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The map label for this gene is dnaA [H]

Identifier: 118580735

GI number: 118580735

Start: 2506552

End: 2507262

Strand: Reverse

Name: dnaA [H]

Synonym: Ppro_2320

Alternate gene names: 118580735

Gene position: 2507262-2506552 (Counterclockwise)

Preceding gene: 118580736

Following gene: 118580734

Centisome position: 62.56

GC content: 66.24

Gene sequence:

>711_bases
ATGCAGCAGATCCTCGAATTTCCGGTGTCATCCTCCTGCACCTTCGACAGCTTCGTCGTCTGCGACGGCAATGCCGCGGC
GGTGCGCTTTGCCCGGCGCATAACCGACGAATCCGAGCCCGAGCGGCTGCTCTACCTGCACGGCCCCCCCGGTTCGGGCA
AGACACACCTGCTCCGGGCCATCGCCCTGGAACTGGCCGGCGGCAACCCCGACCAGGCACCCTACCTCTCCTGCCGGGAC
GTGCGTTCGGCGCGCTCCCTGGTGGACCGCTTCCATGGCGCGCAAGGGCTGGTGGTGGATGACCTGCAGTTGCTGCCCGA
TAGCCAGGACCTGCGGGCAGCGCTGTGGCAGCTGTTCAACGATTTTCACGAGGCCGGCCGTGCGGTGGTCCTGGCCGGGC
TGCACCCGCCGCGCATGCTGCCGCATCTGGACGATCACCTGGTGTCGCGCCTCTTGTGGGGACTGGTGGCCCGGGTTGAC
GCCTCCGACGACCTTTCTCGGCGCATGATCCTGAAGAAGATCGCCGATGACCGCCAGGTGCGCGTTCCCGATGACGTGGT
GGAGTACATCATGGTCACCACCAGCCGCGAGGTAGGCGAGCTGATCGGTTTCTTCGAGACCATCTACCGCTTTTCCCTGG
CCCACAAGCGCAGGATCACCCTGGCGCTGGCCAGGGAGGCTCGCGAATGTGTTGCCTCGGGAGCCTCCTGA

Upstream 100 bases:

>100_bases
TCCTCAACCGCACCCCCCGCGGACGGGTGGCCACCCTTGCCGCCTACGAGCACTTTGGCCGCTCCGTTCCCGCCGCCCCC
CAGGCGGCCCTGTTGTGACC

Downstream 100 bases:

>100_bases
CATGGGTCCGTTTCACAATCGTCTCAAGACCCCGGAAGAGATCGAGCTGGAGCGGAAGCGGGAGGAGCTGTCCCGCCTGC
AGCGCCAACAGACTGAGCTG

Product: chromosomal replication initiator, DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MQQILEFPVSSSCTFDSFVVCDGNAAAVRFARRITDESEPERLLYLHGPPGSGKTHLLRAIALELAGGNPDQAPYLSCRD
VRSARSLVDRFHGAQGLVVDDLQLLPDSQDLRAALWQLFNDFHEAGRAVVLAGLHPPRMLPHLDDHLVSRLLWGLVARVD
ASDDLSRRMILKKIADDRQVRVPDDVVEYIMVTTSREVGELIGFFETIYRFSLAHKRRITLALAREARECVASGAS

Sequences:

>Translated_236_residues
MQQILEFPVSSSCTFDSFVVCDGNAAAVRFARRITDESEPERLLYLHGPPGSGKTHLLRAIALELAGGNPDQAPYLSCRD
VRSARSLVDRFHGAQGLVVDDLQLLPDSQDLRAALWQLFNDFHEAGRAVVLAGLHPPRMLPHLDDHLVSRLLWGLVARVD
ASDDLSRRMILKKIADDRQVRVPDDVVEYIMVTTSREVGELIGFFETIYRFSLAHKRRITLALAREARECVASGAS
>Mature_236_residues
MQQILEFPVSSSCTFDSFVVCDGNAAAVRFARRITDESEPERLLYLHGPPGSGKTHLLRAIALELAGGNPDQAPYLSCRD
VRSARSLVDRFHGAQGLVVDDLQLLPDSQDLRAALWQLFNDFHEAGRAVVLAGLHPPRMLPHLDDHLVSRLLWGLVARVD
ASDDLSRRMILKKIADDRQVRVPDDVVEYIMVTTSREVGELIGFFETIYRFSLAHKRRITLALAREARECVASGAS

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=232, Percent_Identity=26.7241379310345, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI226510964, Length=216, Percent_Identity=25, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 26299; Mature: 26299

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQILEFPVSSSCTFDSFVVCDGNAAAVRFARRITDESEPERLLYLHGPPGSGKTHLLRA
CCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHH
IALELAGGNPDQAPYLSCRDVRSARSLVDRFHGAQGLVVDDLQLLPDSQDLRAALWQLFN
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCHHHHHHHHHHHH
DFHEAGRAVVLAGLHPPRMLPHLDDHLVSRLLWGLVARVDASDDLSRRMILKKIADDRQV
HHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
RVPDDVVEYIMVTTSREVGELIGFFETIYRFSLAHKRRITLALAREARECVASGAS
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQILEFPVSSSCTFDSFVVCDGNAAAVRFARRITDESEPERLLYLHGPPGSGKTHLLRA
CCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHH
IALELAGGNPDQAPYLSCRDVRSARSLVDRFHGAQGLVVDDLQLLPDSQDLRAALWQLFN
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCHHHHHHHHHHHH
DFHEAGRAVVLAGLHPPRMLPHLDDHLVSRLLWGLVARVDASDDLSRRMILKKIADDRQV
HHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
RVPDDVVEYIMVTTSREVGELIGFFETIYRFSLAHKRRITLALAREARECVASGAS
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA