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The map label for this gene is cirA [H]

Identifier: 118579807

GI number: 118579807

Start: 1473087

End: 1475195

Strand: Reverse

Name: cirA [H]

Synonym: Ppro_1383

Alternate gene names: 118579807

Gene position: 1475195-1473087 (Counterclockwise)

Preceding gene: 118579811

Following gene: 118579806

Centisome position: 36.81

GC content: 61.69

Gene sequence:

>2109_bases
ATGGCCATGCAAAAGCCCAGGAGAAACGCCGGAAACCGCATGCCTGCACCCACCCACCCCATAGCCGCGAAATCGCCTTT
ATCCATGGGGCACCCCCTGCTTTGCCAGGCTCTCCGCATGGCACGGACCATTCTGCTGTTCGGCCTGCTCTCCTGTTCAC
CGGTCCTTGTCTTTGATGACGGGGAGGAGCTCACCCAGCTTTCCCTGGAGGAACTGCTGCAGGTCAAGATCATGTCCGTC
ACCGGCAGTTCCCGCTACGAGCAGGAGGCCAGCGAGGCGCCGGCCAGGGTCAGCATCATCGACGCCGCCGCCATCCGAAA
ATACGGCTACCGCACCCTGTCCGAGGCGTTGCAGGGGGAGACCGGCATCAACATGACCTATGACCGGAATTACGCGTACA
TCGGCTACCGGGGATTTTCCATGCCGGGGGACTACAACACCCGGGTACTGGTGCTTCTGGACGGCATCAGGCTGAACGAC
GAGGTGTACCACCAGGCGCCGCTGGGAACGGACTTCCCCCTGGACATGGACCTGGTGGAGCGCATCGAGATCATCCGCGG
GCCGAGCAACTCGCTGTACGGCAACAACGCCTTCCTGCTGACGGTGAACGTCATCACCACCTCGGCCAAGAGAAACGGGG
TCAACGTCGCCTCTTCGGTGGACACCCGCACCAGGGTAAGCGGACGGATCACCGCCGAGGCAGATCCCCGGGGCAAGGAC
TGGTCCCTGCTGGTCTCCGGCACCCTCGACCACGCGCCGGGCAACGACCTGTATTTCAGCGCCTACGACGATCCGGCCAA
CAACAACGGCAGGAGCAGGGACTGCGACTACGAGGGGAACGGCAGCTTCTTCCTCAAGGCCGAGAAGGGCGACCTGACCC
TGCTGGGCGGTTTCTCCCGCCGCAGGAAGGGGGTGCCCACCGGCGCCTTTGACGTCGTTTTCAACGATGACGGCAACACT
TCCTGGGACGAGCGTTCCTTCGCCGACCTGAGCTACACGAGAGGAAACGGCTCGGGGGATTCCCTGAAGGCGCGCACCTA
CTACAACGGCTACTTCTATAAGGAACGCTACATCTATACCCCGGCCGACCAGACATTTTACGATTACACCAAAAGCGCCG
TGCTGGGGGGAGAGCTGGTGATCAGCAGGAAACTCCCCTTCGACAACCACCTGGTGGGGGGGATCGACTACCACTATGCC
CTGCTCAGGGACCAGCGCACAAAGACGAAGGCGGACGGCACCACCCTGAACCTGCACTCCCCCCAGCACAGCCTGGGAGT
TTTCCTGCAGAACGAGTGGCGCATTTCCCCCAACCTGCTGCTGGATGCGGGGGTACGCTATGACTACTTCTCCCCCTCCC
TGCACACCTTCAACCCCAAGGCGGCCCTGATCTACAAGATCACTGACGACCTGGTTGCCAAGTACCTGTTCGGCAGGTCA
TTTCGCGCCCCCAACGCTTACGAGACCGACTACAAGGATTCCGGCAGCAACATACACGACAACCCGGATCTGAAAGAGGA
GTCCATGCTCAGCCACGAGCTGGTGCTGGAGTACTACCACGGCCCGGGCCAGCGGCTCTCAATGACCTGGTTCCATTACT
CCATCAAGAACCTGATCAACCAGGCCGTGGGGAGCGACGGCACCATGCGCTTCGAGAATACGGACAGGGTCAGGATCACC
GGCTTCGAACTGGAGCGGGAGTGGAGTTGGGAGGCCTGGTCCGGCAGGCTGGGCTACAGCTATCAACGGGCGCGGGATGT
GGAGAACGACACAGGCCTGACCAACTCGCCTGAATCGTTGATCAAGGCGAAACTCTCCCGCGACTTCCTCAACCGCCGCC
TGACCCTGTCGGGAGAACTGCAGTACCTGTCCCAGGTGGAAACCCTGGTGGCCGGGGTCAAGGGGGGCGACTACACCCTG
CTGCACCTGACCGCCCTGGCCCGCAACCTGCTGGTCAAAAACCTGGACGCGACCATCTCGGTGCGCAACCTGCTTAACGA
GAGCTACACCAATCCCGGATCCAACGATCATGTGGAGACCAGCTATCCGGTGGCCCTGATCCCCCAGGATGGCCGCACGG
TCACCTTCAAGCTGGAGTACCGCTTCTAG

