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The map label for this gene is corA [H]

Identifier: 118580659

GI number: 118580659

Start: 2424327

End: 2425400

Strand: Direct

Name: corA [H]

Synonym: Ppro_2244

Alternate gene names: 118580659

Gene position: 2424327-2425400 (Clockwise)

Preceding gene: 118580658

Following gene: 118580660

Centisome position: 60.49

GC content: 61.45

Gene sequence:

>1074_bases
GTGCGGCGAAGAAGCTACTACCGCGGCCAGTCGCGCAAGGCCGGCCTTCCTCCCGGCACCCTGGTACACACCGGCGCCCT
GCCCACCACCGGGGCCACCACCGTCAGCGCCATCAGCTATTCGACAGAGGATTTCCGCGAATATCATCCGCAGAACCTGG
ACCAATGCATTCCGGTCAAGGGGACCGGCAAGATCACCTGGATCAACCTGGAGGGGCTTCACGACCTGGAGCTGATCAGG
CACTTCGGCGACTGCTACGGACTGCACCCCCTGATCCTGGAGGATCTCGTCAACACCAGCCAGCGCCCCAAGCTGGAGGA
TTACGGGGATTACCTCTTCATCGTCACCCGCATGATCCGCTTCCAGAAGGATCGGGGCATCGAGACGGAACAGGTGGCCA
TGATCCTCGGCCCCGGCTACCTGCTCTCCTTCCAGGAGGGGATCGTTGGAGACGCGTTCGAATCGGTGCGGGAGCGGATC
CGCTCCGGCCGGGGACGCCTCAGGTCCCTGGGGGCCGACTATCTGACCTACGCCCTGATGGATGCCATCGTGGACGGCTA
TTTCACCGTGCTGGAGGAGATGGGGGAATATCTGGAGGACCTGGAGGAGGAGCTTGCCCAGGGGCCGACGCAGATGATCC
TGAAACGGATCATCGCACTCAAGCGGGAGATCATCTTCATGCGCAAGAGCGCCTGGCCGCTGCGGGAGGTGACCTCTGCC
CTGGAGCGGGGTGAGTCGCAGTTGATCGGCGACCCGTCCCGTGTCTACTTCCGCGACATCTACGACCACAGCATCCAGGT
GATCGATGGGGTGGAGACCTTCCGCGACCTGCTCTCCGGCATGCTGGACCTGTACCTCTCCAGCATCGGCAACCGGACCA
ACGAGGTGATGAAGTTTTTGACCGTGATCGGCACGATCTTCCTGCCACTGACCTTCCTGGTGGGGGTATACGGCATGAAC
TTCAAGCACATTCCGGAACTCTCATGGCCCAACGGCTACTTCGAGTTGTGGGGGGTGATGCTGGCCATCTCCCTGGGCAT
GGTGCTCTATTTCAAAAGAAAGCGGTGGCTCTAA

Upstream 100 bases:

>100_bases
TTCACCTGGCTGATGAACCGGTGCATCGTGGCCCCCCGCCTGAAGCGGATATTCGACTATCGACGCGACGCCCTGCAGCG
GATCTTCCCGGCAGGCTGAC

Downstream 100 bases:

>100_bases
CCACTTGGTGACGACATGAAACAACTGCTGCTCAGATGGGTTTTGAATTCCTTTGCCCTGTTCTTCGTGATGAAACTGAT
TCCCGGCATCCAGATCGACC

Product: magnesium and cobalt transport protein CorA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRRRSYYRGQSRKAGLPPGTLVHTGALPTTGATTVSAISYSTEDFREYHPQNLDQCIPVKGTGKITWINLEGLHDLELIR
HFGDCYGLHPLILEDLVNTSQRPKLEDYGDYLFIVTRMIRFQKDRGIETEQVAMILGPGYLLSFQEGIVGDAFESVRERI
RSGRGRLRSLGADYLTYALMDAIVDGYFTVLEEMGEYLEDLEEELAQGPTQMILKRIIALKREIIFMRKSAWPLREVTSA
LERGESQLIGDPSRVYFRDIYDHSIQVIDGVETFRDLLSGMLDLYLSSIGNRTNEVMKFLTVIGTIFLPLTFLVGVYGMN
FKHIPELSWPNGYFELWGVMLAISLGMVLYFKRKRWL

Sequences:

>Translated_357_residues
MRRRSYYRGQSRKAGLPPGTLVHTGALPTTGATTVSAISYSTEDFREYHPQNLDQCIPVKGTGKITWINLEGLHDLELIR
HFGDCYGLHPLILEDLVNTSQRPKLEDYGDYLFIVTRMIRFQKDRGIETEQVAMILGPGYLLSFQEGIVGDAFESVRERI
RSGRGRLRSLGADYLTYALMDAIVDGYFTVLEEMGEYLEDLEEELAQGPTQMILKRIIALKREIIFMRKSAWPLREVTSA
LERGESQLIGDPSRVYFRDIYDHSIQVIDGVETFRDLLSGMLDLYLSSIGNRTNEVMKFLTVIGTIFLPLTFLVGVYGMN
FKHIPELSWPNGYFELWGVMLAISLGMVLYFKRKRWL
>Mature_357_residues
MRRRSYYRGQSRKAGLPPGTLVHTGALPTTGATTVSAISYSTEDFREYHPQNLDQCIPVKGTGKITWINLEGLHDLELIR
HFGDCYGLHPLILEDLVNTSQRPKLEDYGDYLFIVTRMIRFQKDRGIETEQVAMILGPGYLLSFQEGIVGDAFESVRERI
RSGRGRLRSLGADYLTYALMDAIVDGYFTVLEEMGEYLEDLEEELAQGPTQMILKRIIALKREIIFMRKSAWPLREVTSA
LERGESQLIGDPSRVYFRDIYDHSIQVIDGVETFRDLLSGMLDLYLSSIGNRTNEVMKFLTVIGTIFLPLTFLVGVYGMN
FKHIPELSWPNGYFELWGVMLAISLGMVLYFKRKRWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI1787604, Length=269, Percent_Identity=23.7918215613383, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367297, Length=69, Percent_Identity=42.0289855072464, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 40878; Mature: 40878

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRSYYRGQSRKAGLPPGTLVHTGALPTTGATTVSAISYSTEDFREYHPQNLDQCIPVK
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCCC
GTGKITWINLEGLHDLELIRHFGDCYGLHPLILEDLVNTSQRPKLEDYGDYLFIVTRMIR
CCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
FQKDRGIETEQVAMILGPGYLLSFQEGIVGDAFESVRERIRSGRGRLRSLGADYLTYALM
HHHHCCCCHHHEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAIVDGYFTVLEEMGEYLEDLEEELAQGPTQMILKRIIALKREIIFMRKSAWPLREVTSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LERGESQLIGDPSRVYFRDIYDHSIQVIDGVETFRDLLSGMLDLYLSSIGNRTNEVMKFL
HHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TVIGTIFLPLTFLVGVYGMNFKHIPELSWPNGYFELWGVMLAISLGMVLYFKRKRWL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRRSYYRGQSRKAGLPPGTLVHTGALPTTGATTVSAISYSTEDFREYHPQNLDQCIPVK
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCCC
GTGKITWINLEGLHDLELIRHFGDCYGLHPLILEDLVNTSQRPKLEDYGDYLFIVTRMIR
CCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
FQKDRGIETEQVAMILGPGYLLSFQEGIVGDAFESVRERIRSGRGRLRSLGADYLTYALM
HHHHCCCCHHHEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAIVDGYFTVLEEMGEYLEDLEEELAQGPTQMILKRIIALKREIIFMRKSAWPLREVTSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LERGESQLIGDPSRVYFRDIYDHSIQVIDGVETFRDLLSGMLDLYLSSIGNRTNEVMKFL
HHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TVIGTIFLPLTFLVGVYGMNFKHIPELSWPNGYFELWGVMLAISLGMVLYFKRKRWL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]