Click here to switch to the map view.

The map label for this gene is acoR [H]

Identifier: 118579979

GI number: 118579979

Start: 1661163

End: 1663136

Strand: Direct

Name: acoR [H]

Synonym: Ppro_1556

Alternate gene names: 118579979

Gene position: 1661163-1663136 (Clockwise)

Preceding gene: 118579960

Following gene: 118579980

Centisome position: 41.45

GC content: 62.72

Gene sequence:

>1974_bases
GTGAACAAGTTTCCCCTCGTCAGCCTGGTCAAGATCAAGCGGGCGCGAAATTTTTTCTTCAATCAGGGCGCGGTTCCTCC
TGGTCTGGTGCCTGAGTTTATCGTCCGCTCCTGGCAGCGCTCGCTGATCAACGGTGTGCCCGTGGACGACGAGTCCCGTG
AAATCCCCCTGCTCACCGGCAGGGAGCTGACCTGTGCCAAGGAGGAGAGTCGGGACCTGCTGAACCATTCCCTGCCGGTG
ATGGAGAATCTCTACGAGCAGATCATTCACACCTCCAGCAAGGTGCTCCTGGCCGATGCTTCGGGTGTGGTGCTGCACTC
CTACGGCGATCCCGATTTCCTGGGGCGGACCCGCAAGGTGTCCCTGCTGCCCGGCGGCATCTGGTCGGAAGGGATCCGCG
GCACCAACGCCATCGGCACCTCGCTGGTGGAGCAGGAACCGGTTGTGGTGCACAGCGCCGAGCACTTCATCGCCAGCAAC
CATTTTCTCACCTGTTCCGCCTCCCCCATCTTCGATCCCTTTGGCAGGATCATGGGGGTCCTGGATGTGTCCGGTGATGG
CCGCGTGCATCAACCGCACACCATGGCGCTGGTGCGCATCTCGGTCCAGCAGATCGAGAACCAGATGTTTTCATGCGGAT
TCGAGCACGATCTGGTGCTGCACTTTCACGTTCGCCCCGAGTTCGTCGGCACCATGTACGAGGGGATCGCCGTGTTTTCC
CAGGATGGAAAGTTTCTGGCAGCCAACCGCAACGCGTTGCAGCATCTGGAGATGGATCGCTACCAGGCCGAATCCCACTG
CTTCTCTTCCCTGTTCAACTCACCCCTGGCGGCGATCTTCGACCAGCCGGGGCAGTTTCCGCGCCCGGTGCAGCAGCTGC
GCACCTGCACCGGCATCACCATTTACTGCCGCGGCAAGACCAGGTTGATCAACACCTCCAAGATCCCGCTGGTCATGGGG
AAACCGGTCAGCGCTTCCCCCGCGCCTCTGGGTGATGCCGAACGGAAGCCGCTCCTGGAGGAGTTGGAACTGGGCGATTT
GGGGATGCAGAAGCTCATCGCCCGGGCGCGCAAGGTTTTGGGGCACGACATACCGGTCCTGCTGGAAGGGGAATCGGGCA
CCGGCAAGGAGCTGTTCGCCCGGGCCATGCACTACAGCAGTTCGCGCCGTGGCGGCCCGTTCGTGGCGCTCAACTGCGCG
GCGCTGCCCGAGGGGCTGATCGAGTCGGAGCTGTTCGGATACCAGGAGGGGGCCTTCACCGGTGCGAAGCGCAAGGGGTA
CAGCGGGAAGATCAGGCAGGCTGACGGCGGCACCCTGTTCCTGGACGAAATCGGCGACATGCCGCTCCTGTTCCAGGCCA
GGCTGCTCAGGGTGTTGCAGGAACGCAGCGTCTCGCCCCTTGGGGGGGCCGAATTGTACCAGGTGGACTTTGCCCTGATC
TGCGCCACCAACCGCAGGATGCGCCAGGAGGTGGAGGCCGGCAGGTTCCGCGAGGATCTCTACTATCGTCTCAACGGCCT
TTTGATAACCCTGCCACGATTGAGGCAGAGGATGGACCGTCTGGAGTTGGCCCGAACCATCATCGCCGGCTTGGTGCCTT
TCGGACGAACGGTCACCATGAGTAAGGGAGTCATGACGCTCTTCGAAAACCACCCCTGGCCGGGCAATATCCGTCAGATG
CACAGCGTGCTGCGCACGGCGGTGGCGCTTCTGGGCTATGACAGCGAGATCACCGTGGATCACCTGCCCGAGGATTTCAT
GGAGCAGAGCTCTTTGCAAGCCGACGCTTCCCCCCTTCGTGAACCGGACGCCCAGCGGCTGCTCTCCCCGCCCCAGGGGA
CCAGCCTGGAAAACATGGAAAAGAATGCCATCCGCGATGCGGTGCGCGAGTGCCGCGGGAACATGGCGGCCGCGGCGCGC
AGGCTGGGCATCAGCAGGAATACCCTCTACCGCAAGATGCAGGCGCTCTCCTGA

Upstream 100 bases:

>100_bases
TGTTTTTGGGTCTGGGTTATTGCTTTTGGGCATGCAATCTGCTAAAAGTTGAGGCCGATTCGTCGGGGCGGTCACCTCTG
GACGAAACAGGAGCATCGAT

Downstream 100 bases:

>100_bases
TACAGTCCTGAATACCAGGCACCTCTCCTTCACCCCCTTCTTCTCTGTCCTTGCCGCTCGCCATCCCTGTCCGCCATCCG
CTGCTCCTGGCGTCATCTGC

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MNKFPLVSLVKIKRARNFFFNQGAVPPGLVPEFIVRSWQRSLINGVPVDDESREIPLLTGRELTCAKEESRDLLNHSLPV
MENLYEQIIHTSSKVLLADASGVVLHSYGDPDFLGRTRKVSLLPGGIWSEGIRGTNAIGTSLVEQEPVVVHSAEHFIASN
HFLTCSASPIFDPFGRIMGVLDVSGDGRVHQPHTMALVRISVQQIENQMFSCGFEHDLVLHFHVRPEFVGTMYEGIAVFS
QDGKFLAANRNALQHLEMDRYQAESHCFSSLFNSPLAAIFDQPGQFPRPVQQLRTCTGITIYCRGKTRLINTSKIPLVMG
KPVSASPAPLGDAERKPLLEELELGDLGMQKLIARARKVLGHDIPVLLEGESGTGKELFARAMHYSSSRRGGPFVALNCA
ALPEGLIESELFGYQEGAFTGAKRKGYSGKIRQADGGTLFLDEIGDMPLLFQARLLRVLQERSVSPLGGAELYQVDFALI
CATNRRMRQEVEAGRFREDLYYRLNGLLITLPRLRQRMDRLELARTIIAGLVPFGRTVTMSKGVMTLFENHPWPGNIRQM
HSVLRTAVALLGYDSEITVDHLPEDFMEQSSLQADASPLREPDAQRLLSPPQGTSLENMEKNAIRDAVRECRGNMAAAAR
RLGISRNTLYRKMQALS

Sequences:

>Translated_657_residues
MNKFPLVSLVKIKRARNFFFNQGAVPPGLVPEFIVRSWQRSLINGVPVDDESREIPLLTGRELTCAKEESRDLLNHSLPV
MENLYEQIIHTSSKVLLADASGVVLHSYGDPDFLGRTRKVSLLPGGIWSEGIRGTNAIGTSLVEQEPVVVHSAEHFIASN
HFLTCSASPIFDPFGRIMGVLDVSGDGRVHQPHTMALVRISVQQIENQMFSCGFEHDLVLHFHVRPEFVGTMYEGIAVFS
QDGKFLAANRNALQHLEMDRYQAESHCFSSLFNSPLAAIFDQPGQFPRPVQQLRTCTGITIYCRGKTRLINTSKIPLVMG
KPVSASPAPLGDAERKPLLEELELGDLGMQKLIARARKVLGHDIPVLLEGESGTGKELFARAMHYSSSRRGGPFVALNCA
ALPEGLIESELFGYQEGAFTGAKRKGYSGKIRQADGGTLFLDEIGDMPLLFQARLLRVLQERSVSPLGGAELYQVDFALI
CATNRRMRQEVEAGRFREDLYYRLNGLLITLPRLRQRMDRLELARTIIAGLVPFGRTVTMSKGVMTLFENHPWPGNIRQM
HSVLRTAVALLGYDSEITVDHLPEDFMEQSSLQADASPLREPDAQRLLSPPQGTSLENMEKNAIRDAVRECRGNMAAAAR
RLGISRNTLYRKMQALS
>Mature_657_residues
MNKFPLVSLVKIKRARNFFFNQGAVPPGLVPEFIVRSWQRSLINGVPVDDESREIPLLTGRELTCAKEESRDLLNHSLPV
MENLYEQIIHTSSKVLLADASGVVLHSYGDPDFLGRTRKVSLLPGGIWSEGIRGTNAIGTSLVEQEPVVVHSAEHFIASN
HFLTCSASPIFDPFGRIMGVLDVSGDGRVHQPHTMALVRISVQQIENQMFSCGFEHDLVLHFHVRPEFVGTMYEGIAVFS
QDGKFLAANRNALQHLEMDRYQAESHCFSSLFNSPLAAIFDQPGQFPRPVQQLRTCTGITIYCRGKTRLINTSKIPLVMG
KPVSASPAPLGDAERKPLLEELELGDLGMQKLIARARKVLGHDIPVLLEGESGTGKELFARAMHYSSSRRGGPFVALNCA
ALPEGLIESELFGYQEGAFTGAKRKGYSGKIRQADGGTLFLDEIGDMPLLFQARLLRVLQERSVSPLGGAELYQVDFALI
CATNRRMRQEVEAGRFREDLYYRLNGLLITLPRLRQRMDRLELARTIIAGLVPFGRTVTMSKGVMTLFENHPWPGNIRQM
HSVLRTAVALLGYDSEITVDHLPEDFMEQSSLQADASPLREPDAQRLLSPPQGTSLENMEKNAIRDAVRECRGNMAAAAR
RLGISRNTLYRKMQALS

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=348, Percent_Identity=38.7931034482759, Blast_Score=232, Evalue=7e-62,
Organism=Escherichia coli, GI1790437, Length=313, Percent_Identity=43.7699680511182, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1788550, Length=318, Percent_Identity=39.937106918239, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI1788905, Length=308, Percent_Identity=39.6103896103896, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1790299, Length=320, Percent_Identity=40.3125, Blast_Score=202, Evalue=7e-53,
Organism=Escherichia coli, GI87082117, Length=335, Percent_Identity=39.4029850746269, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1786524, Length=346, Percent_Identity=38.728323699422, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI87082152, Length=312, Percent_Identity=37.5, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789087, Length=318, Percent_Identity=38.9937106918239, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI87081872, Length=314, Percent_Identity=37.2611464968153, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI87081858, Length=646, Percent_Identity=24.6130030959752, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1787583, Length=233, Percent_Identity=38.6266094420601, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1789828, Length=327, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 73026; Mature: 73026

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFPLVSLVKIKRARNFFFNQGAVPPGLVPEFIVRSWQRSLINGVPVDDESREIPLLTG
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEECC
RELTCAKEESRDLLNHSLPVMENLYEQIIHTSSKVLLADASGVVLHSYGDPDFLGRTRKV
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHCCCCEEE
SLLPGGIWSEGIRGTNAIGTSLVEQEPVVVHSAEHFIASNHFLTCSASPIFDPFGRIMGV
EECCCCHHHCCCCCCCHHHHHHHCCCCEEEECHHHHHHCCCEEEECCCCCHHHHHHHHEE
LDVSGDGRVHQPHTMALVRISVQQIENQMFSCGFEHDLVLHFHVRPEFVGTMYEGIAVFS
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHCEEEEE
QDGKFLAANRNALQHLEMDRYQAESHCFSSLFNSPLAAIFDQPGQFPRPVQQLRTCTGIT
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCEE
IYCRGKTRLINTSKIPLVMGKPVSASPAPLGDAERKPLLEELELGDLGMQKLIARARKVL
EEECCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
GHDIPVLLEGESGTGKELFARAMHYSSSRRGGPFVALNCAALPEGLIESELFGYQEGAFT
CCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCHHHHHHHHCCCCCCCC
GAKRKGYSGKIRQADGGTLFLDEIGDMPLLFQARLLRVLQERSVSPLGGAELYQVDFALI
CCCCCCCCCCEEECCCCEEEHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEE
CATNRRMRQEVEAGRFREDLYYRLNGLLITLPRLRQRMDRLELARTIIAGLVPFGRTVTM
EECCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
SKGVMTLFENHPWPGNIRQMHSVLRTAVALLGYDSEITVDHLPEDFMEQSSLQADASPLR
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHCCCCCCCCCC
EPDAQRLLSPPQGTSLENMEKNAIRDAVRECRGNMAAAARRLGISRNTLYRKMQALS
CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNKFPLVSLVKIKRARNFFFNQGAVPPGLVPEFIVRSWQRSLINGVPVDDESREIPLLTG
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEECC
RELTCAKEESRDLLNHSLPVMENLYEQIIHTSSKVLLADASGVVLHSYGDPDFLGRTRKV
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHCCCCEEE
SLLPGGIWSEGIRGTNAIGTSLVEQEPVVVHSAEHFIASNHFLTCSASPIFDPFGRIMGV
EECCCCHHHCCCCCCCHHHHHHHCCCCEEEECHHHHHHCCCEEEECCCCCHHHHHHHHEE
LDVSGDGRVHQPHTMALVRISVQQIENQMFSCGFEHDLVLHFHVRPEFVGTMYEGIAVFS
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHCEEEEE
QDGKFLAANRNALQHLEMDRYQAESHCFSSLFNSPLAAIFDQPGQFPRPVQQLRTCTGIT
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCEE
IYCRGKTRLINTSKIPLVMGKPVSASPAPLGDAERKPLLEELELGDLGMQKLIARARKVL
EEECCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
GHDIPVLLEGESGTGKELFARAMHYSSSRRGGPFVALNCAALPEGLIESELFGYQEGAFT
CCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCHHHHHHHHCCCCCCCC
GAKRKGYSGKIRQADGGTLFLDEIGDMPLLFQARLLRVLQERSVSPLGGAELYQVDFALI
CCCCCCCCCCEEECCCCEEEHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEE
CATNRRMRQEVEAGRFREDLYYRLNGLLITLPRLRQRMDRLELARTIIAGLVPFGRTVTM
EECCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
SKGVMTLFENHPWPGNIRQMHSVLRTAVALLGYDSEITVDHLPEDFMEQSSLQADASPLR
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHHHHCCCCCCCCCC
EPDAQRLLSPPQGTSLENMEKNAIRDAVRECRGNMAAAARRLGISRNTLYRKMQALS
CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]