Upstream 100 bases:

>100_bases
TTGCATGGACTCACCCCCATACCTATGGTAAAGACTTTAACGTTACTCTGTTTTTCCCGATTATCCGCCACCATTCCCCG
GGAGTGCCGCTCGGGCAACC

Downstream 100 bases:

>100_bases
CTCCGCCTGCCGCCGCAAAGCGGCCCACACCCGCCTTGACGCCCCTCCGCTTCCGTAGTACTCTGCCGAACCCGTAAATA
GCAACCGTTCACGCAAAGCC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MAMQKPRRNAGNRMPAPTHPIAAKSPLSMGHPLLCQALRMARTILLFGLLSCSPVLVFDDGEELTQLSLEELLQVKIMSV
TGSSRYEQEASEAPARVSIIDAAAIRKYGYRTLSEALQGETGINMTYDRNYAYIGYRGFSMPGDYNTRVLVLLDGIRLND
EVYHQAPLGTDFPLDMDLVERIEIIRGPSNSLYGNNAFLLTVNVITTSAKRNGVNVASSVDTRTRVSGRITAEADPRGKD
WSLLVSGTLDHAPGNDLYFSAYDDPANNNGRSRDCDYEGNGSFFLKAEKGDLTLLGGFSRRRKGVPTGAFDVVFNDDGNT
SWDERSFADLSYTRGNGSGDSLKARTYYNGYFYKERYIYTPADQTFYDYTKSAVLGGELVISRKLPFDNHLVGGIDYHYA
LLRDQRTKTKADGTTLNLHSPQHSLGVFLQNEWRISPNLLLDAGVRYDYFSPSLHTFNPKAALIYKITDDLVAKYLFGRS
FRAPNAYETDYKDSGSNIHDNPDLKEESMLSHELVLEYYHGPGQRLSMTWFHYSIKNLINQAVGSDGTMRFENTDRVRIT
GFELEREWSWEAWSGRLGYSYQRARDVENDTGLTNSPESLIKAKLSRDFLNRRLTLSGELQYLSQVETLVAGVKGGDYTL
LHLTALARNLLVKNLDATISVRNLLNESYTNPGSNDHVETSYPVALIPQDGRTVTFKLEYRF

Sequences:

>Translated_702_residues
MAMQKPRRNAGNRMPAPTHPIAAKSPLSMGHPLLCQALRMARTILLFGLLSCSPVLVFDDGEELTQLSLEELLQVKIMSV
TGSSRYEQEASEAPARVSIIDAAAIRKYGYRTLSEALQGETGINMTYDRNYAYIGYRGFSMPGDYNTRVLVLLDGIRLND
EVYHQAPLGTDFPLDMDLVERIEIIRGPSNSLYGNNAFLLTVNVITTSAKRNGVNVASSVDTRTRVSGRITAEADPRGKD
WSLLVSGTLDHAPGNDLYFSAYDDPANNNGRSRDCDYEGNGSFFLKAEKGDLTLLGGFSRRRKGVPTGAFDVVFNDDGNT
SWDERSFADLSYTRGNGSGDSLKARTYYNGYFYKERYIYTPADQTFYDYTKSAVLGGELVISRKLPFDNHLVGGIDYHYA
LLRDQRTKTKADGTTLNLHSPQHSLGVFLQNEWRISPNLLLDAGVRYDYFSPSLHTFNPKAALIYKITDDLVAKYLFGRS
FRAPNAYETDYKDSGSNIHDNPDLKEESMLSHELVLEYYHGPGQRLSMTWFHYSIKNLINQAVGSDGTMRFENTDRVRIT
GFELEREWSWEAWSGRLGYSYQRARDVENDTGLTNSPESLIKAKLSRDFLNRRLTLSGELQYLSQVETLVAGVKGGDYTL
LHLTALARNLLVKNLDATISVRNLLNESYTNPGSNDHVETSYPVALIPQDGRTVTFKLEYRF
>Mature_701_residues
AMQKPRRNAGNRMPAPTHPIAAKSPLSMGHPLLCQALRMARTILLFGLLSCSPVLVFDDGEELTQLSLEELLQVKIMSVT
GSSRYEQEASEAPARVSIIDAAAIRKYGYRTLSEALQGETGINMTYDRNYAYIGYRGFSMPGDYNTRVLVLLDGIRLNDE
VYHQAPLGTDFPLDMDLVERIEIIRGPSNSLYGNNAFLLTVNVITTSAKRNGVNVASSVDTRTRVSGRITAEADPRGKDW
SLLVSGTLDHAPGNDLYFSAYDDPANNNGRSRDCDYEGNGSFFLKAEKGDLTLLGGFSRRRKGVPTGAFDVVFNDDGNTS
WDERSFADLSYTRGNGSGDSLKARTYYNGYFYKERYIYTPADQTFYDYTKSAVLGGELVISRKLPFDNHLVGGIDYHYAL
LRDQRTKTKADGTTLNLHSPQHSLGVFLQNEWRISPNLLLDAGVRYDYFSPSLHTFNPKAALIYKITDDLVAKYLFGRSF
RAPNAYETDYKDSGSNIHDNPDLKEESMLSHELVLEYYHGPGQRLSMTWFHYSIKNLINQAVGSDGTMRFENTDRVRITG
FELEREWSWEAWSGRLGYSYQRARDVENDTGLTNSPESLIKAKLSRDFLNRRLTLSGELQYLSQVETLVAGVKGGDYTLL
HLTALARNLLVKNLDATISVRNLLNESYTNPGSNDHVETSYPVALIPQDGRTVTFKLEYRF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=737, Percent_Identity=25.3731343283582, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78827; Mature: 78696

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMQKPRRNAGNRMPAPTHPIAAKSPLSMGHPLLCQALRMARTILLFGLLSCSPVLVFDD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GEELTQLSLEELLQVKIMSVTGSSRYEQEASEAPARVSIIDAAAIRKYGYRTLSEALQGE
CHHHHHHHHHHHHEEEEEEECCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCC
TGINMTYDRNYAYIGYRGFSMPGDYNTRVLVLLDGIRLNDEVYHQAPLGTDFPLDMDLVE
CCCEEEECCCEEEEEEECCCCCCCCCCEEEEEEECEECCCHHHCCCCCCCCCCCCHHHHH
RIEIIRGPSNSLYGNNAFLLTVNVITTSAKRNGVNVASSVDTRTRVSGRITAEADPRGKD
HHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEECCCCCCEEECEEEEECCCCCCCC
WSLLVSGTLDHAPGNDLYFSAYDDPANNNGRSRDCDYEGNGSFFLKAEKGDLTLLGGFSR
EEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCHH
RRKGVPTGAFDVVFNDDGNTSWDERSFADLSYTRGNGSGDSLKARTYYNGYFYKERYIYT
HCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCEEEEEEEEEC
PADQTFYDYTKSAVLGGELVISRKLPFDNHLVGGIDYHYALLRDQRTKTKADGTTLNLHS
CCCCHHHHHHHHHEECCEEEEEECCCCCCCEECCCCCEEHHHHCCCCCCCCCCCEEEECC
PQHSLGVFLQNEWRISPNLLLDAGVRYDYFSPSLHTFNPKAALIYKITDDLVAKYLFGRS
CCCCEEEEEECCEEECCCEEEECCCEEEECCCCCCCCCCCEEEEEEEHHHHHHHHHHCCC
FRAPNAYETDYKDSGSNIHDNPDLKEESMLSHELVLEYYHGPGQRLSMTWFHYSIKNLIN
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHH
QAVGSDGTMRFENTDRVRITGFELEREWSWEAWSGRLGYSYQRARDVENDTGLTNSPESL
HHHCCCCEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHH
IKAKLSRDFLNRRLTLSGELQYLSQVETLVAGVKGGDYTLLHLTALARNLLVKNLDATIS
HHHHHHHHHHHCEEEECCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCHHH
VRNLLNESYTNPGSNDHVETSYPVALIPQDGRTVTFKLEYRF
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECC
>Mature Secondary Structure 
AMQKPRRNAGNRMPAPTHPIAAKSPLSMGHPLLCQALRMARTILLFGLLSCSPVLVFDD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GEELTQLSLEELLQVKIMSVTGSSRYEQEASEAPARVSIIDAAAIRKYGYRTLSEALQGE
CHHHHHHHHHHHHEEEEEEECCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCC
TGINMTYDRNYAYIGYRGFSMPGDYNTRVLVLLDGIRLNDEVYHQAPLGTDFPLDMDLVE
CCCEEEECCCEEEEEEECCCCCCCCCCEEEEEEECEECCCHHHCCCCCCCCCCCCHHHHH
RIEIIRGPSNSLYGNNAFLLTVNVITTSAKRNGVNVASSVDTRTRVSGRITAEADPRGKD
HHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEECCCCCCEEECEEEEECCCCCCCC
WSLLVSGTLDHAPGNDLYFSAYDDPANNNGRSRDCDYEGNGSFFLKAEKGDLTLLGGFSR
EEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCHH
RRKGVPTGAFDVVFNDDGNTSWDERSFADLSYTRGNGSGDSLKARTYYNGYFYKERYIYT
HCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCEEEEEEEEEC
PADQTFYDYTKSAVLGGELVISRKLPFDNHLVGGIDYHYALLRDQRTKTKADGTTLNLHS
CCCCHHHHHHHHHEECCEEEEEECCCCCCCEECCCCCEEHHHHCCCCCCCCCCCEEEECC
PQHSLGVFLQNEWRISPNLLLDAGVRYDYFSPSLHTFNPKAALIYKITDDLVAKYLFGRS
CCCCEEEEEECCEEECCCEEEECCCEEEECCCCCCCCCCCEEEEEEEHHHHHHHHHHCCC
FRAPNAYETDYKDSGSNIHDNPDLKEESMLSHELVLEYYHGPGQRLSMTWFHYSIKNLIN
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHH
QAVGSDGTMRFENTDRVRITGFELEREWSWEAWSGRLGYSYQRARDVENDTGLTNSPESL
HHHCCCCEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHH
IKAKLSRDFLNRRLTLSGELQYLSQVETLVAGVKGGDYTLLHLTALARNLLVKNLDATIS
HHHHHHHHHHHCEEEECCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCHHH
VRNLLNESYTNPGSNDHVETSYPVALIPQDGRTVTFKLEYRF
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]