Click here to switch to the map view.

The map label for this gene is ruvB

Identifier: 118580736

GI number: 118580736

Start: 2507265

End: 2508281

Strand: Reverse

Name: ruvB

Synonym: Ppro_2321

Alternate gene names: 118580736

Gene position: 2508281-2507265 (Counterclockwise)

Preceding gene: 118580738

Following gene: 118580735

Centisome position: 62.58

GC content: 65.0

Gene sequence:

>1017_bases
ATGAGCCGCGCCATAGCCGCTGACAAGCGTGAAGATGATTCCCAGTTCGACAGCACCCTGAGACCCAAATCCCTGGACGA
TTACATCGGCCAGGAGAAGATAAAGGGTAACCTGCGCCTGTTCATCGAGGCTGCCCGGGGGAGGGGAGAGGCGCTGGACC
ATGTGCTGCTCTACGGCCCCCCCGGCCTGGGAAAGACGACCCTGGCCAACATAGTTGCCTGCGAGATGGGTGTCAACCTC
AAGTCCACATCCGGGCCGGTCATCGAGCGTCCCGGCGACCTGGCCGCCATCCTGACCAACCTGGAACCGCACGACGTCCT
GTTCATCGACGAGATTCACCGCCTCTCCCATGTGGTGGAGGAGATCCTCTACCCGGCCATGGAGGACTTCCAGCTGGATA
TCATCATCGGCCAGGGCCCCAGCGCGCGCTCCATCAAGCTGGACCTGCCCCGCTTTACCCTGGTGGGGGCAACCACCAGG
GCCGGCCTGCTTTCCTCGCCGCTGCGCGACCGCTTCGGCGTCATCTCGCGCATGGACTTCTACACCCATGACGAGCTGGC
CACCATCATCACCCGCTCCTCCCGCATCCTGGGCATGGAGATCGAACCCAGGGGGGCCGACGAACTCTCCCGCCGCAGCC
GCGGTACGCCGCGCATCGCCAACCGCCTGTTGCGCCGGGTGCGCGATTTTGCCCAGGTACGCGCCGACGGTGTCATCACC
CGTCAGGTGGTCAAGGAAACCCTGGCCCTGCTGGAGATAGACGAGATGGGCTTCGACCACATGGACCGCATGATCCTCCT
GACCATCATCGACAAGTTCTCCGGCGGCCCGGTGGGGCTGGACACCATCGCCGCCGCCATCAGCGAGGAGAGCGACACCA
TCGAGGACGTGTACGAGCCGTACATGATCCAGAACGGGTTCCTCAACCGCACCCCCCGCGGACGGGTGGCCACCCTTGCC
GCCTACGAGCACTTTGGCCGCTCCGTTCCCGCCGCCCCCCAGGCGGCCCTGTTGTGA

Upstream 100 bases:

>100_bases
TTGATTTTCCGTGCCTTGAGCGGGTATACTGCCCGACTGACAGTCGTCCCGCTATCGTCATGGCAGCGGGGCGGTTCCCG
AAAACGCCACCGGAGAAGCG

Downstream 100 bases:

>100_bases
CCATGCAGCAGATCCTCGAATTTCCGGTGTCATCCTCCTGCACCTTCGACAGCTTCGTCGTCTGCGACGGCAATGCCGCG
GCGGTGCGCTTTGCCCGGCG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSRAIAADKREDDSQFDSTLRPKSLDDYIGQEKIKGNLRLFIEAARGRGEALDHVLLYGPPGLGKTTLANIVACEMGVNL
KSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARSIKLDLPRFTLVGATTR
AGLLSSPLRDRFGVISRMDFYTHDELATIITRSSRILGMEIEPRGADELSRRSRGTPRIANRLLRRVRDFAQVRADGVIT
RQVVKETLALLEIDEMGFDHMDRMILLTIIDKFSGGPVGLDTIAAAISEESDTIEDVYEPYMIQNGFLNRTPRGRVATLA
AYEHFGRSVPAAPQAALL

Sequences:

>Translated_338_residues
MSRAIAADKREDDSQFDSTLRPKSLDDYIGQEKIKGNLRLFIEAARGRGEALDHVLLYGPPGLGKTTLANIVACEMGVNL
KSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARSIKLDLPRFTLVGATTR
AGLLSSPLRDRFGVISRMDFYTHDELATIITRSSRILGMEIEPRGADELSRRSRGTPRIANRLLRRVRDFAQVRADGVIT
RQVVKETLALLEIDEMGFDHMDRMILLTIIDKFSGGPVGLDTIAAAISEESDTIEDVYEPYMIQNGFLNRTPRGRVATLA
AYEHFGRSVPAAPQAALL
>Mature_337_residues
SRAIAADKREDDSQFDSTLRPKSLDDYIGQEKIKGNLRLFIEAARGRGEALDHVLLYGPPGLGKTTLANIVACEMGVNLK
STSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARSIKLDLPRFTLVGATTRA
GLLSSPLRDRFGVISRMDFYTHDELATIITRSSRILGMEIEPRGADELSRRSRGTPRIANRLLRRVRDFAQVRADGVITR
QVVKETLALLEIDEMGFDHMDRMILLTIIDKFSGGPVGLDTIAAAISEESDTIEDVYEPYMIQNGFLNRTPRGRVATLAA
YEHFGRSVPAAPQAALL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=331, Percent_Identity=63.7462235649547, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_PELPD (A1ARF8)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901986.1
- ProteinModelPortal:   A1ARF8
- SMR:   A1ARF8
- STRING:   A1ARF8
- GeneID:   4571638
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2321
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   A1ARF8
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37403; Mature: 37272

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAIAADKREDDSQFDSTLRPKSLDDYIGQEKIKGNLRLFIEAARGRGEALDHVLLYGP
CCCCCCCCCCCCHHHHHHCCCCCCHHHHHCHHHHCCCEEEEEEECCCCCCCCCEEEEECC
PGLGKTTLANIVACEMGVNLKSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVE
CCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDFQLDIIIGQGPSARSIKLDLPRFTLVGATTRAGLLSSPLRDRFGVISRMDF
HHHHHCCCCCEEEEEEECCCCCCEEEEECCCEEEEECCHHHHHHHCHHHHHHHHHHHHCC
YTHDELATIITRSSRILGMEIEPRGADELSRRSRGTPRIANRLLRRVRDFAQVRADGVIT
CCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHH
RQVVKETLALLEIDEMGFDHMDRMILLTIIDKFSGGPVGLDTIAAAISEESDTIEDVYEP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHCC
YMIQNGFLNRTPRGRVATLAAYEHFGRSVPAAPQAALL
HHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SRAIAADKREDDSQFDSTLRPKSLDDYIGQEKIKGNLRLFIEAARGRGEALDHVLLYGP
CCCCCCCCCCCHHHHHHCCCCCCHHHHHCHHHHCCCEEEEEEECCCCCCCCCEEEEECC
PGLGKTTLANIVACEMGVNLKSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVE
CCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDFQLDIIIGQGPSARSIKLDLPRFTLVGATTRAGLLSSPLRDRFGVISRMDF
HHHHHCCCCCEEEEEEECCCCCCEEEEECCCEEEEECCHHHHHHHCHHHHHHHHHHHHCC
YTHDELATIITRSSRILGMEIEPRGADELSRRSRGTPRIANRLLRRVRDFAQVRADGVIT
CCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHH
RQVVKETLALLEIDEMGFDHMDRMILLTIIDKFSGGPVGLDTIAAAISEESDTIEDVYEP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHCC
YMIQNGFLNRTPRGRVATLAAYEHFGRSVPAAPQAALL
HHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA