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The map label for this gene is nifU [H]

Identifier: 118580432

GI number: 118580432

Start: 2165665

End: 2166537

Strand: Reverse

Name: nifU [H]

Synonym: Ppro_2016

Alternate gene names: 118580432

Gene position: 2166537-2165665 (Counterclockwise)

Preceding gene: 118580433

Following gene: 118580431

Centisome position: 54.06

GC content: 58.88

Gene sequence:

>873_bases
ATGTGGGATTACACACCGATCGTTAAAGATCATTTTCTGAACCCGCGCAACGTTGGGGACATACCCGACGCCGACGCCAT
AGGTGAAGTGGGCAGTCTGGCATGCGGCGACGCGCTCAAGCTGTATCTCAAGCTGGACGAACACAAGGAACGGATCGTGG
ACGCCAGGTTCCAGACTTTTGGCTGCGCCAGCGCCATCGCATCCTCGTCTGCCCTGACCGAGATGCTCAAGGGCAAGACC
CTGGACGAGGCCCTGGCTATCAGTAATCAGGATATCGCCGAGTTTCTGGGCGGGTTGCCGGAAGAGAAGATGCACTGTTC
GGTCATGGGGCAGGAGGCTCTGGAGGTTGCCATAGCAAAGTACCGCGGCGAGCCGATCCCCGCCCATGACAGCGAACATG
ACCATGGCCATGCCTACCCCGATTATGAGGGGGAGCTGGTCTGCAAGTGTTTCGGCATAACCGATGCCTATCTCAAAAAA
GTCATTGAAACAAACAAGCTGACCACTGTTGAGCAGGTGACTAATTTTACCAAGGCTGGTGGAGCCTGCGGCGGCTGCAT
TTCCAGTATCAAGGAGCTGATTGCCCAAGTGCTGGGCGGGGCAGAAGCCCAACCGCGCAAGCGCCCCGAGAAGCTCTCCA
ACATGAAGCGGATGCAGATGATCCAGGAGGTGCTGGAGCGCGACATTCGGCCGCTGCTGTGGGCCGATGGCGGCGATCTG
GAGCTGATCGATATCGACGGACCAAAGGTTCAGGTGGCCTTCCGCAAGGCGTGTGCCGGCTGCGCATCTTCCGGCAACAC
GGCGCGCATGGTCGAGCACAAGCTGCGCGACCTGGTGGCCGAGGATATCGTTGTCGAGGAGGTGTCCGCATGA

Upstream 100 bases:

>100_bases
TGGAGAGGCGTCGTCGGATGCCCGTCTGGCGGAAGTCATGACCGCTGGCCGCGCCTTTATAGGTAGTTAATTTTATTCGA
GTTGTTCGGAGGAAACACCG

Downstream 100 bases:

>100_bases
GGGAGATCTATCTGGACAACAATGCCACCACCAAGGTTGACGAAGCGGTCTTCGAGGAGATGCGCCCCTATTTCTGCGAA
CTGTACGGCAACCCCAGTTC

Product: Fe-S cluster assembly protein NifU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MWDYTPIVKDHFLNPRNVGDIPDADAIGEVGSLACGDALKLYLKLDEHKERIVDARFQTFGCASAIASSSALTEMLKGKT
LDEALAISNQDIAEFLGGLPEEKMHCSVMGQEALEVAIAKYRGEPIPAHDSEHDHGHAYPDYEGELVCKCFGITDAYLKK
VIETNKLTTVEQVTNFTKAGGACGGCISSIKELIAQVLGGAEAQPRKRPEKLSNMKRMQMIQEVLERDIRPLLWADGGDL
ELIDIDGPKVQVAFRKACAGCASSGNTARMVEHKLRDLVAEDIVVEEVSA

Sequences:

>Translated_290_residues
MWDYTPIVKDHFLNPRNVGDIPDADAIGEVGSLACGDALKLYLKLDEHKERIVDARFQTFGCASAIASSSALTEMLKGKT
LDEALAISNQDIAEFLGGLPEEKMHCSVMGQEALEVAIAKYRGEPIPAHDSEHDHGHAYPDYEGELVCKCFGITDAYLKK
VIETNKLTTVEQVTNFTKAGGACGGCISSIKELIAQVLGGAEAQPRKRPEKLSNMKRMQMIQEVLERDIRPLLWADGGDL
ELIDIDGPKVQVAFRKACAGCASSGNTARMVEHKLRDLVAEDIVVEEVSA
>Mature_290_residues
MWDYTPIVKDHFLNPRNVGDIPDADAIGEVGSLACGDALKLYLKLDEHKERIVDARFQTFGCASAIASSSALTEMLKGKT
LDEALAISNQDIAEFLGGLPEEKMHCSVMGQEALEVAIAKYRGEPIPAHDSEHDHGHAYPDYEGELVCKCFGITDAYLKK
VIETNKLTTVEQVTNFTKAGGACGGCISSIKELIAQVLGGAEAQPRKRPEKLSNMKRMQMIQEVLERDIRPLLWADGGDL
ELIDIDGPKVQVAFRKACAGCASSGNTARMVEHKLRDLVAEDIVVEEVSA

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI24307953, Length=123, Percent_Identity=52.0325203252033, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI56699456, Length=122, Percent_Identity=52.4590163934426, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1788878, Length=124, Percent_Identity=51.6129032258064, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17543474, Length=122, Percent_Identity=46.7213114754098, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324800, Length=128, Percent_Identity=44.53125, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6325122, Length=125, Percent_Identity=44, Blast_Score=108, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21355597, Length=122, Percent_Identity=50, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR016217
- InterPro:   IPR010238
- InterPro:   IPR001075
- InterPro:   IPR002871
- ProDom:   PD002830 [H]

Pfam domain/function: PF04324 Fer2_BFD; PF01106 NifU; PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 31586; Mature: 31586

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWDYTPIVKDHFLNPRNVGDIPDADAIGEVGSLACGDALKLYLKLDEHKERIVDARFQTF
CCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCASAIASSSALTEMLKGKTLDEALAISNQDIAEFLGGLPEEKMHCSVMGQEALEVAIAK
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
YRGEPIPAHDSEHDHGHAYPDYEGELVCKCFGITDAYLKKVIETNKLTTVEQVTNFTKAG
HCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCC
GACGGCISSIKELIAQVLGGAEAQPRKRPEKLSNMKRMQMIQEVLERDIRPLLWADGGDL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCE
ELIDIDGPKVQVAFRKACAGCASSGNTARMVEHKLRDLVAEDIVVEEVSA
EEEECCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWDYTPIVKDHFLNPRNVGDIPDADAIGEVGSLACGDALKLYLKLDEHKERIVDARFQTF
CCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GCASAIASSSALTEMLKGKTLDEALAISNQDIAEFLGGLPEEKMHCSVMGQEALEVAIAK
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
YRGEPIPAHDSEHDHGHAYPDYEGELVCKCFGITDAYLKKVIETNKLTTVEQVTNFTKAG
HCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCC
GACGGCISSIKELIAQVLGGAEAQPRKRPEKLSNMKRMQMIQEVLERDIRPLLWADGGDL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCE
ELIDIDGPKVQVAFRKACAGCASSGNTARMVEHKLRDLVAEDIVVEEVSA
EEEECCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7496536 [H]