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The map label for this gene is 118580531

Identifier: 118580531

GI number: 118580531

Start: 2274227

End: 2275330

Strand: Reverse

Name: 118580531

Synonym: Ppro_2115

Alternate gene names: NA

Gene position: 2275330-2274227 (Counterclockwise)

Preceding gene: 118580533

Following gene: 118580530

Centisome position: 56.77

GC content: 59.69

Gene sequence:

>1104_bases
ATGAAGGATCCCCGTGTACAACGGTTTGCGGAAATACTGGTGGATTATTCCACCAGAGTGGGGAAGGGAGATGTGGTGCT
GATCAACGCCGCCGGCCTGGAGGCGACCCCGCTGGTCAAGGAGATCTACCAACTCTGCCTGGAGCGCGGCGCCAGCTATG
TGGAATACGGCTTCAGCGTGCCGGAGATCGACCGCACCTTCTACAACCTGGCAAACCAGCAGCAGTTGGCGCACTTCCCC
CAGCACAAGCTGGACTTCTACAAGACCCTGACGGTCTACATCGGCATCGCAGCCGGCGAGAACTCCATGGTCATGGCCAA
TGCCCGCCAGGAGGCAATCGTGACCTACCAGAAGGTCACCAAACCGCTCATCGATCAGCGCGTCAAGCACACCCGCTGGG
TGGTGACCCGCTACCCGACCCATGCCGCGGCCCAGGAGGCCAGGATGAGTCTGGAGGAGTACGAGGAGTATCTCTTCTCC
GCCTGCTGCATCGACTGGGAGCAGGAGTCCCGCAAGCAGGAGAAGCTCAAGAAGCTGATGGACGGAACCTCGCGGGTGCG
CATCACTGCCCCGGATACGGATCTCAGCTTCAGCATCGGCGGGATGCCGGGGGTCAAATGCGATGGACGTTTCAATATGC
CCGACGGCGAGGTCTTCACGGCCCCGGTCAGGGAATCGGTTGAAGGTCACATAACCTACAACTGCCCCAGCATCTATCAG
GGCAAGGAGTTCAATGCCGTGCGCTTCGAGTTCTCCAGGGGAAGAATCGTGGCGGCATCCGCCGCTGGAGGAATGAGTGA
CGCCTTGAACAAAATCCTGGATACGGACGATGGCGCCCGCTACATCGGCGAGTTTGCCCTGGGGATCAACCCTGGTATCC
GTACCCCCATGCGCAACATCCTCTTTGACGAGAAGATCTTCGGCTCGATCCATCTCACCCCGGGGCAGGCCTACGACGAG
TGCGACAACGGCAACCGTTCCGCCGTGCACTGGGACCTGGTCAAGGTACTGACCGACGGCGGTGAAATCTGGTTTGATGA
TGTACTGATTCAGAAGAACGGGCTGTTCGTTCTTGACGCGCTGCTGGAACTGAACCCGGCCTGA

Upstream 100 bases:

>100_bases
AATCACAAATCGCGCGACAAAAAAAGAGCGGGCCGGAAGCGGAGGGTGGTGTTCCTTTGCTTCGCCGGTACGCCTCCCTG
TCGCGGAAAGGGTGCAATGT

Downstream 100 bases:

>100_bases
CAGGGGGGCACCATGATGGAACCGACCTTTCCCGAAGTCGAATTCGAACATGAAGACTTCGACTTTGACACCATGGACCA
GGAACTGCGGGTGAACGAAC

Product: peptidase M29, aminopeptidase II

Products: NA

Alternate protein names: Aminopeptidase II; AP-II [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKDPRVQRFAEILVDYSTRVGKGDVVLINAAGLEATPLVKEIYQLCLERGASYVEYGFSVPEIDRTFYNLANQQQLAHFP
QHKLDFYKTLTVYIGIAAGENSMVMANARQEAIVTYQKVTKPLIDQRVKHTRWVVTRYPTHAAAQEARMSLEEYEEYLFS
ACCIDWEQESRKQEKLKKLMDGTSRVRITAPDTDLSFSIGGMPGVKCDGRFNMPDGEVFTAPVRESVEGHITYNCPSIYQ
GKEFNAVRFEFSRGRIVAASAAGGMSDALNKILDTDDGARYIGEFALGINPGIRTPMRNILFDEKIFGSIHLTPGQAYDE
CDNGNRSAVHWDLVKVLTDGGEIWFDDVLIQKNGLFVLDALLELNPA

Sequences:

