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The map label for this gene is intA [H]

Identifier: 118579795

GI number: 118579795

Start: 1453301

End: 1454662

Strand: Reverse

Name: intA [H]

Synonym: Ppro_1371

Alternate gene names: 118579795

Gene position: 1454662-1453301 (Counterclockwise)

Preceding gene: 118579796

Following gene: 118579794

Centisome position: 36.29

GC content: 48.02

Gene sequence:

>1362_bases
ATGAAATTCACGGATACCGGAATCAGAAACCTGAAACCAAAAGAGAAGATGTATCAGGTGCGTGAGGGTGACGGCTTTGG
CGTCCGCGTGCTTCCATCCGGGCTTCGGATTTTTGTTTTTATTTACACGATTGCGGGAAAGCGCCGCCAGATGAATCTCG
GGGATTATCCGGCTGTCAGTTTATCAGAGGCACGTGAACGGGCGGCAGATGCCAGAAAGGTCTTGAGCCGTGAAAGGACC
GATCCTCAAGAGCACGGTTTTTCGTGGCACTACAGCCCAGAACGCGAGCGGCGAGAAATGGCAGCAAAGGAAAAAGAAGA
ACTGGAAAACCCTACCGTAAAGCAGCTCATTACGAGGTACATTGAGCGGTATGCCATGAAGAACAAGAAGTCGTGGCAAG
AAGACAAGCGGATACTTGAAAAGGATGTACTGCCATTATGGGGCGACAGAAAAGCAAAAGACGTTATTCGTCGTGACGTA
ATTCAGTTGCTGGACGGTATGCAGGGGCGCGGTGATGGCATCATCACCAATACTTTTAAAATCATCCGGCGCATGTTCCG
GTACGGCGTAAAGCAGGAACTGATTCCGACAACGCCCTGTTATGGGTTCGAGAAAGGCGATGAACTGCCAACTACCAAAT
CGAAGGAAAGGACACTGACAGAGACTGAAATCAAGGCATTTTGGGGAGGAATTGACCGGTGTATGATATCGGAAGATGTT
CGACGGATACTAAAACTGACCCTGTTAACTGGTCAGAGACCGGGCGAGGTCGCTTCAATGCACTCATCTGAGATCAGCGG
TCGCTGGTGGGAATTTTCTCCCAAAGAAACCAAGATCACCAAGGAAGTACCGAGAAAGCAACGCATATACCTGACTGATA
TGACACTCTCGCTGATCCGGGAGAAGGAAGGATATATTTTCCCCTCCCCGAAGATCCGGACCAATGTCAACGAACAGCCA
ATTGACACGCCTATCACGGAAAGGGCCGTTGCTTATGCTTTGCGGCGCAACCTGCTTACGCACACGGTAAAACCAAAACC
CGCAACTTGGAAAAAATCCAGCCACCAGTCTAAAGACAAGAAAAAATTTATCATCCCGGATGACAAGAAACTTGATATCG
AAAAGTTTTGCCCTCATGACTTGCGCCGTACGTGTGCAACGATTCTTTCAGAAATTGGCTTTTCAGACGAAATTGTTGAT
GCAGTGCTTGCCCATCTCAAGAAAGGCGAGATCAAGACATACAACAAGAATAAATACGACAAAGAGCGGCAGAAAGCCCT
TGAGGCATGGGAAAGAAAATTGAAATCTATCATCACCGGTCAGAAAGATAATGTGGTGCCATTGACACATAAAGCCGCTT
GA

Upstream 100 bases:

>100_bases
CTATTTCATAGTGTTTCATTGACAACCACATATCAAGAGGTTACACAAGAGGTTACACGAGAAAAGTGTAACCTCTTTGC
CAGCTCCCTGGGAGGATGAT

Downstream 100 bases:

>100_bases
AACAGGGAAACTAGTACAAGCTGATTACCTCTCACCCAATCCTCTTCAGATAAGTACACGCCTCAATTGGTTGGAACCAG
GAGCCTGTGGTAATTATTAC

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKFTDTGIRNLKPKEKMYQVREGDGFGVRVLPSGLRIFVFIYTIAGKRRQMNLGDYPAVSLSEARERAADARKVLSRERT
DPQEHGFSWHYSPERERREMAAKEKEELENPTVKQLITRYIERYAMKNKKSWQEDKRILEKDVLPLWGDRKAKDVIRRDV
IQLLDGMQGRGDGIITNTFKIIRRMFRYGVKQELIPTTPCYGFEKGDELPTTKSKERTLTETEIKAFWGGIDRCMISEDV
RRILKLTLLTGQRPGEVASMHSSEISGRWWEFSPKETKITKEVPRKQRIYLTDMTLSLIREKEGYIFPSPKIRTNVNEQP
IDTPITERAVAYALRRNLLTHTVKPKPATWKKSSHQSKDKKKFIIPDDKKLDIEKFCPHDLRRTCATILSEIGFSDEIVD
AVLAHLKKGEIKTYNKNKYDKERQKALEAWERKLKSIITGQKDNVVPLTHKAA

Sequences:

>Translated_453_residues
MKFTDTGIRNLKPKEKMYQVREGDGFGVRVLPSGLRIFVFIYTIAGKRRQMNLGDYPAVSLSEARERAADARKVLSRERT
DPQEHGFSWHYSPERERREMAAKEKEELENPTVKQLITRYIERYAMKNKKSWQEDKRILEKDVLPLWGDRKAKDVIRRDV
IQLLDGMQGRGDGIITNTFKIIRRMFRYGVKQELIPTTPCYGFEKGDELPTTKSKERTLTETEIKAFWGGIDRCMISEDV
RRILKLTLLTGQRPGEVASMHSSEISGRWWEFSPKETKITKEVPRKQRIYLTDMTLSLIREKEGYIFPSPKIRTNVNEQP
IDTPITERAVAYALRRNLLTHTVKPKPATWKKSSHQSKDKKKFIIPDDKKLDIEKFCPHDLRRTCATILSEIGFSDEIVD
AVLAHLKKGEIKTYNKNKYDKERQKALEAWERKLKSIITGQKDNVVPLTHKAA
>Mature_453_residues
MKFTDTGIRNLKPKEKMYQVREGDGFGVRVLPSGLRIFVFIYTIAGKRRQMNLGDYPAVSLSEARERAADARKVLSRERT
DPQEHGFSWHYSPERERREMAAKEKEELENPTVKQLITRYIERYAMKNKKSWQEDKRILEKDVLPLWGDRKAKDVIRRDV
IQLLDGMQGRGDGIITNTFKIIRRMFRYGVKQELIPTTPCYGFEKGDELPTTKSKERTLTETEIKAFWGGIDRCMISEDV
RRILKLTLLTGQRPGEVASMHSSEISGRWWEFSPKETKITKEVPRKQRIYLTDMTLSLIREKEGYIFPSPKIRTNVNEQP
IDTPITERAVAYALRRNLLTHTVKPKPATWKKSSHQSKDKKKFIIPDDKKLDIEKFCPHDLRRTCATILSEIGFSDEIVD
AVLAHLKKGEIKTYNKNKYDKERQKALEAWERKLKSIITGQKDNVVPLTHKAA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=474, Percent_Identity=25.3164556962025, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI145693166, Length=459, Percent_Identity=22.2222222222222, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 52768; Mature: 52768

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTDTGIRNLKPKEKMYQVREGDGFGVRVLPSGLRIFVFIYTIAGKRRQMNLGDYPAVS
CCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCEEHHHHHHHCCCCEECCCCCCCCCC
LSEARERAADARKVLSRERTDPQEHGFSWHYSPERERREMAAKEKEELENPTVKQLITRY
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
IERYAMKNKKSWQEDKRILEKDVLPLWGDRKAKDVIRRDVIQLLDGMQGRGDGIITNTFK
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
IIRRMFRYGVKQELIPTTPCYGFEKGDELPTTKSKERTLTETEIKAFWGGIDRCMISEDV
HHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRILKLTLLTGQRPGEVASMHSSEISGRWWEFSPKETKITKEVPRKQRIYLTDMTLSLIR
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEEHHHHHHHH
EKEGYIFPSPKIRTNVNEQPIDTPITERAVAYALRRNLLTHTVKPKPATWKKSSHQSKDK
HCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KKFIIPDDKKLDIEKFCPHDLRRTCATILSEIGFSDEIVDAVLAHLKKGEIKTYNKNKYD
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCH
KERQKALEAWERKLKSIITGQKDNVVPLTHKAA
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCC
>Mature Secondary Structure
MKFTDTGIRNLKPKEKMYQVREGDGFGVRVLPSGLRIFVFIYTIAGKRRQMNLGDYPAVS
CCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCEEHHHHHHHCCCCEECCCCCCCCCC
LSEARERAADARKVLSRERTDPQEHGFSWHYSPERERREMAAKEKEELENPTVKQLITRY
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
IERYAMKNKKSWQEDKRILEKDVLPLWGDRKAKDVIRRDVIQLLDGMQGRGDGIITNTFK
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
IIRRMFRYGVKQELIPTTPCYGFEKGDELPTTKSKERTLTETEIKAFWGGIDRCMISEDV
HHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRILKLTLLTGQRPGEVASMHSSEISGRWWEFSPKETKITKEVPRKQRIYLTDMTLSLIR
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCEEEEEHHHHHHHH
EKEGYIFPSPKIRTNVNEQPIDTPITERAVAYALRRNLLTHTVKPKPATWKKSSHQSKDK
HCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KKFIIPDDKKLDIEKFCPHDLRRTCATILSEIGFSDEIVDAVLAHLKKGEIKTYNKNKYD
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCH
KERQKALEAWERKLKSIITGQKDNVVPLTHKAA
HHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]