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The map label for this gene is pepB [H]

Identifier: 118579806

GI number: 118579806

Start: 1471039

End: 1472808

Strand: Reverse

Name: pepB [H]

Synonym: Ppro_1382

Alternate gene names: 118579806

Gene position: 1472808-1471039 (Counterclockwise)

Preceding gene: 118579807

Following gene: 118579802

Centisome position: 36.75

GC content: 62.94

Gene sequence:

>1770_bases
ATGACCACAGCCGACCTGACCTGGAACACCGCCCTGCTCTACCCCGCCCCCGATTCGGCCGAACTGGAGGCAGACCTGGG
CTCCTTCGACGCCCTGGCCGCCGACTTCCGGGAACGCTATTTCGAGAAGATCGCCCAGCTGCAACCCTCTTCCCTGCTGG
AGGCGGTGCGGGAATACGAGGCGCTGCAGGTGCGCATGGCAAAGCCGTTCTGCTATGCCCATCTGCTGTTCGCCGCCGAT
TCGTCCAACGAGACCACCCTCTCCCTCTCCCAGCGCTGCAGCGAGCTGGGCAGCCGCCTCTCCCAGCAGCTGCTCTTCTT
CGACCTGGAGCTGATGAACCTGGATGACGCCCCCTTCCAGGCGCTCTGTTCACTCCCCCAGGCGGCGCCCTACGTCCACT
TCCTGAACGGCATCCGTAAGTTCCGTCCCTACACCCTGAAGGAGAACGAGGAGCGGCTGCTTACCCGCAAGAACCTGACC
GGCGTCAGCGCCTTCACCCGGCTGTTCGACGAGCTCTCCGCCTCCCTGCGCTACTCCATGGAGCTGGATGGCCAGGTGCG
AGAGTTCACCGGCGAAGAGCTGCTCTCCCTTTTACACCACCACGACCCCGATGTGCGCTTCCGGGCCATGACCACCTTCC
TGGAGAAGCATGGCCAGAACGGCATCGTCTTTAACGCCGTTTTCAACAACATGGCCCTGGACCACGGCCAGGAGATGGAG
CTGCGCGGCTACAGTTCGCCGATCCAGCCCACCAACATCGGCAACGAGATCCCGGACGAGGCGGTGGAGCACCTGATGGC
GGTCACCGAGGCCAACTACGGCCTGGCCCAGGAGTACTTCCGCCTCAAGGCGGGGCTTTTGGGGATGGAAAAGATCCGCA
ACTGCGACATCTACGCCCCGCTTGCGGAGTCCAGAAAGAGCTACGAATTCGACGAGGCGCGGGACCTGGTGGTGGCCTCC
TACGGCGCCTACGACGCCGAATTCGGCCGTATCGTGGCCGATTTCTTCACGGAGCGACGGGTGGATGTCATGCCGCGCCC
CGGCAAGTCCGGTGGCGCCTTCGCCATGGGCATCTCCCCCCAGACGCCGCCATTCCTGCTGCTCAACTTCACCGGCACCC
TGCGCGACCTGGCCACCATCGCCCATGAGGCCGGTCACGGCCTGCACTTCGTCCTCTCCCAGAAACAGAACATGCTCAAC
TACCACGCCCCACTCCCCCTGGCGGAGACAGCCTCGGTGTTCGGGGAGATGCTGTTGACCCGCAGGCTGCTGGACAGCGA
GAGCGATCCGCTGCTGCGAAAATCGCTGCTCTGCGCCAAAATAGAGGACATCATCGCCACCACCTTCCGCCAGACCGTGC
TGACCCGTTTCGAACTGCGCCTGCACACCGAGCGCAGCAAGGGGCTGCTCACCAACGACCGTGTCTCCCGCATCTGGCTG
GAGGAGAACGAAAAGCTGTTCGGCAACGCGGTGGAGATGATCCCGGCCTACAGCTGGGGCTGGAGTTACATCAGCCACTT
CATCCACAGCCGCTTCTACTGCTACTCCTACACCTTTGCCGAACTGCTGGTGCTGGCCCTGTTCCAGAATTATTGCGAGA
AAGGGGAGAGCTTCAAGCCGGGCTATCGCTCGCTTCTGGAATCCGGTGGCGCCCTCTCCCCGACGGAGACGGCCCGACTG
GCAGGCATCGACATCACCGCCGGAGATTTCTGGCAGAAGGGGTATGACTTCCTGGGAGGGTTGATTCAGGAGCTGAAGGC
AGTTTTGTAA

Upstream 100 bases:

>100_bases
TGTTGTGCACCCATGTGATTTCTTTGCGTCTTCGCGCCTTAGCGTGAGATGATTCGCCGTTTTTTTTGGAATGTCCATGA
CCGGAGGAGAACCCTGACCA

Downstream 100 bases:

>100_bases
TTTTACACCTAGGGTGACACGAAAACGGGCAGCCTGCTATCAGGCTGCCCGTTTTCGGTTTGAAGAGTATATCCGGCTTT
TTCCTAGGCGAGCAGCGTCA

Product: pepF/M3 family oligoendopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MTTADLTWNTALLYPAPDSAELEADLGSFDALAADFRERYFEKIAQLQPSSLLEAVREYEALQVRMAKPFCYAHLLFAAD
SSNETTLSLSQRCSELGSRLSQQLLFFDLELMNLDDAPFQALCSLPQAAPYVHFLNGIRKFRPYTLKENEERLLTRKNLT
GVSAFTRLFDELSASLRYSMELDGQVREFTGEELLSLLHHHDPDVRFRAMTTFLEKHGQNGIVFNAVFNNMALDHGQEME
LRGYSSPIQPTNIGNEIPDEAVEHLMAVTEANYGLAQEYFRLKAGLLGMEKIRNCDIYAPLAESRKSYEFDEARDLVVAS
YGAYDAEFGRIVADFFTERRVDVMPRPGKSGGAFAMGISPQTPPFLLLNFTGTLRDLATIAHEAGHGLHFVLSQKQNMLN
YHAPLPLAETASVFGEMLLTRRLLDSESDPLLRKSLLCAKIEDIIATTFRQTVLTRFELRLHTERSKGLLTNDRVSRIWL
EENEKLFGNAVEMIPAYSWGWSYISHFIHSRFYCYSYTFAELLVLALFQNYCEKGESFKPGYRSLLESGGALSPTETARL
AGIDITAGDFWQKGYDFLGGLIQELKAVL

Sequences:

>Translated_589_residues
MTTADLTWNTALLYPAPDSAELEADLGSFDALAADFRERYFEKIAQLQPSSLLEAVREYEALQVRMAKPFCYAHLLFAAD
SSNETTLSLSQRCSELGSRLSQQLLFFDLELMNLDDAPFQALCSLPQAAPYVHFLNGIRKFRPYTLKENEERLLTRKNLT
GVSAFTRLFDELSASLRYSMELDGQVREFTGEELLSLLHHHDPDVRFRAMTTFLEKHGQNGIVFNAVFNNMALDHGQEME
LRGYSSPIQPTNIGNEIPDEAVEHLMAVTEANYGLAQEYFRLKAGLLGMEKIRNCDIYAPLAESRKSYEFDEARDLVVAS
YGAYDAEFGRIVADFFTERRVDVMPRPGKSGGAFAMGISPQTPPFLLLNFTGTLRDLATIAHEAGHGLHFVLSQKQNMLN
YHAPLPLAETASVFGEMLLTRRLLDSESDPLLRKSLLCAKIEDIIATTFRQTVLTRFELRLHTERSKGLLTNDRVSRIWL
EENEKLFGNAVEMIPAYSWGWSYISHFIHSRFYCYSYTFAELLVLALFQNYCEKGESFKPGYRSLLESGGALSPTETARL
AGIDITAGDFWQKGYDFLGGLIQELKAVL
>Mature_588_residues
TTADLTWNTALLYPAPDSAELEADLGSFDALAADFRERYFEKIAQLQPSSLLEAVREYEALQVRMAKPFCYAHLLFAADS
SNETTLSLSQRCSELGSRLSQQLLFFDLELMNLDDAPFQALCSLPQAAPYVHFLNGIRKFRPYTLKENEERLLTRKNLTG
VSAFTRLFDELSASLRYSMELDGQVREFTGEELLSLLHHHDPDVRFRAMTTFLEKHGQNGIVFNAVFNNMALDHGQEMEL
RGYSSPIQPTNIGNEIPDEAVEHLMAVTEANYGLAQEYFRLKAGLLGMEKIRNCDIYAPLAESRKSYEFDEARDLVVASY
GAYDAEFGRIVADFFTERRVDVMPRPGKSGGAFAMGISPQTPPFLLLNFTGTLRDLATIAHEAGHGLHFVLSQKQNMLNY
HAPLPLAETASVFGEMLLTRRLLDSESDPLLRKSLLCAKIEDIIATTFRQTVLTRFELRLHTERSKGLLTNDRVSRIWLE
ENEKLFGNAVEMIPAYSWGWSYISHFIHSRFYCYSYTFAELLVLALFQNYCEKGESFKPGYRSLLESGGALSPTETARLA
GIDITAGDFWQKGYDFLGGLIQELKAVL

Specific function: Has oligopeptidase activity and degrades a variety of small bioactive peptides, including bradykinin, neurotensin, and peptide fragments of substance P and adrenocorticotropin. Also hydrolyzes the synthetic collagen-like substrate N-(3-[2- furyl]acryloyl)

COG id: COG1164

COG function: function code E; Oligoendopeptidase F

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567
- InterPro:   IPR004438
- InterPro:   IPR013647 [H]

Pfam domain/function: PF01432 Peptidase_M3; PF08439 Peptidase_M3_N [H]

EC number: NA

Molecular weight: Translated: 66563; Mature: 66432

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTADLTWNTALLYPAPDSAELEADLGSFDALAADFRERYFEKIAQLQPSSLLEAVREYE
CCCCCCEECEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ALQVRMAKPFCYAHLLFAADSSNETTLSLSQRCSELGSRLSQQLLFFDLELMNLDDAPFQ
HHHHHHCCCHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHH
ALCSLPQAAPYVHFLNGIRKFRPYTLKENEERLLTRKNLTGVSAFTRLFDELSASLRYSM
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEE
ELDGQVREFTGEELLSLLHHHDPDVRFRAMTTFLEKHGQNGIVFNAVFNNMALDHGQEME
ECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCEE
LRGYSSPIQPTNIGNEIPDEAVEHLMAVTEANYGLAQEYFRLKAGLLGMEKIRNCDIYAP
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECC
LAESRKSYEFDEARDLVVASYGAYDAEFGRIVADFFTERRVDVMPRPGKSGGAFAMGISP
HHHCCCCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCC
QTPPFLLLNFTGTLRDLATIAHEAGHGLHFVLSQKQNMLNYHAPLPLAETASVFGEMLLT
CCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RRLLDSESDPLLRKSLLCAKIEDIIATTFRQTVLTRFELRLHTERSKGLLTNDRVSRIWL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHEEEC
EENEKLFGNAVEMIPAYSWGWSYISHFIHSRFYCYSYTFAELLVLALFQNYCEKGESFKP
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
GYRSLLESGGALSPTETARLAGIDITAGDFWQKGYDFLGGLIQELKAVL
HHHHHHHCCCCCCCCCHHHEECEECCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TTADLTWNTALLYPAPDSAELEADLGSFDALAADFRERYFEKIAQLQPSSLLEAVREYE
CCCCCEECEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ALQVRMAKPFCYAHLLFAADSSNETTLSLSQRCSELGSRLSQQLLFFDLELMNLDDAPFQ
HHHHHHCCCHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHH
ALCSLPQAAPYVHFLNGIRKFRPYTLKENEERLLTRKNLTGVSAFTRLFDELSASLRYSM
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEE
ELDGQVREFTGEELLSLLHHHDPDVRFRAMTTFLEKHGQNGIVFNAVFNNMALDHGQEME
ECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCEE
LRGYSSPIQPTNIGNEIPDEAVEHLMAVTEANYGLAQEYFRLKAGLLGMEKIRNCDIYAP
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECC
LAESRKSYEFDEARDLVVASYGAYDAEFGRIVADFFTERRVDVMPRPGKSGGAFAMGISP
HHHCCCCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCC
QTPPFLLLNFTGTLRDLATIAHEAGHGLHFVLSQKQNMLNYHAPLPLAETASVFGEMLLT
CCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RRLLDSESDPLLRKSLLCAKIEDIIATTFRQTVLTRFELRLHTERSKGLLTNDRVSRIWL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHEEEC
EENEKLFGNAVEMIPAYSWGWSYISHFIHSRFYCYSYTFAELLVLALFQNYCEKGESFKP
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
GYRSLLESGGALSPTETARLAGIDITAGDFWQKGYDFLGGLIQELKAVL
HHHHHHHCCCCCCCCCHHHEECEECCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757883; 12354221 [H]