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The map label for this gene is pdxJ

Identifier: 118580672

GI number: 118580672

Start: 2437456

End: 2438175

Strand: Direct

Name: pdxJ

Synonym: Ppro_2257

Alternate gene names: 118580672

Gene position: 2437456-2438175 (Clockwise)

Preceding gene: 118580671

Following gene: 118580673

Centisome position: 60.81

GC content: 64.72

Gene sequence:

>720_bases
ATGGCAAAACTGGGACTCAACGTCGATCATGTGGCCACCGTGCGCCAGGCGCGCGGCGGCATGGAGCCGGATCCGGTCAC
GGCGGCCGCCCTGGGCGAGCTTGCCGGCGCCGAAGGAATCACCATCCACCTGCGGGAGGACCGCCGTCACATCCAGGACC
GCGACCTGGAGATCCTGCGACGCACCGTCAAGACAAAGCTCAACCTGGAAATGGCGGCAACCCAGGAGATGGTGCGCATC
GCCCTGAGGACCAAGCCGGAGCAGGTCACCCTGGTGCCGGAGAAACGGCAGGAGCTGACCACCGAGGGGGGGCTGGACGT
GATCCTCAACCTGAAGGCCATCACCGACGCGGTCAAGCGCCTGCGGGACGGCGGCATTGTGGTCAGCCTGTTCGTGGACC
CGGACCAGGAGCAGATCAAGGCCGCCAACAAGAGCGGCGCCGACTACATCGAGATTCACACCGGCGCCTATGCCGACGCT
CCAGACTGGCCCTCCCAGAAGCGGCAACTGGAGGAGATCGACGCGGCCATCAAGCTGGCCAGCAAGGTCGGCATGGGGGT
CAACGCCGGACATGGCATCAACTACGTCAACATCAAGCCGCTGGCAGCCCTGGGGGGCATCGAGGAGTACAACATCGGCC
ACTCCATCATGGCCCGCGCCATACTGGTGGGCATGGACCGTGCCGTGAAGGACATGGTCGAGCTGATCAAATACGCATGA

Upstream 100 bases:

>100_bases
CCTACGAGATCACCGCCTGGGCCAACGAGATCATCGACCTGGTCAGGAAGCACCTGGGAGAAAAGCAGTAACCCCGCCGG
ATTCGCAAGGAGACGAGAAC

Downstream 100 bases:

>100_bases
TCATCGGCATCGGCACCGACATCGTCGGCATCCCCCGTTTCCAGCGTCATGTGGACGACCCCGACAGTTCTCTCCTGCGA
CGCATCTTTACTGACCAGGA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MAKLGLNVDHVATVRQARGGMEPDPVTAAALGELAGAEGITIHLREDRRHIQDRDLEILRRTVKTKLNLEMAATQEMVRI
ALRTKPEQVTLVPEKRQELTTEGGLDVILNLKAITDAVKRLRDGGIVVSLFVDPDQEQIKAANKSGADYIEIHTGAYADA
PDWPSQKRQLEEIDAAIKLASKVGMGVNAGHGINYVNIKPLAALGGIEEYNIGHSIMARAILVGMDRAVKDMVELIKYA

Sequences:

>Translated_239_residues
MAKLGLNVDHVATVRQARGGMEPDPVTAAALGELAGAEGITIHLREDRRHIQDRDLEILRRTVKTKLNLEMAATQEMVRI
ALRTKPEQVTLVPEKRQELTTEGGLDVILNLKAITDAVKRLRDGGIVVSLFVDPDQEQIKAANKSGADYIEIHTGAYADA
PDWPSQKRQLEEIDAAIKLASKVGMGVNAGHGINYVNIKPLAALGGIEEYNIGHSIMARAILVGMDRAVKDMVELIKYA
>Mature_238_residues
AKLGLNVDHVATVRQARGGMEPDPVTAAALGELAGAEGITIHLREDRRHIQDRDLEILRRTVKTKLNLEMAATQEMVRIA
LRTKPEQVTLVPEKRQELTTEGGLDVILNLKAITDAVKRLRDGGIVVSLFVDPDQEQIKAANKSGADYIEIHTGAYADAP
DWPSQKRQLEEIDAAIKLASKVGMGVNAGHGINYVNIKPLAALGGIEEYNIGHSIMARAILVGMDRAVKDMVELIKYA

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=233, Percent_Identity=56.6523605150215, Blast_Score=269, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_PELPD (A1AR94)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901922.1
- ProteinModelPortal:   A1AR94
- SMR:   A1AR94
- STRING:   A1AR94
- GeneID:   4574981
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2257
- eggNOG:   COG0854
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- PhylomeDB:   A1AR94
- ProtClustDB:   PRK05265
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 26071; Mature: 25939

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: ACT_SITE 43-43 ACT_SITE 70-70 ACT_SITE 191-191 BINDING 7-7 BINDING 18-18 BINDING 45-45 BINDING 50-50 BINDING 100-100 BINDING 192-192

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLGLNVDHVATVRQARGGMEPDPVTAAALGELAGAEGITIHLREDRRHIQDRDLEILR
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHH
RTVKTKLNLEMAATQEMVRIALRTKPEQVTLVPEKRQELTTEGGLDVILNLKAITDAVKR
HHHHHHHCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCEEEEEHHHHHHHHHH
LRDGGIVVSLFVDPDQEQIKAANKSGADYIEIHTGAYADAPDWPSQKRQLEEIDAAIKLA
HCCCCEEEEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
SKVGMGVNAGHGINYVNIKPLAALGGIEEYNIGHSIMARAILVGMDRAVKDMVELIKYA
HHHCCCCCCCCCCCEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKLGLNVDHVATVRQARGGMEPDPVTAAALGELAGAEGITIHLREDRRHIQDRDLEILR
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHH
RTVKTKLNLEMAATQEMVRIALRTKPEQVTLVPEKRQELTTEGGLDVILNLKAITDAVKR
HHHHHHHCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCEEEEEHHHHHHHHHH
LRDGGIVVSLFVDPDQEQIKAANKSGADYIEIHTGAYADAPDWPSQKRQLEEIDAAIKLA
HCCCCEEEEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
SKVGMGVNAGHGINYVNIKPLAALGGIEEYNIGHSIMARAILVGMDRAVKDMVELIKYA
HHHCCCCCCCCCCCEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA