| Definition | Pelobacter propionicus DSM 2379 chromosome, complete genome. |
|---|---|
| Accession | NC_008609 |
| Length | 4,008,000 |
Click here to switch to the map view.
The map label for this gene is dxr
Identifier: 118580466
GI number: 118580466
Start: 2198734
End: 2199894
Strand: Direct
Name: dxr
Synonym: Ppro_2050
Alternate gene names: 118580466
Gene position: 2198734-2199894 (Clockwise)
Preceding gene: 118580465
Following gene: 118580467
Centisome position: 54.86
GC content: 62.96
Gene sequence:
>1161_bases ATGAAACAGCTTTCAATACTTGGTTCCACCGGTTCCATCGGCGTCAGCACCCTGGAGATCGTTGCCGCCCACCCGGACCG GTTCCGGGTCAGCGCCCTGACCGCCGGAAAAAACCTGGAACTTTTGGCCCGCCAGATCAGACAGTTCTCTCCCCGCATCG CCGCCGTCGCAGCCAAGGAGGATGTTCCCCGCCTGGCCCAGCTCTGCGACGGCCTGGAGGTGAAGATCGTCGGAGGGGTG GAAGGGCTGATCGAGGCCGCAACAGCCGATGAAACGGACATGGTGGTGGCGGCCATTGTTGGCGCGGCCGGACTGGTTCC CACGGCAGCCGCCATCCGCGCCGGCAAGGATATCGCCCTGGCCAACAAGGAGACCCTGGTCACCGCCGGGCACCTGTTCA TGGAGATGGTCAGCAGCCACGGCGTCAAGCTCTACCCGGTGGACAGCGAGCACAGCGCCATCTTCCAGTCCCTGGAGGGG CATCGCAGCGATGACATCAGCAAGATCATCCTCACCGCCTCGGGCGGACCGTTTTTAAACACATCCCTGGAGCAGCTGGC CGGCGTCACGGTGGGCGATGCCCTCAACCATCCCAACTGGAGCATGGGGAGAAAGATCACCATCGACTCGGCAACCATGA TGAACAAGGGCCTGGAGGTCATCGAGGCCCGCTGGCTCTTCGACGCGCCGATGGAGAAAATCCATATCAACATCCATCCC CAAAGCATCATCCACTCCATGGTGGAGTACATCGACGGCTGCGTCATCGCCCAGCTGGGCATGCCGGACATGAAAGCGCC CATCGCCTACGCCCTCTCCTACCCCGAGCGGGTCGCCACCGGCATCAAGCCGCTGGACCTGACCACCCTCACGGGACTCA CCTTCTTCAAACCGGACCTGGAGAAATTCCGCTGCCTGGGGCTGGCCTACCGCGCCATGGCCGACGGAGAGAGCATGCCG GCGGTCATGAACGCGGCCAACGAGATCGCCGTGGATGCCTTCCTGGAGGGGCGCATCGCTTTCCTGCAGATCGCCCGGGT GATCGAGGAGACCATGGACAGCCACATTCCTCACGATCTGAAGTCCATAGCAGAGGTGCTTCAGGCCGATCAGTGGGGCC GCGACACGGCCCGTGACATCTGCAGGAGGCTCTCGAACTGA
Upstream 100 bases:
>100_bases TTCCCCGGCCACGGCGGAATCCTGGACCGCCTGGACAGCATCATCTTCGCCGCGCCTGCCACCTACTACTACGCAACCTA CTTTTTCAAGGGATAGTCTT
Downstream 100 bases:
>100_bases CATGACGGTCATCTATGCCATAATCGCACTCGGTGTCCTAATTTTCGTCCACGAGTTGGGACATTTCATCTTCGCCAAGC TGTTCAACGTCAAGGTGGAG
Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Products: NA
Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase
Number of amino acids: Translated: 386; Mature: 386
Protein sequence:
>386_residues MKQLSILGSTGSIGVSTLEIVAAHPDRFRVSALTAGKNLELLARQIRQFSPRIAAVAAKEDVPRLAQLCDGLEVKIVGGV EGLIEAATADETDMVVAAIVGAAGLVPTAAAIRAGKDIALANKETLVTAGHLFMEMVSSHGVKLYPVDSEHSAIFQSLEG HRSDDISKIILTASGGPFLNTSLEQLAGVTVGDALNHPNWSMGRKITIDSATMMNKGLEVIEARWLFDAPMEKIHINIHP QSIIHSMVEYIDGCVIAQLGMPDMKAPIAYALSYPERVATGIKPLDLTTLTGLTFFKPDLEKFRCLGLAYRAMADGESMP AVMNAANEIAVDAFLEGRIAFLQIARVIEETMDSHIPHDLKSIAEVLQADQWGRDTARDICRRLSN
Sequences:
>Translated_386_residues MKQLSILGSTGSIGVSTLEIVAAHPDRFRVSALTAGKNLELLARQIRQFSPRIAAVAAKEDVPRLAQLCDGLEVKIVGGV EGLIEAATADETDMVVAAIVGAAGLVPTAAAIRAGKDIALANKETLVTAGHLFMEMVSSHGVKLYPVDSEHSAIFQSLEG HRSDDISKIILTASGGPFLNTSLEQLAGVTVGDALNHPNWSMGRKITIDSATMMNKGLEVIEARWLFDAPMEKIHINIHP QSIIHSMVEYIDGCVIAQLGMPDMKAPIAYALSYPERVATGIKPLDLTTLTGLTFFKPDLEKFRCLGLAYRAMADGESMP AVMNAANEIAVDAFLEGRIAFLQIARVIEETMDSHIPHDLKSIAEVLQADQWGRDTARDICRRLSN >Mature_386_residues MKQLSILGSTGSIGVSTLEIVAAHPDRFRVSALTAGKNLELLARQIRQFSPRIAAVAAKEDVPRLAQLCDGLEVKIVGGV EGLIEAATADETDMVVAAIVGAAGLVPTAAAIRAGKDIALANKETLVTAGHLFMEMVSSHGVKLYPVDSEHSAIFQSLEG HRSDDISKIILTASGGPFLNTSLEQLAGVTVGDALNHPNWSMGRKITIDSATMMNKGLEVIEARWLFDAPMEKIHINIHP QSIIHSMVEYIDGCVIAQLGMPDMKAPIAYALSYPERVATGIKPLDLTTLTGLTFFKPDLEKFRCLGLAYRAMADGESMP AVMNAANEIAVDAFLEGRIAFLQIARVIEETMDSHIPHDLKSIAEVLQADQWGRDTARDICRRLSN
Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COG id: COG0743
COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DXR family
Homologues:
Organism=Escherichia coli, GI1786369, Length=401, Percent_Identity=49.3765586034913, Blast_Score=360, Evalue=1e-101,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DXR_PELPD (A1AQN8)
Other databases:
- EMBL: CP000482 - RefSeq: YP_901716.1 - ProteinModelPortal: A1AQN8 - SMR: A1AQN8 - STRING: A1AQN8 - GeneID: 4573893 - GenomeReviews: CP000482_GR - KEGG: ppd:Ppro_2050 - eggNOG: COG0743 - HOGENOM: HBG430762 - OMA: IHSMVEY - PhylomeDB: A1AQN8 - ProtClustDB: PRK05447 - HAMAP: MF_00183 - InterPro: IPR003821 - InterPro: IPR013644 - InterPro: IPR013512 - InterPro: IPR016040 - Gene3D: G3DSA:3.40.50.720 - PIRSF: PIRSF006205 - TIGRFAMs: TIGR00243
Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom
EC number: =1.1.1.267
Molecular weight: Translated: 41574; Mature: 41574
Theoretical pI: Translated: 5.41; Mature: 5.41
Prosite motif: NA
Important sites: BINDING 123-123 BINDING 150-150 BINDING 174-174 BINDING 197-197 BINDING 219-219
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKQLSILGSTGSIGVSTLEIVAAHPDRFRVSALTAGKNLELLARQIRQFSPRIAAVAAKE CCCEEEECCCCCCCHHEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCHHEEHHHHC DVPRLAQLCDGLEVKIVGGVEGLIEAATADETDMVVAAIVGAAGLVPTAAAIRAGKDIAL CHHHHHHHHCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEE ANKETLVTAGHLFMEMVSSHGVKLYPVDSEHSAIFQSLEGHRSDDISKIILTASGGPFLN CCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCC TSLEQLAGVTVGDALNHPNWSMGRKITIDSATMMNKGLEVIEARWLFDAPMEKIHINIHP CCHHHHCCCCHHHCCCCCCCCCCCEEEECHHHHHHCCHHHHHHHHHHCCCCEEEEEEECH QSIIHSMVEYIDGCVIAQLGMPDMKAPIAYALSYPERVATGIKPLDLTTLTGLTFFKPDL HHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHCCHHHHHCCCCCCCHHHHCCCHHCCCCH EKFRCLGLAYRAMADGESMPAVMNAANEIAVDAFLEGRIAFLQIARVIEETMDSHIPHDL HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH KSIAEVLQADQWGRDTARDICRRLSN HHHHHHHHHCCCCCHHHHHHHHHHCC >Mature Secondary Structure MKQLSILGSTGSIGVSTLEIVAAHPDRFRVSALTAGKNLELLARQIRQFSPRIAAVAAKE CCCEEEECCCCCCCHHEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCHHEEHHHHC DVPRLAQLCDGLEVKIVGGVEGLIEAATADETDMVVAAIVGAAGLVPTAAAIRAGKDIAL CHHHHHHHHCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEE ANKETLVTAGHLFMEMVSSHGVKLYPVDSEHSAIFQSLEGHRSDDISKIILTASGGPFLN CCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCC TSLEQLAGVTVGDALNHPNWSMGRKITIDSATMMNKGLEVIEARWLFDAPMEKIHINIHP CCHHHHCCCCHHHCCCCCCCCCCCEEEECHHHHHHCCHHHHHHHHHHCCCCEEEEEEECH QSIIHSMVEYIDGCVIAQLGMPDMKAPIAYALSYPERVATGIKPLDLTTLTGLTFFKPDL HHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHCCHHHHHCCCCCCCHHHHCCCHHCCCCH EKFRCLGLAYRAMADGESMPAVMNAANEIAVDAFLEGRIAFLQIARVIEETMDSHIPHDL HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH KSIAEVLQADQWGRDTARDICRRLSN HHHHHHHHHCCCCCHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA