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The map label for this gene is nuoG [C]

Identifier: 118579914

GI number: 118579914

Start: 1597451

End: 1599256

Strand: Direct

Name: nuoG [C]

Synonym: Ppro_1490

Alternate gene names: 118579914

Gene position: 1597451-1599256 (Clockwise)

Preceding gene: 118579913

Following gene: 118579915

Centisome position: 39.86

GC content: 56.15

Gene sequence:

>1806_bases
ATGACCAGATTTGCCGATACTACTGTCTACATAAACAATCGACCGGTCGTTATGGAGGGGGAGCGAAACCTGCTTGAATT
GATCCGCAAGACCGGAATCGATCTGCCTACATTCTGCTACCAATCGGATCTGAGCGTTTACGGCTCGTGCCGTCTCTGCC
TGGTGGAGATCGAGGGGCGCGGTATCGTGGGCTCCTGTTCCACCCCGCCGGAAGCCGGCATGAGGGTTCATACCCATACC
GAGGAAATCCGCGAACTCCGAAAGATAGCCATTGAACTGTTTCTTGCAAACCATGACAGCAATTGCCCCACCTGCCTGAA
GAGTGACGATTGCCAGTTGCAGAATCTTGCCCGTCGACTGGGGGTCGATGCGGTTCGTTTTCAGTCGGTGCTGGTCAAAA
AGCCGATTGACAACTCTTCGCCAGCCATCATACGGGATCCCAACAAATGCGTGCTGTGCGGTGACTGCGCCCGCATGTGC
TCGGAGATACAGGGCATCGGTGCCATCGATTTTGCCCACCGCGGCCACGATGCCGCCGTATTGCCCGCATTCGGCAAAAA
GATCGGAGAGGTTGAATGCGTTAATTGCGGCCAGTGCACCATTGTGTGCCCAACCGGTTCACTTTGCCTGAAGCCTGAGA
TGGAAGAGGTGTGGAAGTCGCTCACCGATAAGCAAACCTACACCGTGGCGGCAATCGCTCCGGCCGTCCGGGTCGCCATC
GGTGAAATATTCGGTATGGAGGCGGGAGCCGTCTCCACGGGACAGATGCTTGCAGCGTTGAAACTGCTCGGTTTTGACCA
GGTGTACGATGTTTCTTTCGCAGCGGATCTCACGACCATCGAAGAGGGCAGCGAGTTTCTGGAGCGGAGAAGCGCCGGTG
TCAGGCTGCCGCACTTTACCTCCTGCTGCCCGGCCTGGGTCAAGTACGTCGAGCATTTTCATCCACACCTGATCGGGAAT
CTCTCCACCTGCAAGTCGCCGCTGCAGATGTTCGGCGCGCTGCTGAAAGATCGTCTTCCTGACCTGGTGCAGATACCAAG
GGAACGGGTGAAGGTCGTTTCCATCACCCCCTGTACCGCCAAGAAGTTTGAGGCGAAGAGGCCTGAATTCACCCATGACG
GCATCCCGGATATCGACCACGTTATCACGACCATAGAACTTGGCAGGATGATCAAGGCTGCCGGCATCCAGTTCAATGAT
CTGTCTCCCGAATCCTTTGACATGCCATTCGGTTTCTCCACCAGTGCCGGCGTGATATTCGGCAACTCCGGTGGCGTTAC
CGAGGCTGTCCTGCGCTTCACCATGGAGAAGCTGAGCAACAAGCCGCTTGCAAAGCTTGATTTTGTGGAAGTGCGCGGCG
AGTCCGGAATCCGCGAGGCGTCATTCGACATTGGCGGCAGCACAATCAGGTTTGCCATCGTCCATGGCCTGAAGAACGCC
AAGATGCTGATCACTAAAATTGCCGCCGGCAAGTGCGCCTATGACTTTGTTGAAGTCATGGCCTGTCCCCAGGGATGCAT
CAATGGCGGAGGGCAGCCGGTGAATCACGTTTACAACTACAAGCAACTTCGTACCAGGGGCCTTTTCACGGCGGGCAAGA
TGTTCCACCTGCATAAACCGCAGGATAACATCATGGTAAACGAATGCTATCAACAGTATCTGGGTGATGTGGGGGGGGCG
AAGGCTCAACAGTTGTTGCACACACACTACAAAAACCGTCGTCGGCAAACGGAGGATGGCGTTGCAGCAGGGGAGGGGGC
TGGTGTCGCGCCCACAACCATTGGCAAGGGGCACGAGCAGCAGTGA

Upstream 100 bases:

>100_bases
AAGCAGTGTCCTACCGGCCAGTGCAGTCTTCTCACTAAACCGGACAGGGTGACTGCATGAGCAGGAGATGGGCAGCACAG
TGCGCCAGGGAGTGTGAGTA

Downstream 100 bases:

>100_bases
GAAGATAACGGGAAAAGCTATCAAAACAGGCATGGAAAAACAGGAGATTCTTCGCTGGCTGCGTACCACGGGCGAGGATC
GGCTCTCACGATTGTGGCAG

Product: hydrogenases, Fe-only

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTRFADTTVYINNRPVVMEGERNLLELIRKTGIDLPTFCYQSDLSVYGSCRLCLVEIEGRGIVGSCSTPPEAGMRVHTHT
EEIRELRKIAIELFLANHDSNCPTCLKSDDCQLQNLARRLGVDAVRFQSVLVKKPIDNSSPAIIRDPNKCVLCGDCARMC
SEIQGIGAIDFAHRGHDAAVLPAFGKKIGEVECVNCGQCTIVCPTGSLCLKPEMEEVWKSLTDKQTYTVAAIAPAVRVAI
GEIFGMEAGAVSTGQMLAALKLLGFDQVYDVSFAADLTTIEEGSEFLERRSAGVRLPHFTSCCPAWVKYVEHFHPHLIGN
LSTCKSPLQMFGALLKDRLPDLVQIPRERVKVVSITPCTAKKFEAKRPEFTHDGIPDIDHVITTIELGRMIKAAGIQFND
LSPESFDMPFGFSTSAGVIFGNSGGVTEAVLRFTMEKLSNKPLAKLDFVEVRGESGIREASFDIGGSTIRFAIVHGLKNA
KMLITKIAAGKCAYDFVEVMACPQGCINGGGQPVNHVYNYKQLRTRGLFTAGKMFHLHKPQDNIMVNECYQQYLGDVGGA
KAQQLLHTHYKNRRRQTEDGVAAGEGAGVAPTTIGKGHEQQ

Sequences:

>Translated_601_residues
MTRFADTTVYINNRPVVMEGERNLLELIRKTGIDLPTFCYQSDLSVYGSCRLCLVEIEGRGIVGSCSTPPEAGMRVHTHT
EEIRELRKIAIELFLANHDSNCPTCLKSDDCQLQNLARRLGVDAVRFQSVLVKKPIDNSSPAIIRDPNKCVLCGDCARMC
SEIQGIGAIDFAHRGHDAAVLPAFGKKIGEVECVNCGQCTIVCPTGSLCLKPEMEEVWKSLTDKQTYTVAAIAPAVRVAI
GEIFGMEAGAVSTGQMLAALKLLGFDQVYDVSFAADLTTIEEGSEFLERRSAGVRLPHFTSCCPAWVKYVEHFHPHLIGN
LSTCKSPLQMFGALLKDRLPDLVQIPRERVKVVSITPCTAKKFEAKRPEFTHDGIPDIDHVITTIELGRMIKAAGIQFND
LSPESFDMPFGFSTSAGVIFGNSGGVTEAVLRFTMEKLSNKPLAKLDFVEVRGESGIREASFDIGGSTIRFAIVHGLKNA
KMLITKIAAGKCAYDFVEVMACPQGCINGGGQPVNHVYNYKQLRTRGLFTAGKMFHLHKPQDNIMVNECYQQYLGDVGGA
KAQQLLHTHYKNRRRQTEDGVAAGEGAGVAPTTIGKGHEQQ
>Mature_600_residues
TRFADTTVYINNRPVVMEGERNLLELIRKTGIDLPTFCYQSDLSVYGSCRLCLVEIEGRGIVGSCSTPPEAGMRVHTHTE
EIRELRKIAIELFLANHDSNCPTCLKSDDCQLQNLARRLGVDAVRFQSVLVKKPIDNSSPAIIRDPNKCVLCGDCARMCS
EIQGIGAIDFAHRGHDAAVLPAFGKKIGEVECVNCGQCTIVCPTGSLCLKPEMEEVWKSLTDKQTYTVAAIAPAVRVAIG
EIFGMEAGAVSTGQMLAALKLLGFDQVYDVSFAADLTTIEEGSEFLERRSAGVRLPHFTSCCPAWVKYVEHFHPHLIGNL
STCKSPLQMFGALLKDRLPDLVQIPRERVKVVSITPCTAKKFEAKRPEFTHDGIPDIDHVITTIELGRMIKAAGIQFNDL
SPESFDMPFGFSTSAGVIFGNSGGVTEAVLRFTMEKLSNKPLAKLDFVEVRGESGIREASFDIGGSTIRFAIVHGLKNAK
MLITKIAAGKCAYDFVEVMACPQGCINGGGQPVNHVYNYKQLRTRGLFTAGKMFHLHKPQDNIMVNECYQQYLGDVGGAK
AQQLLHTHYKNRRRQTEDGVAAGEGAGVAPTTIGKGHEQQ

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=415, Percent_Identity=29.8795180722892, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI134284357, Length=382, Percent_Identity=29.0575916230367, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI6912524, Length=414, Percent_Identity=27.7777777777778, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI84452151, Length=372, Percent_Identity=29.0322580645161, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI14165461, Length=463, Percent_Identity=25.4859611231102, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI33519475, Length=205, Percent_Identity=32.6829268292683, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI145693161, Length=221, Percent_Identity=28.5067873303167, Blast_Score=96, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI32566231, Length=207, Percent_Identity=30.9178743961353, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17565758, Length=207, Percent_Identity=30.9178743961353, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193209088, Length=207, Percent_Identity=30.9178743961353, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71995015, Length=407, Percent_Identity=27.5184275184275, Blast_Score=102, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6324089, Length=384, Percent_Identity=24.21875, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI116007464, Length=404, Percent_Identity=27.970297029703, Blast_Score=155, Evalue=9e-38,
Organism=Drosophila melanogaster, GI116007468, Length=404, Percent_Identity=27.970297029703, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI116007470, Length=404, Percent_Identity=27.970297029703, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI116007466, Length=404, Percent_Identity=27.970297029703, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI116007462, Length=284, Percent_Identity=30.6338028169014, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24640559, Length=209, Percent_Identity=30.622009569378, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24640557, Length=209, Percent_Identity=30.622009569378, Blast_Score=112, Evalue=8e-25,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 65761; Mature: 65629

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFADTTVYINNRPVVMEGERNLLELIRKTGIDLPTFCYQSDLSVYGSCRLCLVEIEGR
CCCEECEEEEECCCEEEECCCHHHHHHHHHCCCCCCHHHHHCCCCEECCEEEEEEEEECC
GIVGSCSTPPEAGMRVHTHTEEIRELRKIAIELFLANHDSNCPTCLKSDDCQLQNLARRL
EEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHH
GVDAVRFQSVLVKKPIDNSSPAIIRDPNKCVLCGDCARMCSEIQGIGAIDFAHRGHDAAV
CCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEHHHHHHHHHHCCCCCEEHHCCCCCCEE
LPAFGKKIGEVECVNCGQCTIVCPTGSLCLKPEMEEVWKSLTDKQTYTVAAIAPAVRVAI
ECHHHHCCCCEEEECCCCEEEECCCCCEECCCCHHHHHHHHCCCCEEEEHHHHHHHHHHH
GEIFGMEAGAVSTGQMLAALKLLGFDQVYDVSFAADLTTIEEGSEFLERRSAGVRLPHFT
HHHHCCCCCCCCHHHHHHHHHHHCCCHHCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHH
SCCPAWVKYVEHFHPHLIGNLSTCKSPLQMFGALLKDRLPDLVQIPRERVKVVSITPCTA
HHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHHEEEEEECCCCC
KKFEAKRPEFTHDGIPDIDHVITTIELGRMIKAAGIQFNDLSPESFDMPFGFSTSAGVIF
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCEEE
GNSGGVTEAVLRFTMEKLSNKPLAKLDFVEVRGESGIREASFDIGGSTIRFAIVHGLKNA
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHCCCCC
KMLITKIAAGKCAYDFVEVMACPQGCINGGGQPVNHVYNYKQLRTRGLFTAGKMFHLHKP
HHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHCCEEECCEEEEECC
QDNIMVNECYQQYLGDVGGAKAQQLLHTHYKNRRRQTEDGVAAGEGAGVAPTTIGKGHEQ
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
Q
C
>Mature Secondary Structure 
TRFADTTVYINNRPVVMEGERNLLELIRKTGIDLPTFCYQSDLSVYGSCRLCLVEIEGR
CCEECEEEEECCCEEEECCCHHHHHHHHHCCCCCCHHHHHCCCCEECCEEEEEEEEECC
GIVGSCSTPPEAGMRVHTHTEEIRELRKIAIELFLANHDSNCPTCLKSDDCQLQNLARRL
EEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHH
GVDAVRFQSVLVKKPIDNSSPAIIRDPNKCVLCGDCARMCSEIQGIGAIDFAHRGHDAAV
CCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEHHHHHHHHHHCCCCCEEHHCCCCCCEE
LPAFGKKIGEVECVNCGQCTIVCPTGSLCLKPEMEEVWKSLTDKQTYTVAAIAPAVRVAI
ECHHHHCCCCEEEECCCCEEEECCCCCEECCCCHHHHHHHHCCCCEEEEHHHHHHHHHHH
GEIFGMEAGAVSTGQMLAALKLLGFDQVYDVSFAADLTTIEEGSEFLERRSAGVRLPHFT
HHHHCCCCCCCCHHHHHHHHHHHCCCHHCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHH
SCCPAWVKYVEHFHPHLIGNLSTCKSPLQMFGALLKDRLPDLVQIPRERVKVVSITPCTA
HHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHCCHHHEEEEEECCCCC
KKFEAKRPEFTHDGIPDIDHVITTIELGRMIKAAGIQFNDLSPESFDMPFGFSTSAGVIF
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCEEE
GNSGGVTEAVLRFTMEKLSNKPLAKLDFVEVRGESGIREASFDIGGSTIRFAIVHGLKNA
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHCCCCC
KMLITKIAAGKCAYDFVEVMACPQGCINGGGQPVNHVYNYKQLRTRGLFTAGKMFHLHKP
HHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHCCEEECCEEEEECC
QDNIMVNECYQQYLGDVGGAKAQQLLHTHYKNRRRQTEDGVAAGEGAGVAPTTIGKGHEQ
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]