>Translated_367_residues
MKDPRVQRFAEILVDYSTRVGKGDVVLINAAGLEATPLVKEIYQLCLERGASYVEYGFSVPEIDRTFYNLANQQQLAHFP
QHKLDFYKTLTVYIGIAAGENSMVMANARQEAIVTYQKVTKPLIDQRVKHTRWVVTRYPTHAAAQEARMSLEEYEEYLFS
ACCIDWEQESRKQEKLKKLMDGTSRVRITAPDTDLSFSIGGMPGVKCDGRFNMPDGEVFTAPVRESVEGHITYNCPSIYQ
GKEFNAVRFEFSRGRIVAASAAGGMSDALNKILDTDDGARYIGEFALGINPGIRTPMRNILFDEKIFGSIHLTPGQAYDE
CDNGNRSAVHWDLVKVLTDGGEIWFDDVLIQKNGLFVLDALLELNPA
>Mature_367_residues
MKDPRVQRFAEILVDYSTRVGKGDVVLINAAGLEATPLVKEIYQLCLERGASYVEYGFSVPEIDRTFYNLANQQQLAHFP
QHKLDFYKTLTVYIGIAAGENSMVMANARQEAIVTYQKVTKPLIDQRVKHTRWVVTRYPTHAAAQEARMSLEEYEEYLFS
ACCIDWEQESRKQEKLKKLMDGTSRVRITAPDTDLSFSIGGMPGVKCDGRFNMPDGEVFTAPVRESVEGHITYNCPSIYQ
GKEFNAVRFEFSRGRIVAASAAGGMSDALNKILDTDDGARYIGEFALGINPGIRTPMRNILFDEKIFGSIHLTPGQAYDE
CDNGNRSAVHWDLVKVLTDGGEIWFDDVLIQKNGLFVLDALLELNPA

Specific function: Broad specificity metal-dependent exopeptidase, releasing all N-terminal amino acids [H]

COG id: COG2309

COG function: function code E; Leucyl aminopeptidase (aminopeptidase T)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M29 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000787 [H]

Pfam domain/function: PF02073 Peptidase_M29 [H]

EC number: NA

Molecular weight: Translated: 41188; Mature: 41188

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDPRVQRFAEILVDYSTRVGKGDVVLINAAGLEATPLVKEIYQLCLERGASYVEYGFSV
CCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEECCCCCC
PEIDRTFYNLANQQQLAHFPQHKLDFYKTLTVYIGIAAGENSMVMANARQEAIVTYQKVT
CHHHHHHHHHCCHHHHHHCCHHHHHHHEEEEEEEEEEECCCCEEEECCCHHHHHHHHHHH
KPLIDQRVKHTRWVVTRYPTHAAAQEARMSLEEYEEYLFSACCIDWEQESRKQEKLKKLM
HHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DGTSRVRITAPDTDLSFSIGGMPGVKCDGRFNMPDGEVFTAPVRESVEGHITYNCPSIYQ
CCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCEEECCHHCCCCCEEEECCCCCCC
GKEFNAVRFEFSRGRIVAASAAGGMSDALNKILDTDDGARYIGEFALGINPGIRTPMRNI
CCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
LFDEKIFGSIHLTPGQAYDECDNGNRSAVHWDLVKVLTDGGEIWFDDVLIQKNGLFVLDA
HHCHHHCCEEEECCCCCHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEH
LLELNPA
HHHCCCC
>Mature Secondary Structure
MKDPRVQRFAEILVDYSTRVGKGDVVLINAAGLEATPLVKEIYQLCLERGASYVEYGFSV
CCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEECCCCCC
PEIDRTFYNLANQQQLAHFPQHKLDFYKTLTVYIGIAAGENSMVMANARQEAIVTYQKVT
CHHHHHHHHHCCHHHHHHCCHHHHHHHEEEEEEEEEEECCCCEEEECCCHHHHHHHHHHH
KPLIDQRVKHTRWVVTRYPTHAAAQEARMSLEEYEEYLFSACCIDWEQESRKQEKLKKLM
HHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DGTSRVRITAPDTDLSFSIGGMPGVKCDGRFNMPDGEVFTAPVRESVEGHITYNCPSIYQ
CCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCEEECCHHCCCCCEEEECCCCCCC
GKEFNAVRFEFSRGRIVAASAAGGMSDALNKILDTDDGARYIGEFALGINPGIRTPMRNI
CCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHH
LFDEKIFGSIHLTPGQAYDECDNGNRSAVHWDLVKVLTDGGEIWFDDVLIQKNGLFVLDA
HHCHHHCCEEEECCCCCHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEH
LLELNPA
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9362117; 938681 [H]