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The map label for this gene is trpG [H]

Identifier: 118580004

GI number: 118580004

Start: 1688686

End: 1689261

Strand: Reverse

Name: trpG [H]

Synonym: Ppro_1581

Alternate gene names: 118580004

Gene position: 1689261-1688686 (Counterclockwise)

Preceding gene: 118580005

Following gene: 118580003

Centisome position: 42.15

GC content: 62.67

Gene sequence:

>576_bases
ATGCTTTTGATGATCGACAACTACGACTCCTTCACCTTCAACATCGTCCAGTACTTCGGTCAACTGGGTGAAAATGTGCG
GGTGCACCGCAACGACAAAATCACCCTTGATGAGATTGAAACCATGCGCCCCCAGCGGCTGGTCATATCCCCCGGACCCT
GTTCCCCCGAAGAGGCCGGCATCTCCGTGGCAGCCATCAGGCACTTCGCCGGCAAGATCCCGATCCTGGGGGTCTGTCTG
GGGCACCAGGCCATCGGCGCCGCCTTTGGCGGCAACGTGGTACGCAGCGTGTCGCTGATGCACGGCAAGACCTCCCCCAT
CCACCACGATGGCAGGGAACTGTTCCAGGGCCTAGCCAATCCCTTCCAGGCCACCCGCTACCACTCCCTGGTGGTGGACC
GCCCCACCTTGCCGGACTGCCTGGAGGTGACCGCCTGGGTGGACAACGGCGAGATCATGGGACTGCGCCACCGGCAGCTG
CCCATCTGGGGGGTGCAGTTCCACCCCGAATCGATCCTCACCGAGGGGGGCATGGAGATGCTGGCCAACTTCCTGCGCAT
CAGCGCACATCGGTGA

Upstream 100 bases:

>100_bases
GTGGCAGACTCGGACCCGGCCGCGGAGTGGCAGGAGACTGTCAACAAGGCCATGGCCGCGCGACGGGCCATCGAGATCGC
CGAGGGAGGGCTGGAATAAA

Downstream 100 bases:

>100_bases
GAAGTGAAGCGTGAGGTCTCTTTCCCCCTCACTCCTTACCCTTCACCGATGTATGCCAATACCAGAACATATCGTTATTT
CGGGGGAGAAGGGCTGCATA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MLLMIDNYDSFTFNIVQYFGQLGENVRVHRNDKITLDEIETMRPQRLVISPGPCSPEEAGISVAAIRHFAGKIPILGVCL
GHQAIGAAFGGNVVRSVSLMHGKTSPIHHDGRELFQGLANPFQATRYHSLVVDRPTLPDCLEVTAWVDNGEIMGLRHRQL
PIWGVQFHPESILTEGGMEMLANFLRISAHR

Sequences:

>Translated_191_residues
MLLMIDNYDSFTFNIVQYFGQLGENVRVHRNDKITLDEIETMRPQRLVISPGPCSPEEAGISVAAIRHFAGKIPILGVCL
GHQAIGAAFGGNVVRSVSLMHGKTSPIHHDGRELFQGLANPFQATRYHSLVVDRPTLPDCLEVTAWVDNGEIMGLRHRQL
PIWGVQFHPESILTEGGMEMLANFLRISAHR
>Mature_191_residues
MLLMIDNYDSFTFNIVQYFGQLGENVRVHRNDKITLDEIETMRPQRLVISPGPCSPEEAGISVAAIRHFAGKIPILGVCL
GHQAIGAAFGGNVVRSVSLMHGKTSPIHHDGRELFQGLANPFQATRYHSLVVDRPTLPDCLEVTAWVDNGEIMGLRHRQL
PIWGVQFHPESILTEGGMEMLANFLRISAHR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=63.7837837837838, Blast_Score=262, Evalue=1e-71,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=42.7807486631016, Blast_Score=149, Evalue=8e-38,
Organism=Escherichia coli, GI1786215, Length=175, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=188, Percent_Identity=50, Blast_Score=198, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=33.175355450237, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281365319, Length=139, Percent_Identity=33.0935251798561, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21248; Mature: 21248

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTFNIVQYFGQLGENVRVHRNDKITLDEIETMRPQRLVISPGPCSPEEAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCEEHHHHHHCCCCEEEECCCCCCHHHHC
ISVAAIRHFAGKIPILGVCLGHQAIGAAFGGNVVRSVSLMHGKTSPIHHDGRELFQGLAN
CHHHHHHHHHCCCCEEEEECCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
PFQATRYHSLVVDRPTLPDCLEVTAWVDNGEIMGLRHRQLPIWGVQFHPESILTEGGMEM
HHHHHHHHEEEEECCCCCHHHEEEEEECCCEEEEEECCCCCEEEEEECCHHHHHCCCHHH
LANFLRISAHR
HHHHHHHHCCC
>Mature Secondary Structure
MLLMIDNYDSFTFNIVQYFGQLGENVRVHRNDKITLDEIETMRPQRLVISPGPCSPEEAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCEEHHHHHHCCCCEEEECCCCCCHHHHC
ISVAAIRHFAGKIPILGVCLGHQAIGAAFGGNVVRSVSLMHGKTSPIHHDGRELFQGLAN
CHHHHHHHHHCCCCEEEEECCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
PFQATRYHSLVVDRPTLPDCLEVTAWVDNGEIMGLRHRQLPIWGVQFHPESILTEGGMEM
HHHHHHHHEEEEECCCCCHHHEEEEEECCCEEEEEECCCCCEEEEEECCHHHHHCCCHHH
LANFLRISAHR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404959; 659439 [H]