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The map label for this gene is nuoE2 [H]

Identifier: 118579912

GI number: 118579912

Start: 1595192

End: 1595701

Strand: Direct

Name: nuoE2 [H]

Synonym: Ppro_1488

Alternate gene names: 118579912

Gene position: 1595192-1595701 (Clockwise)

Preceding gene: 118579911

Following gene: 118579913

Centisome position: 39.8

GC content: 54.31

Gene sequence:

>510_bases
ATGTCACCCTGTACTGAACACGTTGCCGCAACGACTCGAAAATTTCCAGAAGTCGACCTGATTCTGGAAAAGTACGACCA
CCAGCCTGCCCGGCTGACCCTGATCCTTCAGGCAATACAGGATGAGTACCGTTATCTGCCGATGGAGGTCCTTTCACACG
TCATCGAGGAACTGGACATACCGGCAACAAAGGTGTTCGGTGTTGTTTCGTTTTATGCGCATTTTACCCTGGAACCGCGC
GGCAAATATGTCATTCGGCTGTGTGACGGCACGGCCTGCCATGCCAAGCGTTCGATCCCCATACTGGAAGCCCTGTATGC
AAAACTGGGCCTGAGCAGCAAAAAGGTAACCACCCCTGACATGCTGTTTACCGTTGAGACGGTCACCTGTCTCGGCGCCT
GCGGTCTTGCGCCGGTTATGCTTATCAACGAGGAAGTCTATGGCCGGGTGACTCCCGCCAGCGCGGTGGCGCTGATTGAT
GAAATCATTGCAAAGGAGGCAAACGCGTGA

Upstream 100 bases:

>100_bases
CGTGAAAGAAGACTACCAGGGGACTTTTCAGCTGGCCGCTTGTGCGGTCCGGAAAGACCCTATCACCTGTTGTGGGAATT
CGGAGGAGATAAAGAGAAAC

Downstream 100 bases:

>100_bases
GTCACGTTAAATCCTCCGTTCAAACGGGCTCAAAGCGGCGCATCATCATCTGTGCCGGCACCGGCTGTGTCTCCAGTGGG
GCACTCAAGGTCCATGGGGC

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E 2; NDH-1 subunit E 2 [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSPCTEHVAATTRKFPEVDLILEKYDHQPARLTLILQAIQDEYRYLPMEVLSHVIEELDIPATKVFGVVSFYAHFTLEPR
GKYVIRLCDGTACHAKRSIPILEALYAKLGLSSKKVTTPDMLFTVETVTCLGACGLAPVMLINEEVYGRVTPASAVALID
EIIAKEANA

Sequences:

>Translated_169_residues
MSPCTEHVAATTRKFPEVDLILEKYDHQPARLTLILQAIQDEYRYLPMEVLSHVIEELDIPATKVFGVVSFYAHFTLEPR
GKYVIRLCDGTACHAKRSIPILEALYAKLGLSSKKVTTPDMLFTVETVTCLGACGLAPVMLINEEVYGRVTPASAVALID
EIIAKEANA
>Mature_168_residues
SPCTEHVAATTRKFPEVDLILEKYDHQPARLTLILQAIQDEYRYLPMEVLSHVIEELDIPATKVFGVVSFYAHFTLEPRG
KYVIRLCDGTACHAKRSIPILEALYAKLGLSSKKVTTPDMLFTVETVTCLGACGLAPVMLINEEVYGRVTPASAVALIDE
IIAKEANA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=156, Percent_Identity=35.8974358974359, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1788621, Length=160, Percent_Identity=29.375, Blast_Score=80, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17561328, Length=156, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18859877, Length=157, Percent_Identity=32.484076433121, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355353, Length=113, Percent_Identity=35.3982300884956, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18664; Mature: 18533

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPCTEHVAATTRKFPEVDLILEKYDHQPARLTLILQAIQDEYRYLPMEVLSHVIEELDI
CCCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
PATKVFGVVSFYAHFTLEPRGKYVIRLCDGTACHAKRSIPILEALYAKLGLSSKKVTTPD
CHHHHHHHHHHHHHEEECCCCCEEEEEECCCCHHCCCCCHHHHHHHHHHCCCCCCCCCCH
MLFTVETVTCLGACGLAPVMLINEEVYGRVTPASAVALIDEIIAKEANA
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SPCTEHVAATTRKFPEVDLILEKYDHQPARLTLILQAIQDEYRYLPMEVLSHVIEELDI
CCHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
PATKVFGVVSFYAHFTLEPRGKYVIRLCDGTACHAKRSIPILEALYAKLGLSSKKVTTPD
CHHHHHHHHHHHHHEEECCCCCEEEEEECCCCHHCCCCCHHHHHHHHHHCCCCCCCCCCH
MLFTVETVTCLGACGLAPVMLINEEVYGRVTPASAVALIDEIIAKEANA
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]