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The map label for this gene is bioB [H]

Identifier: 118579915

GI number: 118579915

Start: 1599288

End: 1600361

Strand: Direct

Name: bioB [H]

Synonym: Ppro_1491

Alternate gene names: 118579915

Gene position: 1599288-1600361 (Clockwise)

Preceding gene: 118579914

Following gene: 118579916

Centisome position: 39.9

GC content: 62.01

Gene sequence:

>1074_bases
ATGGAAAAACAGGAGATTCTTCGCTGGCTGCGTACCACGGGCGAGGATCGGCTCTCACGATTGTGGCAGATGGCTGATCA
GGCGCGGCGGCGGCATGTGGGGCAGGATGTTCATCTCAGGGGGCTGATCGAAATATCCAACCACTGCTCCCGCAGGTGCG
GCTACTGCGGCTTGAACGTGCATAACAGCAGTATCGGGCGTTACCGCATGACGGATGATGAAATTGTCGCCTGCGCTCAT
CAGGCGTCAGCCCTTGGCTATGGCACGGTCGTCATGCAGGCCGGTGAGGACCCTGGTATCGGCAAGCAGTGGATGCACGA
CCTGATCCGCCGTATAAAGCGCGAGACGGATCTGGCCGTGACGCTCAGCCTGGGCGAGCGGCCGGATGAAGAGCTTTGCA
GCTGGTTTGATGCCGGTGCTGATCGCTATCTGCTGCGGTTCGAAACCTCCCGGAGGAGCCTGTACGACAGCATCCATCCG
CCGTTAGCGGGAACGATGTCCGACCGAATAGCCCTGCTCCGCAGGCTCAAACTGTTCGGTTATGAAATCGGCAGCGGCGT
CATGATCGGCATTCCGGGACAGACCTATGACGATCTTGCCACCGACATCCTCCTGTTCAAGGAGCTTGACCTGGACATGA
TCGGAGTCGGCCCGTTCATCCCGCACCAGGCCACGCCGCTGGGCAGGCCCGACCAGGTTGCGTACGCCGTCCCGGCGGAA
CAGGTTCCCAACTCCGAAGAGATGACCTACAAGGTGATCGCCCTGAGCCGACTGCTCTGCCTCCGGGCCAACATCCCCAG
CACCACCGCCCTTGCCACCATCAACTCCGAGTCGGGGCGGGAGCTGGGCCTGTCCCGGGGCGCCAACGTTGTCATGCCCA
ATGTGACCCCTGGAGCGTACCGCGCCCTGTACGAGATTTACCCCTCAAAAGCCTGTGTCGACGAGACCGCGGCAGACTTC
GGATCAGGTCTCGTGCGCAGGATTCGCTCCATGGGCAGAACCATCGGCAGGGGGCGCGGCGATTCACCCAACCTGTCCGG
GCGAAAGAGCCGCACGAGCGAGGTGCTGCCATGA

Upstream 100 bases:

>100_bases
GGCGTTGCAGCAGGGGAGGGGGCTGGTGTCGCGCCCACAACCATTGGCAAGGGGCACGAGCAGCAGTGAGAAGATAACGG
GAAAAGCTATCAAAACAGGC

Downstream 100 bases:

>100_bases
GTTCCCTGCCATCCATGAAACTGAGCGCAGGCGCCGCCGACTTCATCGACGAGGCGTATCTGTTCGGCCTTCTGGGAGGC
AAGCGTCCCGAAGCGGCACG

Product: biotin synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MEKQEILRWLRTTGEDRLSRLWQMADQARRRHVGQDVHLRGLIEISNHCSRRCGYCGLNVHNSSIGRYRMTDDEIVACAH
QASALGYGTVVMQAGEDPGIGKQWMHDLIRRIKRETDLAVTLSLGERPDEELCSWFDAGADRYLLRFETSRRSLYDSIHP
PLAGTMSDRIALLRRLKLFGYEIGSGVMIGIPGQTYDDLATDILLFKELDLDMIGVGPFIPHQATPLGRPDQVAYAVPAE
QVPNSEEMTYKVIALSRLLCLRANIPSTTALATINSESGRELGLSRGANVVMPNVTPGAYRALYEIYPSKACVDETAADF
GSGLVRRIRSMGRTIGRGRGDSPNLSGRKSRTSEVLP

Sequences:

>Translated_357_residues
MEKQEILRWLRTTGEDRLSRLWQMADQARRRHVGQDVHLRGLIEISNHCSRRCGYCGLNVHNSSIGRYRMTDDEIVACAH
QASALGYGTVVMQAGEDPGIGKQWMHDLIRRIKRETDLAVTLSLGERPDEELCSWFDAGADRYLLRFETSRRSLYDSIHP
PLAGTMSDRIALLRRLKLFGYEIGSGVMIGIPGQTYDDLATDILLFKELDLDMIGVGPFIPHQATPLGRPDQVAYAVPAE
QVPNSEEMTYKVIALSRLLCLRANIPSTTALATINSESGRELGLSRGANVVMPNVTPGAYRALYEIYPSKACVDETAADF
GSGLVRRIRSMGRTIGRGRGDSPNLSGRKSRTSEVLP
>Mature_357_residues
MEKQEILRWLRTTGEDRLSRLWQMADQARRRHVGQDVHLRGLIEISNHCSRRCGYCGLNVHNSSIGRYRMTDDEIVACAH
QASALGYGTVVMQAGEDPGIGKQWMHDLIRRIKRETDLAVTLSLGERPDEELCSWFDAGADRYLLRFETSRRSLYDSIHP
PLAGTMSDRIALLRRLKLFGYEIGSGVMIGIPGQTYDDLATDILLFKELDLDMIGVGPFIPHQATPLGRPDQVAYAVPAE
QVPNSEEMTYKVIALSRLLCLRANIPSTTALATINSESGRELGLSRGANVVMPNVTPGAYRALYEIYPSKACVDETAADF
GSGLVRRIRSMGRTIGRGRGDSPNLSGRKSRTSEVLP

Specific function: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism [H]

COG id: COG0502

COG function: function code H; Biotin synthase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Biotin synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR010722
- InterPro:   IPR002684
- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06968 BATS; PF04055 Radical_SAM [H]

EC number: =2.8.1.6 [H]

Molecular weight: Translated: 39662; Mature: 39662

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQEILRWLRTTGEDRLSRLWQMADQARRRHVGQDVHLRGLIEISNHCSRRCGYCGLNV
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEE
HNSSIGRYRMTDDEIVACAHQASALGYGTVVMQAGEDPGIGKQWMHDLIRRIKRETDLAV
CCCCCCCEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEE
TLSLGERPDEELCSWFDAGADRYLLRFETSRRSLYDSIHPPLAGTMSDRIALLRRLKLFG
EEECCCCCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
YEIGSGVMIGIPGQTYDDLATDILLFKELDLDMIGVGPFIPHQATPLGRPDQVAYAVPAE
EECCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCEEEECCHH
QVPNSEEMTYKVIALSRLLCLRANIPSTTALATINSESGRELGLSRGANVVMPNVTPGAY
HCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCEEECCCCCHHH
RALYEIYPSKACVDETAADFGSGLVRRIRSMGRTIGRGRGDSPNLSGRKSRTSEVLP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEKQEILRWLRTTGEDRLSRLWQMADQARRRHVGQDVHLRGLIEISNHCSRRCGYCGLNV
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEE
HNSSIGRYRMTDDEIVACAHQASALGYGTVVMQAGEDPGIGKQWMHDLIRRIKRETDLAV
CCCCCCCEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEE
TLSLGERPDEELCSWFDAGADRYLLRFETSRRSLYDSIHPPLAGTMSDRIALLRRLKLFG
EEECCCCCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
YEIGSGVMIGIPGQTYDDLATDILLFKELDLDMIGVGPFIPHQATPLGRPDQVAYAVPAE
EECCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCEEEECCHH
QVPNSEEMTYKVIALSRLLCLRANIPSTTALATINSESGRELGLSRGANVVMPNVTPGAY
HCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCEEECCCCCHHH
RALYEIYPSKACVDETAADFGSGLVRRIRSMGRTIGRGRGDSPNLSGRKSRTSEVLP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA