWRSPIAKFFTPEEIGAMNEAFGAEEGDLLFFV
ADKPKVVNDSLGKLRNHLASLLKLTSNDDYRFVWVTEFPLLEWDDEDKRWAAVHHPFTAPMDEDLPLLESDPGRCRAKAY
DLVLNGNEIGGGSIRIHQEQVQSRMFELLGMSDESARSKFGFLLDALEFGTPPHGGIAFGLDRLIMLMTGSESIRDVIAF
PKTQKGACLMSEAPSRVETKQLRELGIRLAEKQV

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=594, Percent_Identity=43.6026936026936, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI194272210, Length=247, Percent_Identity=29.5546558704453, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI5031815, Length=247, Percent_Identity=29.5546558704453, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI45439306, Length=305, Percent_Identity=27.8688524590164, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4758762, Length=254, Percent_Identity=25.9842519685039, Blast_Score=74, Evalue=5e-13,
Organism=Escherichia coli, GI1788173, Length=591, Percent_Identity=50.5922165820643, Blast_Score=596, Evalue=1e-171,
Organism=Escherichia coli, GI1790571, Length=282, Percent_Identity=29.0780141843972, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789256, Length=283, Percent_Identity=28.6219081272085, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI32566633, Length=618, Percent_Identity=34.4660194174757, Blast_Score=331, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI71994340, Length=179, Percent_Identity=29.608938547486, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535927, Length=179, Percent_Identity=29.608938547486, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17535925, Length=152, Percent_Identity=30.2631578947368, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325153, Length=647, Percent_Identity=32.1483771251932, Blast_Score=297, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6323011, Length=284, Percent_Identity=25.3521126760563, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321807, Length=248, Percent_Identity=24.1935483870968, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320242, Length=177, Percent_Identity=28.2485875706215, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584738, Length=597, Percent_Identity=40.536013400335, Blast_Score=397, Evalue=1e-110,
Organism=Drosophila melanogaster, GI17136276, Length=274, Percent_Identity=26.2773722627737, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24640851, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640849, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67185; Mature: 67185

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLGSWKRTQYCGELTGRHIGQEVILMGWALRRRDHGGLIFIDLRDREGIAQVVFDPEV
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCC
NGQAHAIAETVRSEFVLAIKGEVIPRPAGTVNPNMKTGEVEIRVSECKLLSRSKALPFML
CCHHHHHHHHHHHCEEEEEECCEECCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCHHH
DEFSEVNENIRLKHRYLDLRRPQLQQNLILRSKVSQLTRSYLTDNGFLEMETPFLTKSTP
HHHHHCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
EGARDFLVPSRINQGSFYALPQSPQIFKQILMISGFDRYFQVVRCFRDEDLRADRQPEFT
CCHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCE
QIDCEMSFIDREDIIAVMEGLIATVFKQAKGVDVQLPIQHITYDEAIRRFGVDNPDLRFG
EEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECHHHCCHHHHHHHHCCCCCCHHHH
MELCQLTDIVKGSGFKVFADTAAKGGIVKGINAKGCARFSRKEIDDLTEFVRIYGAKGLA
HHHHHHHHHHCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
YVKIENNEWRSPIAKFFTPEEIGAMNEAFGAEEGDLLFFVADKPKVVNDSLGKLRNHLAS
EEEECCCCHHHHHHHHCCHHHHCCHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
LLKLTSNDDYRFVWVTEFPLLEWDDEDKRWAAVHHPFTAPMDEDLPLLESDPGRCRAKAY
HHHHCCCCCEEEEEEEECCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEE
DLVLNGNEIGGGSIRIHQEQVQSRMFELLGMSDESARSKFGFLLDALEFGTPPHGGIAFG
EEEEECCEECCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHH
LDRLIMLMTGSESIRDVIAFPKTQKGACLMSEAPSRVETKQLRELGIRLAEKQV
HHHHHEEECCCHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
METLGSWKRTQYCGELTGRHIGQEVILMGWALRRRDHGGLIFIDLRDREGIAQVVFDPEV
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCC
NGQAHAIAETVRSEFVLAIKGEVIPRPAGTVNPNMKTGEVEIRVSECKLLSRSKALPFML
CCHHHHHHHHHHHCEEEEEECCEECCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCHHH
DEFSEVNENIRLKHRYLDLRRPQLQQNLILRSKVSQLTRSYLTDNGFLEMETPFLTKSTP
HHHHHCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
EGARDFLVPSRINQGSFYALPQSPQIFKQILMISGFDRYFQVVRCFRDEDLRADRQPEFT
CCHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCE
QIDCEMSFIDREDIIAVMEGLIATVFKQAKGVDVQLPIQHITYDEAIRRFGVDNPDLRFG
EEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECHHHCCHHHHHHHHCCCCCCHHHH
MELCQLTDIVKGSGFKVFADTAAKGGIVKGINAKGCARFSRKEIDDLTEFVRIYGAKGLA
HHHHHHHHHHCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
YVKIENNEWRSPIAKFFTPEEIGAMNEAFGAEEGDLLFFVADKPKVVNDSLGKLRNHLAS
EEEECCCCHHHHHHHHCCHHHHCCHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
LLKLTSNDDYRFVWVTEFPLLEWDDEDKRWAAVHHPFTAPMDEDLPLLESDPGRCRAKAY
HHHHCCCCCEEEEEEEECCEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEE
DLVLNGNEIGGGSIRIHQEQVQSRMFELLGMSDESARSKFGFLLDALEFGTPPHGGIAFG
EEEEECCEECCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHH
LDRLIMLMTGSESIRDVIAFPKTQKGACLMSEAPSRVETKQLRELGIRLAEKQV
HHHHHEEECCCHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA