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The map label for this gene is yaeL [C]

Identifier: 118580467

GI number: 118580467

Start: 2199896

End: 2201014

Strand: Direct

Name: yaeL [C]

Synonym: Ppro_2051

Alternate gene names: 118580467

Gene position: 2199896-2201014 (Clockwise)

Preceding gene: 118580466

Following gene: 118580468

Centisome position: 54.89

GC content: 61.66

Gene sequence:

>1119_bases
ATGACGGTCATCTATGCCATAATCGCACTCGGTGTCCTAATTTTCGTCCACGAGTTGGGACATTTCATCTTCGCCAAGCT
GTTCAACGTCAAGGTGGAGAAGTTTTCTCTTGGCTTCGGCCCCAAGCTGTTCGGCAGACAGATCGGCGAGACAGAGTATC
TGCTCTCGGCGTTCCCCCTGGGCGGCTACGTCAAGATGTTCGGCGAAGGGGGCTTCATCGAGGGGGGGGAGACCCACCAC
CAGCAGGACCCGGAAGAGTCGCCCGCGCAACGGGAATATACCGACGAGGAGAAGCGGCGTTCCTTTGCCCATAAACCGCC
CCTGGCACGCATCGCCATCGTCTTGGCCGGCCCGATCTTCAACCTGCTCTTCGCCTGGCTGGCGTTCATGCTGCTCTGCA
CGCTGGGGGTTCCCACCATCACCACCAGGATCGGCGAGGTGCTCAAGGACAAGCCGGCGGCCAGGGCCGGCATCATGAAG
GACGACCTGATCACCGCCGTAGATGGGCAGGCGGTTTACCGCTGGGAGGAGTTCGCCTCCAGCATCGCGGAGAGCAAGGG
CAAACCGATCAACCTGTCGGTGAAGCGCAAGGACAAGGAGCTGAGCTTCACCATCACCCCGGCGCCACGGGTGGCCAAGA
ACGTCTTCGGCGAGAATGTCAACGGCTATGCCATCGGCGTGGCGTCGGCGGGCGAGATCGTCACCGAGTACTACGACCCG
CTTCAGGCGGTGGTCAAGGGAACCAAGCAGACCTTTGTGGTCATCGACCTGACCATCACCTCGCTGATCAAGCTTGCCCA
GCGCATCGTGCCGCTGGATACGGTGGGAGGGCCGATCATGATCGCCAAGATGGCCGGCGAGCAGGCCTCGGCCGGCGGCG
CCAGCTTCCTGGCTTTCATGGCCCTGCTCTCCATCAACCTGGGCATTCTCAACCTGCTGCCGGTTCCGGTCCTGGACGGC
GGCCACCTGATCTTCTACATCTGGGAACTGGTCTTCCGCAGGCCGGTCAGGCAGCAGGTTCGGGAATACGCCCAGCAGAT
CGGCATGGCGCTCCTGCTCGGCCTGATGCTCTTGGCCTTCTACAACGACATCGTCCGTTATTTCGTCGGCCAGGGGTAA

Upstream 100 bases:

>100_bases
CACATTCCTCACGATCTGAAGTCCATAGCAGAGGTGCTTCAGGCCGATCAGTGGGGCCGCGACACGGCCCGTGACATCTG
CAGGAGGCTCTCGAACTGAC

Downstream 100 bases:

>100_bases
GCACTACGCACCGACAATCGAAAGCGCCGCGTCGCAGCAGGCCTAAAGCCGCCACGGGACGCGGCGTTTGGTTGTACGCT
CTGTTGTGCCTCTTTCCCCT

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTVIYAIIALGVLIFVHELGHFIFAKLFNVKVEKFSLGFGPKLFGRQIGETEYLLSAFPLGGYVKMFGEGGFIEGGETHH
QQDPEESPAQREYTDEEKRRSFAHKPPLARIAIVLAGPIFNLLFAWLAFMLLCTLGVPTITTRIGEVLKDKPAARAGIMK
DDLITAVDGQAVYRWEEFASSIAESKGKPINLSVKRKDKELSFTITPAPRVAKNVFGENVNGYAIGVASAGEIVTEYYDP
LQAVVKGTKQTFVVIDLTITSLIKLAQRIVPLDTVGGPIMIAKMAGEQASAGGASFLAFMALLSINLGILNLLPVPVLDG
GHLIFYIWELVFRRPVRQQVREYAQQIGMALLLGLMLLAFYNDIVRYFVGQG

Sequences:

>Translated_372_residues
MTVIYAIIALGVLIFVHELGHFIFAKLFNVKVEKFSLGFGPKLFGRQIGETEYLLSAFPLGGYVKMFGEGGFIEGGETHH
QQDPEESPAQREYTDEEKRRSFAHKPPLARIAIVLAGPIFNLLFAWLAFMLLCTLGVPTITTRIGEVLKDKPAARAGIMK
DDLITAVDGQAVYRWEEFASSIAESKGKPINLSVKRKDKELSFTITPAPRVAKNVFGENVNGYAIGVASAGEIVTEYYDP
LQAVVKGTKQTFVVIDLTITSLIKLAQRIVPLDTVGGPIMIAKMAGEQASAGGASFLAFMALLSINLGILNLLPVPVLDG
GHLIFYIWELVFRRPVRQQVREYAQQIGMALLLGLMLLAFYNDIVRYFVGQG
>Mature_371_residues
TVIYAIIALGVLIFVHELGHFIFAKLFNVKVEKFSLGFGPKLFGRQIGETEYLLSAFPLGGYVKMFGEGGFIEGGETHHQ
QDPEESPAQREYTDEEKRRSFAHKPPLARIAIVLAGPIFNLLFAWLAFMLLCTLGVPTITTRIGEVLKDKPAARAGIMKD
DLITAVDGQAVYRWEEFASSIAESKGKPINLSVKRKDKELSFTITPAPRVAKNVFGENVNGYAIGVASAGEIVTEYYDPL
QAVVKGTKQTFVVIDLTITSLIKLAQRIVPLDTVGGPIMIAKMAGEQASAGGASFLAFMALLSINLGILNLLPVPVLDGG
HLIFYIWELVFRRPVRQQVREYAQQIGMALLLGLMLLAFYNDIVRYFVGQG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=238, Percent_Identity=37.3949579831933, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 40871; Mature: 40739

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVIYAIIALGVLIFVHELGHFIFAKLFNVKVEKFSLGFGPKLFGRQIGETEYLLSAFPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCCHHHHHHHCCC
GGYVKMFGEGGFIEGGETHHQQDPEESPAQREYTDEEKRRSFAHKPPLARIAIVLAGPIF
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
NLLFAWLAFMLLCTLGVPTITTRIGEVLKDKPAARAGIMKDDLITAVDGQAVYRWEEFAS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHEECCCHHHHHHHHHHH
SIAESKGKPINLSVKRKDKELSFTITPAPRVAKNVFGENVNGYAIGVASAGEIVTEYYDP
HHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
LQAVVKGTKQTFVVIDLTITSLIKLAQRIVPLDTVGGPIMIAKMAGEQASAGGASFLAFM
HHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHH
ALLSINLGILNLLPVPVLDGGHLIFYIWELVFRRPVRQQVREYAQQIGMALLLGLMLLAF
HHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNDIVRYFVGQG
HHHHHHHHHCCC
>Mature Secondary Structure 
TVIYAIIALGVLIFVHELGHFIFAKLFNVKVEKFSLGFGPKLFGRQIGETEYLLSAFPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCCHHHHHHHCCC
GGYVKMFGEGGFIEGGETHHQQDPEESPAQREYTDEEKRRSFAHKPPLARIAIVLAGPIF
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
NLLFAWLAFMLLCTLGVPTITTRIGEVLKDKPAARAGIMKDDLITAVDGQAVYRWEEFAS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHEECCCHHHHHHHHHHH
SIAESKGKPINLSVKRKDKELSFTITPAPRVAKNVFGENVNGYAIGVASAGEIVTEYYDP
HHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
LQAVVKGTKQTFVVIDLTITSLIKLAQRIVPLDTVGGPIMIAKMAGEQASAGGASFLAFM
HHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHH
ALLSINLGILNLLPVPVLDGGHLIFYIWELVFRRPVRQQVREYAQQIGMALLLGLMLLAF
HHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNDIVRYFVGQG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]