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The map label for this gene is rmlC [H]

Identifier: 118580534

GI number: 118580534

Start: 2277761

End: 2278306

Strand: Direct

Name: rmlC [H]

Synonym: Ppro_2118

Alternate gene names: 118580534

Gene position: 2277761-2278306 (Clockwise)

Preceding gene: 118580532

Following gene: 118580535

Centisome position: 56.83

GC content: 61.17

Gene sequence:

>546_bases
ATGACCATTATTCCCACCAGCATCCCCGATGTGCTGATCGTCGAACCGAAGGTGTTCGGAGACGAGCGCGGCTTTTTCTT
CGAGAGTTTCAACCAGCGCATCTGGCGCGAACTGACCGGTCTGGACGGCTGCTTTGTCCAGCACAACCACTCCCGATCAA
CAGCCGGAGTCCTGCGCGGTCTCCACTACCAGATCCACAATCCCCAGGGGAAGCTGGTGCGGGTCGTCAGCGGAGAGGTC
TTTGACGTGGCCGTGGATATCCGTCGAAGTTCCGCCACCTTCGGCCGCTGGTTCGGCGCCGCGCTTTCGGCGGATAACAA
GCGCCAACTGTGGGTACCGCCCGGTTTTGCCCACGGTTTCTACGTTACCTCCCCGGTTGCCGAATTCCTCTACCTGACCA
CCGACTTCTGGGCGCCGGAGCATGAACGCTGCATAGCCTGGAACGATCCGGACCTGGCCATCCAGTGGCCGCTTGCGGGA
GAACCGTCCCTGTCGGACAAAGACCGAGCAGCCCCCCCCTTCAGGAAAGCGGAACTCTTTCCCTGA

Upstream 100 bases:

>100_bases
CTGAATATTATTTGGTTTTAAACAAACGCTTGCAGGAAGCGCCGATATTTTGCTACTTACATGCAAGCATCTCCGAATAA
AAACAGCAGGATTTCACACC

Downstream 100 bases:

>100_bases
TCCGGACGACATCACGCAGCGGGATTACCCTGAGCAGCTCTGAAAAATAGACATTGCACCACGAACGAAACGTTTTTTGA
GGGATACACTCATTCCAGGG

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTIIPTSIPDVLIVEPKVFGDERGFFFESFNQRIWRELTGLDGCFVQHNHSRSTAGVLRGLHYQIHNPQGKLVRVVSGEV
FDVAVDIRRSSATFGRWFGAALSADNKRQLWVPPGFAHGFYVTSPVAEFLYLTTDFWAPEHERCIAWNDPDLAIQWPLAG
EPSLSDKDRAAPPFRKAELFP

Sequences:

>Translated_181_residues
MTIIPTSIPDVLIVEPKVFGDERGFFFESFNQRIWRELTGLDGCFVQHNHSRSTAGVLRGLHYQIHNPQGKLVRVVSGEV
FDVAVDIRRSSATFGRWFGAALSADNKRQLWVPPGFAHGFYVTSPVAEFLYLTTDFWAPEHERCIAWNDPDLAIQWPLAG
EPSLSDKDRAAPPFRKAELFP
>Mature_180_residues
TIIPTSIPDVLIVEPKVFGDERGFFFESFNQRIWRELTGLDGCFVQHNHSRSTAGVLRGLHYQIHNPQGKLVRVVSGEVF
DVAVDIRRSSATFGRWFGAALSADNKRQLWVPPGFAHGFYVTSPVAEFLYLTTDFWAPEHERCIAWNDPDLAIQWPLAGE
PSLSDKDRAAPPFRKAELFP

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=169, Percent_Identity=57.396449704142, Blast_Score=194, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17550412, Length=172, Percent_Identity=47.093023255814, Blast_Score=150, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20485; Mature: 20354

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIPTSIPDVLIVEPKVFGDERGFFFESFNQRIWRELTGLDGCFVQHNHSRSTAGVLRG
CEECCCCCCCEEEECCEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHC
LHYQIHNPQGKLVRVVSGEVFDVAVDIRRSSATFGRWFGAALSADNKRQLWVPPGFAHGF
CEEEEECCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCE
YVTSPVAEFLYLTTDFWAPEHERCIAWNDPDLAIQWPLAGEPSLSDKDRAAPPFRKAELF
EEHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
P
C
>Mature Secondary Structure 
TIIPTSIPDVLIVEPKVFGDERGFFFESFNQRIWRELTGLDGCFVQHNHSRSTAGVLRG
EECCCCCCCEEEECCEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHC
LHYQIHNPQGKLVRVVSGEVFDVAVDIRRSSATFGRWFGAALSADNKRQLWVPPGFAHGF
CEEEEECCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCE
YVTSPVAEFLYLTTDFWAPEHERCIAWNDPDLAIQWPLAGEPSLSDKDRAAPPFRKAELF
EEHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]