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The map label for this gene is rpfG [H]

Identifier: 118580535

GI number: 118580535

Start: 2278418

End: 2279584

Strand: Direct

Name: rpfG [H]

Synonym: Ppro_2119

Alternate gene names: 118580535

Gene position: 2278418-2279584 (Clockwise)

Preceding gene: 118580534

Following gene: 118580537

Centisome position: 56.85

GC content: 61.27

Gene sequence:

>1167_bases
ATGCCACGAGCACTGATTCCGCTGGCGGACGGATTTGAAGAGATAGAAGCCATGACCGTTGTCGATGTGCTGCGAAGGGC
CGGATTCGAGGTGGTACTGGCGGGCCTGCACGGCGGACCGGTGGAAAGCGTGCGCAGGGTCAGCGTCATCCCTGACGCAA
CCATCGACGCCGCACGTTCAGACCAGTTCGACATGGTCATCCTCCCGGGAGGGCAGCCGGGAGCCGCCAACCTGAGCGCC
GATGTCCGCGTCATCCGCCTGCTGAACGACTTCAGCAAGGACAACAAACTTATCGGCGCCATTTGCGCCGCCACCACGGT
GCTGTCGGAGGCGGGGTTGATCAGGGGAAAACGGGTCACCGCCTACCCTGACTACCGTGACAGGCTGCCCGGCGCACAGT
ACGAGGACAGCGCGGTAGTCATCGACGGCAAGATCATCACCAGCCAGGGACCGGGCACTGCCATGGCGTTTGCCCTGGCC
ATCGTATCCCGCTTTGCCGGTAAACACACTGCCGATGAAATCGCCGGCAAGATGCTGGTGCAGACCGATGACCGGCAGCA
CACCATCTGGGACAGGTACCTGTTCAACACCACGGTGCAATCCCTGGTGGAGGCGCTGGAACTGAAGGACAGCTTTACCC
AGGGACACGCCAAACGGGTCAGCGAGTACAGCCTGAGCATCGGGGCCAAGCTGAAACTGCCCCCCCTCGAGATGCGGAAC
CTCTACCTGGGGGCCATGCTCCACGACATCGGCAAGATCGCCACCGAGTCCGATCTGCTCACCAAGCCCGACAGCCTCAA
CCTGCGGGAGGAGACCCTGATGCGCGAGCACCCCATCAAGGGAACACTCTTCATCGTCGGCTTCGACAACATGAGCAACA
TCGTCCCCACCATCCTGCACCACCACGAACGCTGGGACGGCAGCGGTTATCCTGCCCGTCTGAAGGAGGAGCAGATCCCC
CTGCACGCCCGCATCGTCTGCCTTGCCGACGCCTTTGCCGCCATGCTCTTCCCGCGCTCTTTCCGGCCTGGCATGGAGAG
GGAACAGGCCATCCAGGAGATCCTTAAGCAGAAGGGAGCGCAATTCGACCCACACCTGGTCGACCTGTTCCTGGAGTGCC
TCACCGAATCACCCTTTGAAATGAATGATTTCAGTTTCTATTTCTAG

Upstream 100 bases:

>100_bases
TCACGCAGCGGGATTACCCTGAGCAGCTCTGAAAAATAGACATTGCACCACGAACGAAACGTTTTTTGAGGGATACACTC
ATTCCAGGGAGGGAACGGAT

Downstream 100 bases:

>100_bases
AAGTATCTTATTTTGTTGAGTTTATTTTTTGTCACCTCGAAAAAGGTAGCACATAGGTAACATTGGAACACAAAAGCCGC
CTCCCTAGGAGTCTGTCGGG

Product: metal dependent phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MPRALIPLADGFEEIEAMTVVDVLRRAGFEVVLAGLHGGPVESVRRVSVIPDATIDAARSDQFDMVILPGGQPGAANLSA
DVRVIRLLNDFSKDNKLIGAICAATTVLSEAGLIRGKRVTAYPDYRDRLPGAQYEDSAVVIDGKIITSQGPGTAMAFALA
IVSRFAGKHTADEIAGKMLVQTDDRQHTIWDRYLFNTTVQSLVEALELKDSFTQGHAKRVSEYSLSIGAKLKLPPLEMRN
LYLGAMLHDIGKIATESDLLTKPDSLNLREETLMREHPIKGTLFIVGFDNMSNIVPTILHHHERWDGSGYPARLKEEQIP
LHARIVCLADAFAAMLFPRSFRPGMEREQAIQEILKQKGAQFDPHLVDLFLECLTESPFEMNDFSFYF

Sequences:

>Translated_388_residues
MPRALIPLADGFEEIEAMTVVDVLRRAGFEVVLAGLHGGPVESVRRVSVIPDATIDAARSDQFDMVILPGGQPGAANLSA
DVRVIRLLNDFSKDNKLIGAICAATTVLSEAGLIRGKRVTAYPDYRDRLPGAQYEDSAVVIDGKIITSQGPGTAMAFALA
IVSRFAGKHTADEIAGKMLVQTDDRQHTIWDRYLFNTTVQSLVEALELKDSFTQGHAKRVSEYSLSIGAKLKLPPLEMRN
LYLGAMLHDIGKIATESDLLTKPDSLNLREETLMREHPIKGTLFIVGFDNMSNIVPTILHHHERWDGSGYPARLKEEQIP
LHARIVCLADAFAAMLFPRSFRPGMEREQAIQEILKQKGAQFDPHLVDLFLECLTESPFEMNDFSFYF
>Mature_387_residues
PRALIPLADGFEEIEAMTVVDVLRRAGFEVVLAGLHGGPVESVRRVSVIPDATIDAARSDQFDMVILPGGQPGAANLSAD
VRVIRLLNDFSKDNKLIGAICAATTVLSEAGLIRGKRVTAYPDYRDRLPGAQYEDSAVVIDGKIITSQGPGTAMAFALAI
VSRFAGKHTADEIAGKMLVQTDDRQHTIWDRYLFNTTVQSLVEALELKDSFTQGHAKRVSEYSLSIGAKLKLPPLEMRNL
YLGAMLHDIGKIATESDLLTKPDSLNLREETLMREHPIKGTLFIVGFDNMSNIVPTILHHHERWDGSGYPARLKEEQIPL
HARIVCLADAFAAMLFPRSFRPGMEREQAIQEILKQKGAQFDPHLVDLFLECLTESPFEMNDFSFYF

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG2206

COG function: function code T; HD-GYP domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=184, Percent_Identity=41.304347826087, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI31543380, Length=184, Percent_Identity=41.304347826087, Blast_Score=128, Evalue=8e-30,
Organism=Escherichia coli, GI87081736, Length=183, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082219, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17531319, Length=182, Percent_Identity=42.3076923076923, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17558714, Length=172, Percent_Identity=38.3720930232558, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571932, Length=180, Percent_Identity=44.4444444444444, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24653499, Length=182, Percent_Identity=42.3076923076923, Blast_Score=121, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 42975; Mature: 42844

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRALIPLADGFEEIEAMTVVDVLRRAGFEVVLAGLHGGPVESVRRVSVIPDATIDAARS
CCCCCCCHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHEEEECCCCCCCCCCC
DQFDMVILPGGQPGAANLSADVRVIRLLNDFSKDNKLIGAICAATTVLSEAGLIRGKRVT
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
AYPDYRDRLPGAQYEDSAVVIDGKIITSQGPGTAMAFALAIVSRFAGKHTADEIAGKMLV
ECCCHHHCCCCCCCCCCEEEEECEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHCEEEE
QTDDRQHTIWDRYLFNTTVQSLVEALELKDSFTQGHAKRVSEYSLSIGAKLKLPPLEMRN
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHH
LYLGAMLHDIGKIATESDLLTKPDSLNLREETLMREHPIKGTLFIVGFDNMSNIVPTILH
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHH
HHERWDGSGYPARLKEEQIPLHARIVCLADAFAAMLFPRSFRPGMEREQAIQEILKQKGA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC
QFDPHLVDLFLECLTESPFEMNDFSFYF
CCCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRALIPLADGFEEIEAMTVVDVLRRAGFEVVLAGLHGGPVESVRRVSVIPDATIDAARS
CCCCCCHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHEEEECCCCCCCCCCC
DQFDMVILPGGQPGAANLSADVRVIRLLNDFSKDNKLIGAICAATTVLSEAGLIRGKRVT
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
AYPDYRDRLPGAQYEDSAVVIDGKIITSQGPGTAMAFALAIVSRFAGKHTADEIAGKMLV
ECCCHHHCCCCCCCCCCEEEEECEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHCEEEE
QTDDRQHTIWDRYLFNTTVQSLVEALELKDSFTQGHAKRVSEYSLSIGAKLKLPPLEMRN
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHH
LYLGAMLHDIGKIATESDLLTKPDSLNLREETLMREHPIKGTLFIVGFDNMSNIVPTILH
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHH
HHERWDGSGYPARLKEEQIPLHARIVCLADAFAAMLFPRSFRPGMEREQAIQEILKQKGA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC
QFDPHLVDLFLECLTESPFEMNDFSFYF
CCCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]