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The map label for this gene is acpS

Identifier: 118580673

GI number: 118580673

Start: 2438172

End: 2438555

Strand: Direct

Name: acpS

Synonym: Ppro_2258

Alternate gene names: 118580673

Gene position: 2438172-2438555 (Clockwise)

Preceding gene: 118580672

Following gene: 118580674

Centisome position: 60.83

GC content: 63.02

Gene sequence:

>384_bases
ATGATCATCGGCATCGGCACCGACATCGTCGGCATCCCCCGTTTCCAGCGTCATGTGGACGACCCCGACAGTTCTCTCCT
GCGACGCATCTTTACTGACCAGGAACGAAGCTACTGCAACGCCCGGAAGAGCGGCGCTGCCGCCTGTTTCGCCGCCCGCT
TCGCCGCCAAGGAATCCTTCCTCAAGGCCCTGGGAACCGGGCTGAGCGACGGCATATCCTGGCATGACATGGAGGTGGTC
AACGACGAGCTGGGCAAGCCGGAGCTGCGCCTCTCCCGCAGGGCGGAGGAGCTATTCCGGAAAAAGAAGGGGGCAGGCCT
GTTCCTCTCCCTCTCCCATGACGGCGGCTGTGCCGTTGCCATGGTGGTTCTGGAGTCCCTATGA

Upstream 100 bases:

>100_bases
GCATCGAGGAGTACAACATCGGCCACTCCATCATGGCCCGCGCCATACTGGTGGGCATGGACCGTGCCGTGAAGGACATG
GTCGAGCTGATCAAATACGC

Downstream 100 bases:

>100_bases
AAATCGTCATGTCACAGACCATGCAGGAGATGGACAGACGGACCATGGAGGAGTACGGCATCCCCGGTCTCGTTCTGATG
GAGAACGCAGGACGCTGCTG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MIIGIGTDIVGIPRFQRHVDDPDSSLLRRIFTDQERSYCNARKSGAAACFAARFAAKESFLKALGTGLSDGISWHDMEVV
NDELGKPELRLSRRAEELFRKKKGAGLFLSLSHDGGCAVAMVVLESL

Sequences:

>Translated_127_residues
MIIGIGTDIVGIPRFQRHVDDPDSSLLRRIFTDQERSYCNARKSGAAACFAARFAAKESFLKALGTGLSDGISWHDMEVV
NDELGKPELRLSRRAEELFRKKKGAGLFLSLSHDGGCAVAMVVLESL
>Mature_127_residues
MIIGIGTDIVGIPRFQRHVDDPDSSLLRRIFTDQERSYCNARKSGAAACFAARFAAKESFLKALGTGLSDGISWHDMEVV
NDELGKPELRLSRRAEELFRKKKGAGLFLSLSHDGGCAVAMVVLESL

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=125, Percent_Identity=38.4, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_PELPD (A1AR95)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901923.1
- ProteinModelPortal:   A1AR95
- SMR:   A1AR95
- STRING:   A1AR95
- GeneID:   4574982
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2258
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   NSSAIAY
- PhylomeDB:   A1AR95
- ProtClustDB:   PRK14656
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13912; Mature: 13912

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGIGTDIVGIPRFQRHVDDPDSSLLRRIFTDQERSYCNARKSGAAACFAARFAAKESF
CEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LKALGTGLSDGISWHDMEVVNDELGKPELRLSRRAEELFRKKKGAGLFLSLSHDGGCAVA
HHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
MVVLESL
HHHHHHC
>Mature Secondary Structure
MIIGIGTDIVGIPRFQRHVDDPDSSLLRRIFTDQERSYCNARKSGAAACFAARFAAKESF
CEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LKALGTGLSDGISWHDMEVVNDELGKPELRLSRRAEELFRKKKGAGLFLSLSHDGGCAVA
HHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
MVVLESL
HHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA