Click here to switch to the map view.

The map label for this gene is pucD [H]

Identifier: 118579942

GI number: 118579942

Start: 1621845

End: 1624142

Strand: Reverse

Name: pucD [H]

Synonym: Ppro_1519

Alternate gene names: 118579942

Gene position: 1624142-1621845 (Counterclockwise)

Preceding gene: 118579943

Following gene: 118579941

Centisome position: 40.52

GC content: 68.06

Gene sequence:

>2298_bases
ATGACCATGGATGAACGACAACTGGAAATAGGCCGGCCGGAGATCCGCGGCGACGCCCCTGCCAAGGCCAGGGGTCGGGA
GCTGTTCTCCGCCGACATCTACCCCGACAACCTGGTCTGGGCAGGGGCGGTGCGGGCCGGCATCCCCCACGGCAGGCTCC
TGTCGCTGGATGCTTCGGCGGCCCTGGCCCTGCCCGGCGTGCTCAGGGTGCTGACCGCCAGGGACATAGACGGGCCGAAC
CGCCACGGCATCATCCATAAGGACACGCCGGTGCTGGTGGACGACCTGGTCCGCTACAGCGGAGACGCCATCGCCCTGGT
GCTGGCCGAGAGTGCCTCTGCCCTGCGCCGGGCCATCACGCTGGTGCGGGCCGAGATCCAGCCGCTTCCGGCGCTGTTCG
ACCCCGACGAGGCACTGGCCGAAGGCGCCCCCCAACTGCACCCGGACCAGGCGAGCAACCTGCTCCTGGCGGCCGAGATC
CGCACCGGCGACGCCGAGACGGCGCTGGGGGAGTGCGCCGCGATGGTGGAGGGAGAGTTCTCCACCCCGGTGCAGGCCCA
TGTTTTCCTGGAGACGGAGAACGGCACCGCCAGGCTGGAAGCGGATGGCGGCATCAGCATGACCGTCTCCACCCAGTCCC
CCTTCCGGGACCGCTTCGAGGTGGGCCATGCCCTGGGCATCCCTTTCCAGCGCATCCGCATCACAAGCCCCAGCCTGGGG
GGTGGCTTCGGCGGCAAGGACGGCGCCACCGTGCAGTGCCTGCTGGCACTGGCCGCCCTGCACAGCGAAGGGAGGCCGGT
GAGAATGCAGTGGAGCAGGGAGGAAAACCTGTCCGCCGGCTACCGGCGCCACGGCTGCAGGATGCGCTACCGCATGGGCG
CCTTGGAGGACGGCACCCTGCACGCCCTGCAGTGCGACCTGATCTATGACACCGGCGCCTACGCCCACCTGGGGGGCGAG
GTGATGGAGCTGGGCATGGAGCACAGCGGCGGCCCCTACCGCATCCCCCACACGCTGATCAGGGGAAAATGCGTCTTCAC
CAACAACCCGGTGGCCGGCGCCATGCGCGCCTTCGGCGTCTGCCAGGTCAGCTTCGCCTTCGAGTCCATGATGGACCTGC
TGGCGGAAAAGCTGGCCATGGACCCGCTGCAACTCCGCCGCAAGAACGCCCTGGTCCGGGGGGACAGAAACTGCGCCGGC
ATGCGCCTGGACACATCCACCAACATTGCAGGCTGCCTGGAACTGCTGGAGGAGCATCCCTTCTGGCACGAGCGGGAGGA
GTGGAAACGACAGGCACCTCCCCATACCAGGCGCGGGGTCGGTCTGGCGGCCATCTTCAACGCCGCCGGCTACGGCGGCA
AGGTGCGCGACGCGGCCATCGCCAAGGTGGAACTTTCCCCAGAGGGGGAGATCGTGGTGCACAACGGGGTCTCGGACATG
GGACAGGGAAACTCGGCCGCCTTCCTGCAGATGGCGGGACAGATCCTGGGACAGGATGCCTCCAGCTTGCGGCTGCACCA
GCCGGACACCCTCACCGCCTACCCCTCCGGTTCCTCATCCGCCGGCCGGACCACCTATACCTTCGGCAATGCCCTGATCA
AAGCCTGTCAGGATCTCAAGGCACGCCTGATCAACCGGGCCGGGCTGCTGCTGTTCACCGACAACGACGACGAGCTGCGC
CTGGCACCCGGCAAGGTGATCCACCCCCCAAGCCAGCGGGAAGTGCCCCTGCGGCAGTTGGCCGGCTTCATGCCCCGCGA
GGACCGGGTCTGCATCAACCAGTTCGTGGCCCCGGTCTGCCGGGATGTGCCGGATACGGCCACCGGCTTCTTCATCGGCT
TCCCCCACCTGATCTTCGCCTACGCCGCCCACTTGGCCCGCATCCAGGTGGACCTGGCCACCGGCCTGATCCGGGTGATG
GACTATCTGGCGACCACCGACGGCGGCGGAGTCATCAACCCGGCCATGTTCGACCAGCAGGTCCATGGCGGCGTGGCCCA
GGGTCTGGGCTACGCCCTGATGGAGGATCTGGTGACCAGCCAGGGGATGGTGCTGAGCGACGACCTGGGCAGCTATCTGA
TCCCGGGAGCCCAGGATGTGCCGGAGATCGTCTCCATCCCCTGCCAGGGCGACGAGGAGAGCGGCCCCTTCGGCATGAAG
GGCATCGGCGAGGTGGCCATGAACGGCCCGCTGCCGGCAATCGCCAACGCCCTGGCCGACGCCTGCGGGATCCGTGTCAA
CCATGCCCCGCTGACACCGTCGAAGGTGCTGGCGGCCCTTTCCGGCCTGAATGAATAG

Upstream 100 bases:

>100_bases
GCTGGATCCGCGTCACCCTCAAGGAGATGGAGGTCATGACCCGCTTTGCCCAGGCTCTGGGCGCTGAGATCGCGGCGATC
CGCTCGCGGGGTAGAACGTC

Downstream 100 bases:

>100_bases
CAGCAGGGAGTTTGCCATGGAATTCAAGGACCAGACCGTTGTCGTCACCGGCGGCACCCGCGGGATCGGACGGGCCATTG
CGCTGGCCTTTGCCCGCAAC

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 765; Mature: 764

Protein sequence:

>765_residues
MTMDERQLEIGRPEIRGDAPAKARGRELFSADIYPDNLVWAGAVRAGIPHGRLLSLDASAALALPGVLRVLTARDIDGPN
RHGIIHKDTPVLVDDLVRYSGDAIALVLAESASALRRAITLVRAEIQPLPALFDPDEALAEGAPQLHPDQASNLLLAAEI
RTGDAETALGECAAMVEGEFSTPVQAHVFLETENGTARLEADGGISMTVSTQSPFRDRFEVGHALGIPFQRIRITSPSLG
GGFGGKDGATVQCLLALAALHSEGRPVRMQWSREENLSAGYRRHGCRMRYRMGALEDGTLHALQCDLIYDTGAYAHLGGE
VMELGMEHSGGPYRIPHTLIRGKCVFTNNPVAGAMRAFGVCQVSFAFESMMDLLAEKLAMDPLQLRRKNALVRGDRNCAG
MRLDTSTNIAGCLELLEEHPFWHEREEWKRQAPPHTRRGVGLAAIFNAAGYGGKVRDAAIAKVELSPEGEIVVHNGVSDM
GQGNSAAFLQMAGQILGQDASSLRLHQPDTLTAYPSGSSSAGRTTYTFGNALIKACQDLKARLINRAGLLLFTDNDDELR
LAPGKVIHPPSQREVPLRQLAGFMPREDRVCINQFVAPVCRDVPDTATGFFIGFPHLIFAYAAHLARIQVDLATGLIRVM
DYLATTDGGGVINPAMFDQQVHGGVAQGLGYALMEDLVTSQGMVLSDDLGSYLIPGAQDVPEIVSIPCQGDEESGPFGMK
GIGEVAMNGPLPAIANALADACGIRVNHAPLTPSKVLAALSGLNE

Sequences:

>Translated_765_residues
MTMDERQLEIGRPEIRGDAPAKARGRELFSADIYPDNLVWAGAVRAGIPHGRLLSLDASAALALPGVLRVLTARDIDGPN
RHGIIHKDTPVLVDDLVRYSGDAIALVLAESASALRRAITLVRAEIQPLPALFDPDEALAEGAPQLHPDQASNLLLAAEI
RTGDAETALGECAAMVEGEFSTPVQAHVFLETENGTARLEADGGISMTVSTQSPFRDRFEVGHALGIPFQRIRITSPSLG
GGFGGKDGATVQCLLALAALHSEGRPVRMQWSREENLSAGYRRHGCRMRYRMGALEDGTLHALQCDLIYDTGAYAHLGGE
VMELGMEHSGGPYRIPHTLIRGKCVFTNNPVAGAMRAFGVCQVSFAFESMMDLLAEKLAMDPLQLRRKNALVRGDRNCAG
MRLDTSTNIAGCLELLEEHPFWHEREEWKRQAPPHTRRGVGLAAIFNAAGYGGKVRDAAIAKVELSPEGEIVVHNGVSDM
GQGNSAAFLQMAGQILGQDASSLRLHQPDTLTAYPSGSSSAGRTTYTFGNALIKACQDLKARLINRAGLLLFTDNDDELR
LAPGKVIHPPSQREVPLRQLAGFMPREDRVCINQFVAPVCRDVPDTATGFFIGFPHLIFAYAAHLARIQVDLATGLIRVM
DYLATTDGGGVINPAMFDQQVHGGVAQGLGYALMEDLVTSQGMVLSDDLGSYLIPGAQDVPEIVSIPCQGDEESGPFGMK
GIGEVAMNGPLPAIANALADACGIRVNHAPLTPSKVLAALSGLNE
>Mature_764_residues
TMDERQLEIGRPEIRGDAPAKARGRELFSADIYPDNLVWAGAVRAGIPHGRLLSLDASAALALPGVLRVLTARDIDGPNR
HGIIHKDTPVLVDDLVRYSGDAIALVLAESASALRRAITLVRAEIQPLPALFDPDEALAEGAPQLHPDQASNLLLAAEIR
TGDAETALGECAAMVEGEFSTPVQAHVFLETENGTARLEADGGISMTVSTQSPFRDRFEVGHALGIPFQRIRITSPSLGG
GFGGKDGATVQCLLALAALHSEGRPVRMQWSREENLSAGYRRHGCRMRYRMGALEDGTLHALQCDLIYDTGAYAHLGGEV
MELGMEHSGGPYRIPHTLIRGKCVFTNNPVAGAMRAFGVCQVSFAFESMMDLLAEKLAMDPLQLRRKNALVRGDRNCAGM
RLDTSTNIAGCLELLEEHPFWHEREEWKRQAPPHTRRGVGLAAIFNAAGYGGKVRDAAIAKVELSPEGEIVVHNGVSDMG
QGNSAAFLQMAGQILGQDASSLRLHQPDTLTAYPSGSSSAGRTTYTFGNALIKACQDLKARLINRAGLLLFTDNDDELRL
APGKVIHPPSQREVPLRQLAGFMPREDRVCINQFVAPVCRDVPDTATGFFIGFPHLIFAYAAHLARIQVDLATGLIRVMD
YLATTDGGGVINPAMFDQQVHGGVAQGLGYALMEDLVTSQGMVLSDDLGSYLIPGAQDVPEIVSIPCQGDEESGPFGMKG
IGEVAMNGPLPAIANALADACGIRVNHAPLTPSKVLAALSGLNE

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=715, Percent_Identity=26.7132867132867, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI71773480, Length=790, Percent_Identity=24.1772151898734, Blast_Score=166, Evalue=7e-41,
Organism=Escherichia coli, GI1789230, Length=761, Percent_Identity=30.6176084099869, Blast_Score=309, Evalue=5e-85,
Organism=Escherichia coli, GI1789246, Length=806, Percent_Identity=25.682382133995, Blast_Score=215, Evalue=7e-57,
Organism=Escherichia coli, GI1786478, Length=768, Percent_Identity=26.953125, Blast_Score=180, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17540638, Length=773, Percent_Identity=26.0025873221216, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17539860, Length=743, Percent_Identity=23.5531628532974, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32566215, Length=725, Percent_Identity=22.4827586206897, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI17737937, Length=714, Percent_Identity=26.6106442577031, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24647199, Length=682, Percent_Identity=23.4604105571848, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24647193, Length=748, Percent_Identity=23.3957219251337, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24647201, Length=721, Percent_Identity=23.3009708737864, Blast_Score=116, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 81905; Mature: 81773

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMDERQLEIGRPEIRGDAPAKARGRELFSADIYPDNLVWAGAVRAGIPHGRLLSLDASA
CCCCCCHHHCCCCCCCCCCCCHHCCCEEEECCCCCCCEEEECHHHCCCCCCEEEEECCCH
ALALPGVLRVLTARDIDGPNRHGIIHKDTPVLVDDLVRYSGDAIALVLAESASALRRAIT
HHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHHH
LVRAEIQPLPALFDPDEALAEGAPQLHPDQASNLLLAAEIRTGDAETALGECAAMVEGEF
HHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCC
STPVQAHVFLETENGTARLEADGGISMTVSTQSPFRDRFEVGHALGIPFQRIRITSPSLG
CCCEEEEEEEEECCCEEEEEECCCEEEEEECCCCCHHHHHCCHHCCCCCEEEEEECCCCC
GGFGGKDGATVQCLLALAALHSEGRPVRMQWSREENLSAGYRRHGCRMRYRMGALEDGTL
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCCEEEEECCCCCCCCE
HALQCDLIYDTGAYAHLGGEVMELGMEHSGGPYRIPHTLIRGKCVFTNNPVAGAMRAFGV
EEEEEEEEEECCCHHHHCHHHHHHCCCCCCCCEECCHHHHCCEEEEECCCHHHHHHHHHH
CQVSFAFESMMDLLAEKLAMDPLQLRRKNALVRGDRNCAGMRLDTSTNIAGCLELLEEHP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCEEECCCCCHHHHHHHHHHCC
FWHEREEWKRQAPPHTRRGVGLAAIFNAAGYGGKVRDAAIAKVELSPEGEIVVHNGVSDM
CCCCHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCC
GQGNSAAFLQMAGQILGQDASSLRLHQPDTLTAYPSGSSSAGRTTYTFGNALIKACQDLK
CCCCCHHHHHHHHHHHCCCCHHCEEECCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHH
ARLINRAGLLLFTDNDDELRLAPGKVIHPPSQREVPLRQLAGFMPREDRVCINQFVAPVC
HHHHHHCCEEEEECCCCCEEECCCCEECCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
RDVPDTATGFFIGFPHLIFAYAAHLARIQVDLATGLIRVMDYLATTDGGGVINPAMFDQQ
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
VHGGVAQGLGYALMEDLVTSQGMVLSDDLGSYLIPGAQDVPEIVSIPCQGDEESGPFGMK
HHCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
GIGEVAMNGPLPAIANALADACGIRVNHAPLTPSKVLAALSGLNE
CHHHHHCCCCHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TMDERQLEIGRPEIRGDAPAKARGRELFSADIYPDNLVWAGAVRAGIPHGRLLSLDASA
CCCCCHHHCCCCCCCCCCCCHHCCCEEEECCCCCCCEEEECHHHCCCCCCEEEEECCCH
ALALPGVLRVLTARDIDGPNRHGIIHKDTPVLVDDLVRYSGDAIALVLAESASALRRAIT
HHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHHH
LVRAEIQPLPALFDPDEALAEGAPQLHPDQASNLLLAAEIRTGDAETALGECAAMVEGEF
HHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCC
STPVQAHVFLETENGTARLEADGGISMTVSTQSPFRDRFEVGHALGIPFQRIRITSPSLG
CCCEEEEEEEEECCCEEEEEECCCEEEEEECCCCCHHHHHCCHHCCCCCEEEEEECCCCC
GGFGGKDGATVQCLLALAALHSEGRPVRMQWSREENLSAGYRRHGCRMRYRMGALEDGTL
CCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHCCEEEEECCCCCCCCE
HALQCDLIYDTGAYAHLGGEVMELGMEHSGGPYRIPHTLIRGKCVFTNNPVAGAMRAFGV
EEEEEEEEEECCCHHHHCHHHHHHCCCCCCCCEECCHHHHCCEEEEECCCHHHHHHHHHH
CQVSFAFESMMDLLAEKLAMDPLQLRRKNALVRGDRNCAGMRLDTSTNIAGCLELLEEHP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCEEECCCCCHHHHHHHHHHCC
FWHEREEWKRQAPPHTRRGVGLAAIFNAAGYGGKVRDAAIAKVELSPEGEIVVHNGVSDM
CCCCHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCC
GQGNSAAFLQMAGQILGQDASSLRLHQPDTLTAYPSGSSSAGRTTYTFGNALIKACQDLK
CCCCCHHHHHHHHHHHCCCCHHCEEECCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHH
ARLINRAGLLLFTDNDDELRLAPGKVIHPPSQREVPLRQLAGFMPREDRVCINQFVAPVC
HHHHHHCCEEEEECCCCCEEECCCCEECCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
RDVPDTATGFFIGFPHLIFAYAAHLARIQVDLATGLIRVMDYLATTDGGGVINPAMFDQQ
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
VHGGVAQGLGYALMEDLVTSQGMVLSDDLGSYLIPGAQDVPEIVSIPCQGDEESGPFGMK
HHCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
GIGEVAMNGPLPAIANALADACGIRVNHAPLTPSKVLAALSGLNE
CHHHHHCCCCHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]