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The map label for this gene is coaD [H]

Identifier: 118580606

GI number: 118580606

Start: 2362886

End: 2363368

Strand: Reverse

Name: coaD [H]

Synonym: Ppro_2190

Alternate gene names: 118580606

Gene position: 2363368-2362886 (Counterclockwise)

Preceding gene: 118580607

Following gene: 118580605

Centisome position: 58.97

GC content: 52.17

Gene sequence:

>483_bases
ATGAAGAAAATTGCCGTGTATCCCGGTTCGTTCGATCCGATCACCTATGGCCACCTGGACATCATCAACCGTGGGCTGAA
GGTCTTTGACGAGATTATCGTCGCGGTTGCCTGCAATTCGCAGAAAAAGTCGCTGTTCAGCATCGAGGAGCGCATGGCTC
TGATCAGGCGGGTCGTTGACCAGGACCGTGTCAGGGTTGACACTTTTACCGGTCTTCTGATAGATTACGTGACTCGCCAG
AACGCGGATGTGATCATTCGCGGACTGCGCGCAATCTCGGATTTTGAATACGAATTCCAGATCGCCCAGATGAACAGCAG
CCTGGGTCATGACATAGAAACACTGTTCATGATGACATCGTTGCAGTACGGCTACCTCTCCTCTTCCATTGTCAAGGAAG
TCTGCGGTTTACGGGGAAATATCGACGGCTTCGTTCCCCCTGAGGTGAAGAGCGCCCTCAGATTGAAATACGGCCTGGAC
TGA

Upstream 100 bases:

>100_bases
CGGCCCGTGCCATTCTGCCGGAGCGCGAGGGATGTCTTGTCAGGAGTGATCGGCGGGTATACGGCGATACTGCGTTGGCA
TTGTACGTTTTGGGGGAAGA

Downstream 100 bases:

>100_bases
TGGCCGAAAAAAAGCATAACCGCGCGGGGAGGATGAATCGCGGTTAGTGAGTCAGCAAAGGAACTTTCATGAAATTAGCG
GATCGCGTGCACAGAATCCA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKKIAVYPGSFDPITYGHLDIINRGLKVFDEIIVAVACNSQKKSLFSIEERMALIRRVVDQDRVRVDTFTGLLIDYVTRQ
NADVIIRGLRAISDFEYEFQIAQMNSSLGHDIETLFMMTSLQYGYLSSSIVKEVCGLRGNIDGFVPPEVKSALRLKYGLD

Sequences:

>Translated_160_residues
MKKIAVYPGSFDPITYGHLDIINRGLKVFDEIIVAVACNSQKKSLFSIEERMALIRRVVDQDRVRVDTFTGLLIDYVTRQ
NADVIIRGLRAISDFEYEFQIAQMNSSLGHDIETLFMMTSLQYGYLSSSIVKEVCGLRGNIDGFVPPEVKSALRLKYGLD
>Mature_160_residues
MKKIAVYPGSFDPITYGHLDIINRGLKVFDEIIVAVACNSQKKSLFSIEERMALIRRVVDQDRVRVDTFTGLLIDYVTRQ
NADVIIRGLRAISDFEYEFQIAQMNSSLGHDIETLFMMTSLQYGYLSSSIVKEVCGLRGNIDGFVPPEVKSALRLKYGLD

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=44.0251572327044, Blast_Score=156, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18103; Mature: 18103

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAVYPGSFDPITYGHLDIINRGLKVFDEIIVAVACNSQKKSLFSIEERMALIRRVVD
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QDRVRVDTFTGLLIDYVTRQNADVIIRGLRAISDFEYEFQIAQMNSSLGHDIETLFMMTS
HHHEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEEHHHHCCCCCCHHHHHHHHHH
LQYGYLSSSIVKEVCGLRGNIDGFVPPEVKSALRLKYGLD
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKIAVYPGSFDPITYGHLDIINRGLKVFDEIIVAVACNSQKKSLFSIEERMALIRRVVD
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
QDRVRVDTFTGLLIDYVTRQNADVIIRGLRAISDFEYEFQIAQMNSSLGHDIETLFMMTS
HHHEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEEEHHHHCCCCCCHHHHHHHHHH
LQYGYLSSSIVKEVCGLRGNIDGFVPPEVKSALRLKYGLD
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA