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The map label for this gene is pgk

Identifier: 118580115

GI number: 118580115

Start: 1820905

End: 1822104

Strand: Direct

Name: pgk

Synonym: Ppro_1694

Alternate gene names: 118580115

Gene position: 1820905-1822104 (Clockwise)

Preceding gene: 118580114

Following gene: 118580116

Centisome position: 45.43

GC content: 61.08

Gene sequence:

>1200_bases
ATGCCGATTCGCTACATCGACCAACTTGCCGACTTGAAGGATAAGAAGGTGTTTATTCGCGTTGACTTCAACGTTCCCCA
GGATTCCAAGGGCAACATCACCGAGGATACCCGCATCACCGGAGCCCTGCCGACCATCAGGTACGCCATCGAGCAGGGGG
CCAGGGTGATCCTGGCCTCCCATCTGGGGCGCCCCAAGGGGGAGAAGAACGAGAAATACAGCATGGTTCCGGCCGCCAAG
CGTCTGTCGGAATTGTTGGGGAGGAAGGTCAAGCAGGCCTCGGACTGCTTCGGCGAAGAGGTGACTCGAGAGATCGATGC
CATGAAATCGGGCGAGGTGCTGATGCTGGAGAATGTGCGCTTCTACCCCGGCGAGGAGAAGAACGACCCCAAGTTCGCCC
AGCAGTTGGCCAATGGCTGCCAGGTCTACGTCAATGACGCCTTTGCCGTGTCCCATCGCGCCCATGCCTCGGTTGAGGCG
ATCACCAGGGTGATTCCCACCGTGGTGGCCGGTTTTCTGATGAGAAACGAGATGACCTTCTTCGACAAGGCCATGCAGAA
CCCGGTGCGTCCCCTGGTGGCCATTCTCGGCGGCGCCAAGGTCTCCGGCAAGCTGGAGGTGCTGGAAAAACTGATGAACA
AGGTGGACAAGGTGGTGATCGGCGGCGGTATGGCATTCACCTTCCTCAAGTCCATGGGATACTCGGTGGGCGCCTCCAAG
GTGGAGGACGAACTGCTCCCCACCGCCAAGAAGATCATGGACAAGGCCAGGAAGAAGGGAATCATGTTCTACCTACCGGT
GGACTGCGTGGTGGCCAACGCCTTCGAGGCGAGCGCCACCAACTTCATCACCACCGTCCAGGAGATCCCCGAGGGGTGGC
TGGCGCTGGATATCGGACCGGCGTCGGCAACGCTCTTCACCGAGACCCTGCGTGACGCCAAGACCGTCATCTGGAACGGC
CCCATGGGAGTCTTCGAGATGGACGCCTTTGCCCGCGGCACCTTTGCCGTGGCCGAGGCGGTGGCAAGCGCCTTCGCCAC
CACCATCATCGGCGGCGGCGACACCGATTCCGCCGTACGCAAGGCGGGGGTGGAGAGCAAGGTCAGCTACATTTCCACCG
GCGGTGGCGCGTTCCTGGAGCTGCTGGAGGGCAAGGTTCTGCCCGGCGTGAAGGCGCTGGACATCAAGGTCAAGAAATAG

Upstream 100 bases:

>100_bases
GCATCGAAAAAGTAGTCTTTTGCCGCTGATATTCGAGGGGGAACTCGCGTTTCTCCCTCTTTTTTTGTGATACCCATTCC
ATGCCCCAAGGAGGAGCCCC

Downstream 100 bases:

>100_bases
GGGGGAGTCCATGCGCACGCCGCTGATCGCAGGAAACTGGAAACTGCACAAGACCATTGCCGAGTCGTTGGCCATGGTGG
ATGAACTGAAACCGCTGGTG

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MPIRYIDQLADLKDKKVFIRVDFNVPQDSKGNITEDTRITGALPTIRYAIEQGARVILASHLGRPKGEKNEKYSMVPAAK
RLSELLGRKVKQASDCFGEEVTREIDAMKSGEVLMLENVRFYPGEEKNDPKFAQQLANGCQVYVNDAFAVSHRAHASVEA
ITRVIPTVVAGFLMRNEMTFFDKAMQNPVRPLVAILGGAKVSGKLEVLEKLMNKVDKVVIGGGMAFTFLKSMGYSVGASK
VEDELLPTAKKIMDKARKKGIMFYLPVDCVVANAFEASATNFITTVQEIPEGWLALDIGPASATLFTETLRDAKTVIWNG
PMGVFEMDAFARGTFAVAEAVASAFATTIIGGGDTDSAVRKAGVESKVSYISTGGGAFLELLEGKVLPGVKALDIKVKK

Sequences:

