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The map label for this gene is btuR [C]

Identifier: 118580040

GI number: 118580040

Start: 1733309

End: 1733896

Strand: Direct

Name: btuR [C]

Synonym: Ppro_1617

Alternate gene names: 118580040

Gene position: 1733309-1733896 (Clockwise)

Preceding gene: 118580038

Following gene: 118580046

Centisome position: 43.25

GC content: 60.2

Gene sequence:

>588_bases
ATGCTGGAAAAGGGATACGTGCAGATCTACACGGGGAATGGAAAGGGGAAGACGACGGCGGCCATCGGACTGGCGGTACG
GGCGCTGGGCGCTGGGTTGCGGGTGCTCTTCCTGCAGTTCATGAAATCACGGGTCTACAGCGAACATGACATCATGCCGG
CCATATCCCCCAATCTGACCCTGGAAACCATGGGCAAACCGTACTTCGTGGTTGAGGAGGGGAGCGTTCCCCAGGAGGAG
ATCGATAAGTGGGGGGAGGGGGTGGTTGTCTTCCCTCCGGGAAAACCGCCCCGCGACTATGTGGAGATCGTGGCCAAGGG
GATGGAGAGGGCCAGGCAGGCGGTTAGCAGTGGCGAGTACGATCTGGTGGTTCTTGACGAAATCGTGGTGGCGCTGCATT
TCGGGCTCGTGAGCTGGGAGCAGGTGCGGGATGTCCTTGATTGCAAAAAAGATTCGGTGGAACTTGTGCTTACCGGCAGG
GGCGCCAGTCCCGAGCTGCTGGCGCGGGCCGATCTGGTTACGGAGATGCGGGAGACCAAGCATTATTACGCCAGCGGCGT
GGAGGCCAGGAAGGGGATCGAATGCTGA

Upstream 100 bases:

>100_bases
CGGCCTGGTACAAATCATGGCGGAAGTGCTATGCTCTCGGCTTGAGTGTATGAGGCACACGGGTGCAAGCTCGAATAGCG
AATCGGAAAGGGGGAGAACA

Downstream 100 bases:

>100_bases
GGAGTGTGCCGCCGGTATTGACACCAGATGTTCCGGCCAGCGCCAGATGAGGATGGGGCGTGCTGCCTGGAGCCACACGA
CATAACCTGGACAGCGGTGC

Product: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP

Products: triphosphate; adenosylcob(III)yrinic acid a,c-diamide; Adenosyl cobinamide

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MLEKGYVQIYTGNGKGKTTAAIGLAVRALGAGLRVLFLQFMKSRVYSEHDIMPAISPNLTLETMGKPYFVVEEGSVPQEE
IDKWGEGVVVFPPGKPPRDYVEIVAKGMERARQAVSSGEYDLVVLDEIVVALHFGLVSWEQVRDVLDCKKDSVELVLTGR
GASPELLARADLVTEMRETKHYYASGVEARKGIEC

Sequences:

>Translated_195_residues
MLEKGYVQIYTGNGKGKTTAAIGLAVRALGAGLRVLFLQFMKSRVYSEHDIMPAISPNLTLETMGKPYFVVEEGSVPQEE
IDKWGEGVVVFPPGKPPRDYVEIVAKGMERARQAVSSGEYDLVVLDEIVVALHFGLVSWEQVRDVLDCKKDSVELVLTGR
GASPELLARADLVTEMRETKHYYASGVEARKGIEC
>Mature_195_residues
MLEKGYVQIYTGNGKGKTTAAIGLAVRALGAGLRVLFLQFMKSRVYSEHDIMPAISPNLTLETMGKPYFVVEEGSVPQEE
IDKWGEGVVVFPPGKPPRDYVEIVAKGMERARQAVSSGEYDLVVLDEIVVALHFGLVSWEQVRDVLDCKKDSVELVLTGR
GASPELLARADLVTEMRETKHYYASGVEARKGIEC

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: 2.5.1.17

Molecular weight: Translated: 21476; Mature: 21476

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKGYVQIYTGNGKGKTTAAIGLAVRALGAGLRVLFLQFMKSRVYSEHDIMPAISPNLT
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCE
LETMGKPYFVVEEGSVPQEEIDKWGEGVVVFPPGKPPRDYVEIVAKGMERARQAVSSGEY
EEECCCEEEEEECCCCCHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DLVVLDEIVVALHFGLVSWEQVRDVLDCKKDSVELVLTGRGASPELLARADLVTEMRETK
CEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
HYYASGVEARKGIEC
HHHHCCCCCCCCCCC
>Mature Secondary Structure
MLEKGYVQIYTGNGKGKTTAAIGLAVRALGAGLRVLFLQFMKSRVYSEHDIMPAISPNLT
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCE
LETMGKPYFVVEEGSVPQEEIDKWGEGVVVFPPGKPPRDYVEIVAKGMERARQAVSSGEY
EEECCCEEEEEECCCCCHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DLVVLDEIVVALHFGLVSWEQVRDVLDCKKDSVELVLTGRGASPELLARADLVTEMRETK
CEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
HYYASGVEARKGIEC
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)yrinic acid a,c-diamide; cobinamide

Specific reaction: (1) ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide; (2) ATP + cobinamide = triphosphate + adenosylcobinamide

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840; 7883709 [H]