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The map label for this gene is aspC [H]

Identifier: 118580605

GI number: 118580605

Start: 2361624

End: 2362817

Strand: Reverse

Name: aspC [H]

Synonym: Ppro_2189

Alternate gene names: 118580605

Gene position: 2362817-2361624 (Counterclockwise)

Preceding gene: 118580606

Following gene: 118580604

Centisome position: 58.95

GC content: 59.38

Gene sequence:

>1194_bases
ATGAAATTAGCGGATCGCGTGCACAGAATCCAACCATCACCCACGCTTGCCATAGATGCAAAAGCAAAGGCCCTCAAGGC
TCAAGGAGTCGATGTGATCAGTTTCGGCGCCGGAGAGCCTGACTTCGACACCCCCGACGCCATCAGGGATGCGGCCAGGA
ACGCCATCGACTCCGGTTTCACCAGGTACATGCCGGTGGGAGGCGCCGACGACCTGAAGGACGCCATCATCCTCAAGATG
AAGCGGGACCACGGTATCGAATACAGCCGTGCCGAGATCTGCGTCTCCTGCGGCGCCAAGCACAGCCTGTACAATATCTC
CCAGGCCCTGATCCAGGAAGGGGACGAGGTCATCATCCCGGCCCCCTACTGGGTCTCCTATCCCGATCAGGTGGTGCTGG
CCGGCGGGACACCGATTTTTATCCAGACCGATGAGAAGTCGGATTTCAAGATCACCCCCCGGCAGTTGGAAGCGGCCATC
ACCCCCCGCACCAAGGCCATGATTCTCAACTCCCCCTGCAACCCCACCGGCACCAGCTACACCGGGGAAGAGCTGCGGGC
CATCGCCCAGGTCTGCCTCGCCCATGACTTCATCATCATCTCCGACGACATCTACGAGCGGCTGATCTACGACGGTCAGG
TTTTCAGCAACATCGTCCAGGTGGCACCGGAACTGAAGCAGCGGGTTGTCCTGGTTAACGGCGTGTCCAAGACCTACGCC
ATGACCGGCTGGCGCATCGGCTACGCCTGCGGCCCGCAGGAACTGATCGCCGCCATGACCAAGATGCAGTCCCAGTCAAC
TTCCAACGCCTGTTCCATAGCCCAGAAGGCTTCCGTCGAGGCCATTGCCGGTTCCCAGGAAAAGGTGACCGCCATGGTTC
AGGAATTTGAAAAACGCCGTACCTATATCGTGCAGCGGTTGAATGCCATGCCGGGAGTCACCTGCTTCAATTCCACCGGC
GCCTTCTATGCCTTCCCCAACTTTTCCGCCCTCTATGGCAAGAGCTTCAACGGAAAGATCATTGCCAGCTCCACCGATCT
AGCCGATTATCTGCTGGAGGAGGCCAAGGTGGCGTTGGTTCCGGGGGTCGCCTTTGGCGACGACAGGTATGCCCGGCTCT
CCTATGCCATCGGCCTGGAGAGTATCGCCGAGGGCATGGATCGTCTCGAACGGGCGATCCAGAACCTGAAATAG

Upstream 100 bases:

>100_bases
GCGCCCTCAGATTGAAATACGGCCTGGACTGATGGCCGAAAAAAAGCATAACCGCGCGGGGAGGATGAATCGCGGTTAGT
GAGTCAGCAAAGGAACTTTC

Downstream 100 bases:

>100_bases
CAGCCTCGCGCGGAGACGCCATCGGCGTCTCCGCGCTACCGTACTGTTGCATGCATGCCAGGGGGAAACATGATTACCAG
GGATATGATTATCGCCGATA

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKLADRVHRIQPSPTLAIDAKAKALKAQGVDVISFGAGEPDFDTPDAIRDAARNAIDSGFTRYMPVGGADDLKDAIILKM
KRDHGIEYSRAEICVSCGAKHSLYNISQALIQEGDEVIIPAPYWVSYPDQVVLAGGTPIFIQTDEKSDFKITPRQLEAAI
TPRTKAMILNSPCNPTGTSYTGEELRAIAQVCLAHDFIIISDDIYERLIYDGQVFSNIVQVAPELKQRVVLVNGVSKTYA
MTGWRIGYACGPQELIAAMTKMQSQSTSNACSIAQKASVEAIAGSQEKVTAMVQEFEKRRTYIVQRLNAMPGVTCFNSTG
AFYAFPNFSALYGKSFNGKIIASSTDLADYLLEEAKVALVPGVAFGDDRYARLSYAIGLESIAEGMDRLERAIQNLK

Sequences:

>Translated_397_residues
MKLADRVHRIQPSPTLAIDAKAKALKAQGVDVISFGAGEPDFDTPDAIRDAARNAIDSGFTRYMPVGGADDLKDAIILKM
KRDHGIEYSRAEICVSCGAKHSLYNISQALIQEGDEVIIPAPYWVSYPDQVVLAGGTPIFIQTDEKSDFKITPRQLEAAI
TPRTKAMILNSPCNPTGTSYTGEELRAIAQVCLAHDFIIISDDIYERLIYDGQVFSNIVQVAPELKQRVVLVNGVSKTYA
MTGWRIGYACGPQELIAAMTKMQSQSTSNACSIAQKASVEAIAGSQEKVTAMVQEFEKRRTYIVQRLNAMPGVTCFNSTG
AFYAFPNFSALYGKSFNGKIIASSTDLADYLLEEAKVALVPGVAFGDDRYARLSYAIGLESIAEGMDRLERAIQNLK
>Mature_397_residues
MKLADRVHRIQPSPTLAIDAKAKALKAQGVDVISFGAGEPDFDTPDAIRDAARNAIDSGFTRYMPVGGADDLKDAIILKM
KRDHGIEYSRAEICVSCGAKHSLYNISQALIQEGDEVIIPAPYWVSYPDQVVLAGGTPIFIQTDEKSDFKITPRQLEAAI
TPRTKAMILNSPCNPTGTSYTGEELRAIAQVCLAHDFIIISDDIYERLIYDGQVFSNIVQVAPELKQRVVLVNGVSKTYA
MTGWRIGYACGPQELIAAMTKMQSQSTSNACSIAQKASVEAIAGSQEKVTAMVQEFEKRRTYIVQRLNAMPGVTCFNSTG
AFYAFPNFSALYGKSFNGKIIASSTDLADYLLEEAKVALVPGVAFGDDRYARLSYAIGLESIAEGMDRLERAIQNLK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=319, Percent_Identity=31.3479623824451, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI56713256, Length=319, Percent_Identity=31.3479623824451, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI95147551, Length=293, Percent_Identity=30.3754266211604, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI169881279, Length=293, Percent_Identity=30.3754266211604, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI169881281, Length=267, Percent_Identity=27.3408239700375, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI4507369, Length=394, Percent_Identity=20.5583756345178, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786816, Length=370, Percent_Identity=27.027027027027, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788627, Length=358, Percent_Identity=31.5642458100559, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788722, Length=403, Percent_Identity=28.7841191066998, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17567369, Length=393, Percent_Identity=26.4631043256997, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=281, Percent_Identity=26.6903914590747, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=281, Percent_Identity=27.0462633451957, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=343, Percent_Identity=25.3644314868805, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71981209, Length=320, Percent_Identity=23.4375, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=392, Percent_Identity=25.5102040816327, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6323118, Length=378, Percent_Identity=21.6931216931217, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320317, Length=358, Percent_Identity=21.2290502793296, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28573069, Length=260, Percent_Identity=28.0769230769231, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646114, Length=260, Percent_Identity=28.0769230769231, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573067, Length=260, Percent_Identity=28.0769230769231, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573065, Length=260, Percent_Identity=28.0769230769231, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18859735, Length=228, Percent_Identity=24.5614035087719, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43307; Mature: 43307

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLADRVHRIQPSPTLAIDAKAKALKAQGVDVISFGAGEPDFDTPDAIRDAARNAIDSGF
CCHHHHHHHCCCCCCEEEECHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TRYMPVGGADDLKDAIILKMKRDHGIEYSRAEICVSCGAKHSLYNISQALIQEGDEVIIP
CEEECCCCCCHHCCCEEEEEHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEE
APYWVSYPDQVVLAGGTPIFIQTDEKSDFKITPRQLEAAITPRTKAMILNSPCNPTGTSY
CCCEECCCCCEEEECCCEEEEEECCCCCCEECHHHHHHHCCCCCEEEEEECCCCCCCCCC
TGEELRAIAQVCLAHDFIIISDDIYERLIYDGQVFSNIVQVAPELKQRVVLVNGVSKTYA
CHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCHHHE
MTGWRIGYACGPQELIAAMTKMQSQSTSNACSIAQKASVEAIAGSQEKVTAMVQEFEKRR
ECCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TYIVQRLNAMPGVTCFNSTGAFYAFPNFSALYGKSFNGKIIASSTDLADYLLEEAKVALV
HHHHHHHHCCCCCEEECCCCCEEECCCCHHHHCCCCCCEEEECCCHHHHHHHHHCCEEEE
PGVAFGDDRYARLSYAIGLESIAEGMDRLERAIQNLK
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLADRVHRIQPSPTLAIDAKAKALKAQGVDVISFGAGEPDFDTPDAIRDAARNAIDSGF
CCHHHHHHHCCCCCCEEEECHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TRYMPVGGADDLKDAIILKMKRDHGIEYSRAEICVSCGAKHSLYNISQALIQEGDEVIIP
CEEECCCCCCHHCCCEEEEEHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEE
APYWVSYPDQVVLAGGTPIFIQTDEKSDFKITPRQLEAAITPRTKAMILNSPCNPTGTSY
CCCEECCCCCEEEECCCEEEEEECCCCCCEECHHHHHHHCCCCCEEEEEECCCCCCCCCC
TGEELRAIAQVCLAHDFIIISDDIYERLIYDGQVFSNIVQVAPELKQRVVLVNGVSKTYA
CHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCHHHE
MTGWRIGYACGPQELIAAMTKMQSQSTSNACSIAQKASVEAIAGSQEKVTAMVQEFEKRR
ECCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TYIVQRLNAMPGVTCFNSTGAFYAFPNFSALYGKSFNGKIIASSTDLADYLLEEAKVALV
HHHHHHHHCCCCCEEECCCCCEEECCCCHHHHCCCCCCEEEECCCHHHHHHHHHCCEEEE
PGVAFGDDRYARLSYAIGLESIAEGMDRLERAIQNLK
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8837436 [H]