>Translated_399_residues
MPIRYIDQLADLKDKKVFIRVDFNVPQDSKGNITEDTRITGALPTIRYAIEQGARVILASHLGRPKGEKNEKYSMVPAAK
RLSELLGRKVKQASDCFGEEVTREIDAMKSGEVLMLENVRFYPGEEKNDPKFAQQLANGCQVYVNDAFAVSHRAHASVEA
ITRVIPTVVAGFLMRNEMTFFDKAMQNPVRPLVAILGGAKVSGKLEVLEKLMNKVDKVVIGGGMAFTFLKSMGYSVGASK
VEDELLPTAKKIMDKARKKGIMFYLPVDCVVANAFEASATNFITTVQEIPEGWLALDIGPASATLFTETLRDAKTVIWNG
PMGVFEMDAFARGTFAVAEAVASAFATTIIGGGDTDSAVRKAGVESKVSYISTGGGAFLELLEGKVLPGVKALDIKVKK
>Mature_398_residues
PIRYIDQLADLKDKKVFIRVDFNVPQDSKGNITEDTRITGALPTIRYAIEQGARVILASHLGRPKGEKNEKYSMVPAAKR
LSELLGRKVKQASDCFGEEVTREIDAMKSGEVLMLENVRFYPGEEKNDPKFAQQLANGCQVYVNDAFAVSHRAHASVEAI
TRVIPTVVAGFLMRNEMTFFDKAMQNPVRPLVAILGGAKVSGKLEVLEKLMNKVDKVVIGGGMAFTFLKSMGYSVGASKV
EDELLPTAKKIMDKARKKGIMFYLPVDCVVANAFEASATNFITTVQEIPEGWLALDIGPASATLFTETLRDAKTVIWNGP
MGVFEMDAFARGTFAVAEAVASAFATTIIGGGDTDSAVRKAGVESKVSYISTGGGAFLELLEGKVLPGVKALDIKVKK

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI4505763, Length=410, Percent_Identity=45.3658536585366, Blast_Score=334, Evalue=1e-91,
Organism=Homo sapiens, GI31543397, Length=410, Percent_Identity=44.1463414634146, Blast_Score=330, Evalue=1e-90,
Organism=Escherichia coli, GI1789294, Length=391, Percent_Identity=43.7340153452685, Blast_Score=309, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17508823, Length=409, Percent_Identity=45.4767726161369, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6319857, Length=412, Percent_Identity=49.2718446601942, Blast_Score=368, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24581203, Length=405, Percent_Identity=43.2098765432099, Blast_Score=317, Evalue=8e-87,
Organism=Drosophila melanogaster, GI17136394, Length=404, Percent_Identity=44.5544554455446, Blast_Score=315, Evalue=2e-86,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_PELPD (A1APN7)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_901365.1
- ProteinModelPortal:   A1APN7
- SMR:   A1APN7
- STRING:   A1APN7
- GeneID:   4572429
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1694
- eggNOG:   COG0126
- HOGENOM:   HBG453500
- OMA:   NCAIILP
- PhylomeDB:   A1APN7
- ProtClustDB:   PRK00073
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 43270; Mature: 43139

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 38-38 BINDING 120-120 BINDING 153-153 BINDING 204-204 BINDING 326-326

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRYIDQLADLKDKKVFIRVDFNVPQDSKGNITEDTRITGALPTIRYAIEQGARVILAS
CCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCEEEHH
HLGRPKGEKNEKYSMVPAAKRLSELLGRKVKQASDCFGEEVTREIDAMKSGEVLMLENVR
HCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECEE
FYPGEEKNDPKFAQQLANGCQVYVNDAFAVSHRAHASVEAITRVIPTVVAGFLMRNEMTF
ECCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FDKAMQNPVRPLVAILGGAKVSGKLEVLEKLMNKVDKVVIGGGMAFTFLKSMGYSVGASK
HHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCCHH
VEDELLPTAKKIMDKARKKGIMFYLPVDCVVANAFEASATNFITTVQEIPEGWLALDIGP
HHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
ASATLFTETLRDAKTVIWNGPMGVFEMDAFARGTFAVAEAVASAFATTIIGGGDTDSAVR
CHHHHHHHHHHHCCEEEECCCCCCEEHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KAGVESKVSYISTGGGAFLELLEGKVLPGVKALDIKVKK
HHCCHHHHHHEECCCHHHHHHHCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
PIRYIDQLADLKDKKVFIRVDFNVPQDSKGNITEDTRITGALPTIRYAIEQGARVILAS
CCHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCEEEHH
HLGRPKGEKNEKYSMVPAAKRLSELLGRKVKQASDCFGEEVTREIDAMKSGEVLMLENVR
HCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECEE
FYPGEEKNDPKFAQQLANGCQVYVNDAFAVSHRAHASVEAITRVIPTVVAGFLMRNEMTF
ECCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
FDKAMQNPVRPLVAILGGAKVSGKLEVLEKLMNKVDKVVIGGGMAFTFLKSMGYSVGASK
HHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCCHH
VEDELLPTAKKIMDKARKKGIMFYLPVDCVVANAFEASATNFITTVQEIPEGWLALDIGP
HHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
ASATLFTETLRDAKTVIWNGPMGVFEMDAFARGTFAVAEAVASAFATTIIGGGDTDSAVR
CHHHHHHHHHHHCCEEEECCCCCCEEHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KAGVESKVSYISTGGGAFLELLEGKVLPGVKALDIKVKK
HHCCHHHHHHEECCCHHHHHHHCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA