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The map label for this gene is pgi [H]

Identifier: 118579796

GI number: 118579796

Start: 1455042

End: 1456631

Strand: Reverse

Name: pgi [H]

Synonym: Ppro_1372

Alternate gene names: 118579796

Gene position: 1456631-1455042 (Counterclockwise)

Preceding gene: 118579797

Following gene: 118579795

Centisome position: 36.34

GC content: 65.79

Gene sequence:

>1590_bases
ATGACCCCAACCAGCCTGTGGGAGCGCTACTGCCAATCCCTCTGTCTCTGCCCCGAAATCGGCCTGTCCCTGGATATCAG
CCGCATGAACCACGACGATGGTTTCCTGGAGCGCATGGAACCTGCCATGCAGAAGGCCTACGCCGAAATGGCGGCGCTGG
AGGGGGGGGCACAAGCCAACCAGGACGAGGGGCGCATGGTCGGGCACTACTGGCTGCGCACCCCCTCCCTGGCGCCCCGG
GACGATATCCGGCGCGAGATCGAGGAGACCCTGGAACGGATTCTCCTCTTCTGCCATCGCATCCACTCCGGCGGCATAAC
CAGCCAGAATAGCGGGAGTTTCACCCGCATGCTGATCATCGGCATCGGCGGCTCGGCCCTGGGGCCCCAGTTCGTGGCCG
ACGCCCTCTCCTCCCCCAACGATCCGCTCAAACCCCATTTCCTGGACAACACCGACCCTGACGGCATGGACCGGGTCATG
GCCGAGATTGGTGACGACCTGGCCAGAACCCTGGTCATCGTCATCTCCAAGAGCGGCTCCACCAAGGAGACCCGCAACGG
CATGCTGGAAGCCATGGCCGCCTACCGGCAACGGGGGCTGGACTTCGCCCGCCACGCCCTGGCCATAACCGGTAAAGACA
GCCAGCTGGACCGTCTGGCCCGCGATCAGGGGTGGCTGGAGCGCTTCCCCATGTGGGATTGGGTCGGTGGACGCACCTCG
GTGACCTCGGCGGTGGGGCTGCTGCCGGCCGCCCTGCAGGGGATCGACATCAGCGCCCTCTTGCAGGGGGCCGCGGCCTG
CGACGCCCTCACCCGCCGGACGGAGACAAGTTCCAACCCGGCGGCCCTGATGGCGCTGATGTGGCATTACGCCGGCAACG
GCCGCGGGGAGCGGGACCTGGTCATGCTCCCCTACCGTGACCGGCTGCTGCTCTTCTCCCGCTACCTGCAGCAACTCTTG
ATGGAGTCCCTAGGCAAGGAGCTGGACCGGGAGGGAAGGATCGTCAACCAGGGGATCGCCGTCTACGGCAACAAGGGATC
CACCGACCAGCACGCCTATGTGCAGCAGCTGCGCGACGGCCTGGACAACTTCTTCGTCACCTTCATCCAGGTGCTGAGAG
ACCGGGACGCTTCATCCCTGGAGGTGGAAGAGGGGGTCACCAGCGGCGACTTCCTGTTCGGCTTCCTGCAGGGCACCCGC
ACGGCGCTGCACGACAAGGGGCGCCAGTCCCTGACCATCAGCGTGGAGCGCATCGACCCGTTCACCATCGGCGCCCTGAT
CGCCCTGTTCGAGCGCTGCGTAGGGCTATACGCCAGCCTGATCAACATCAACGCCTACCATCAGCCGGGGGTTGAAGCGG
GCAAGAAGGCCGCCGGAGCGGTCATCGAGCTGCAGAGAGAGCTGCGGGATTATCTGACGGCACAGGGACGCGCCATGACC
GCGGGAGAGATCGCAGCGGGATTGGGCAGGTCTGAGCGGACCGAGGAGATCTTCGCCATCCTGCGCCACCTGGCGGCCAA
CCCGGAGCGGGGCGTGGTGGTTGAAAGAACGAGCGCCGTGGAAGAGTGGCGCTTTTCCATGGGGACCTGA

Upstream 100 bases:

>100_bases
CGGCGCAACCGGAACCGGACCGAAAAAACCGCCCCGCCAGGTTGACAGACTCCCTGTTGTATGAAACGGTTATACAACAT
CACTCACCAAGGAGCCTGTC

Downstream 100 bases:

>100_bases
GCCGGTTGTGACCGGCCAGACAAGGACTGCCTGAAGAAGGGGAGGCACGAAACACGCATCACCCTGGCGCGGCAGGCTCC
GCACCAAGTTCAAAAAACAA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MTPTSLWERYCQSLCLCPEIGLSLDISRMNHDDGFLERMEPAMQKAYAEMAALEGGAQANQDEGRMVGHYWLRTPSLAPR
DDIRREIEETLERILLFCHRIHSGGITSQNSGSFTRMLIIGIGGSALGPQFVADALSSPNDPLKPHFLDNTDPDGMDRVM
AEIGDDLARTLVIVISKSGSTKETRNGMLEAMAAYRQRGLDFARHALAITGKDSQLDRLARDQGWLERFPMWDWVGGRTS
VTSAVGLLPAALQGIDISALLQGAAACDALTRRTETSSNPAALMALMWHYAGNGRGERDLVMLPYRDRLLLFSRYLQQLL
MESLGKELDREGRIVNQGIAVYGNKGSTDQHAYVQQLRDGLDNFFVTFIQVLRDRDASSLEVEEGVTSGDFLFGFLQGTR
TALHDKGRQSLTISVERIDPFTIGALIALFERCVGLYASLININAYHQPGVEAGKKAAGAVIELQRELRDYLTAQGRAMT
AGEIAAGLGRSERTEEIFAILRHLAANPERGVVVERTSAVEEWRFSMGT

Sequences:

>Translated_529_residues
MTPTSLWERYCQSLCLCPEIGLSLDISRMNHDDGFLERMEPAMQKAYAEMAALEGGAQANQDEGRMVGHYWLRTPSLAPR
DDIRREIEETLERILLFCHRIHSGGITSQNSGSFTRMLIIGIGGSALGPQFVADALSSPNDPLKPHFLDNTDPDGMDRVM
AEIGDDLARTLVIVISKSGSTKETRNGMLEAMAAYRQRGLDFARHALAITGKDSQLDRLARDQGWLERFPMWDWVGGRTS
VTSAVGLLPAALQGIDISALLQGAAACDALTRRTETSSNPAALMALMWHYAGNGRGERDLVMLPYRDRLLLFSRYLQQLL
MESLGKELDREGRIVNQGIAVYGNKGSTDQHAYVQQLRDGLDNFFVTFIQVLRDRDASSLEVEEGVTSGDFLFGFLQGTR
TALHDKGRQSLTISVERIDPFTIGALIALFERCVGLYASLININAYHQPGVEAGKKAAGAVIELQRELRDYLTAQGRAMT
AGEIAAGLGRSERTEEIFAILRHLAANPERGVVVERTSAVEEWRFSMGT
>Mature_528_residues
TPTSLWERYCQSLCLCPEIGLSLDISRMNHDDGFLERMEPAMQKAYAEMAALEGGAQANQDEGRMVGHYWLRTPSLAPRD
DIRREIEETLERILLFCHRIHSGGITSQNSGSFTRMLIIGIGGSALGPQFVADALSSPNDPLKPHFLDNTDPDGMDRVMA
EIGDDLARTLVIVISKSGSTKETRNGMLEAMAAYRQRGLDFARHALAITGKDSQLDRLARDQGWLERFPMWDWVGGRTSV
TSAVGLLPAALQGIDISALLQGAAACDALTRRTETSSNPAALMALMWHYAGNGRGERDLVMLPYRDRLLLFSRYLQQLLM
ESLGKELDREGRIVNQGIAVYGNKGSTDQHAYVQQLRDGLDNFFVTFIQVLRDRDASSLEVEEGVTSGDFLFGFLQGTRT
ALHDKGRQSLTISVERIDPFTIGALIALFERCVGLYASLININAYHQPGVEAGKKAAGAVIELQRELRDYLTAQGRAMTA
GEIAAGLGRSERTEEIFAILRHLAANPERGVVVERTSAVEEWRFSMGT

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=449, Percent_Identity=29.1759465478842, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI296080693, Length=449, Percent_Identity=26.7260579064588, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1790457, Length=461, Percent_Identity=29.5010845986985, Blast_Score=167, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71996703, Length=517, Percent_Identity=28.2398452611219, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71996708, Length=517, Percent_Identity=28.2398452611219, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6319673, Length=448, Percent_Identity=27.9017857142857, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24651916, Length=479, Percent_Identity=28.39248434238, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24651914, Length=479, Percent_Identity=28.39248434238, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI17737445, Length=479, Percent_Identity=28.39248434238, Blast_Score=156, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 58414; Mature: 58283

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTSLWERYCQSLCLCPEIGLSLDISRMNHDDGFLERMEPAMQKAYAEMAALEGGAQAN
CCCHHHHHHHHHHHCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QDEGRMVGHYWLRTPSLAPRDDIRREIEETLERILLFCHRIHSGGITSQNSGSFTRMLII
CCCCCEEEHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
GIGGSALGPQFVADALSSPNDPLKPHFLDNTDPDGMDRVMAEIGDDLARTLVIVISKSGS
ECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCC
TKETRNGMLEAMAAYRQRGLDFARHALAITGKDSQLDRLARDQGWLERFPMWDWVGGRTS
CHHHHHHHHHHHHHHHHHCHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHH
VTSAVGLLPAALQGIDISALLQGAAACDALTRRTETSSNPAALMALMWHYAGNGRGERDL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCE
VMLPYRDRLLLFSRYLQQLLMESLGKELDREGRIVNQGIAVYGNKGSTDQHAYVQQLRDG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCHHHHHHHHHHHH
LDNFFVTFIQVLRDRDASSLEVEEGVTSGDFLFGFLQGTRTALHDKGRQSLTISVERIDP
HHHHHHHHHHHHHCCCCCCEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
FTIGALIALFERCVGLYASLININAYHQPGVEAGKKAAGAVIELQRELRDYLTAQGRAMT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AGEIAAGLGRSERTEEIFAILRHLAANPERGVVVERTSAVEEWRFSMGT
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPTSLWERYCQSLCLCPEIGLSLDISRMNHDDGFLERMEPAMQKAYAEMAALEGGAQAN
CCHHHHHHHHHHHCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QDEGRMVGHYWLRTPSLAPRDDIRREIEETLERILLFCHRIHSGGITSQNSGSFTRMLII
CCCCCEEEHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
GIGGSALGPQFVADALSSPNDPLKPHFLDNTDPDGMDRVMAEIGDDLARTLVIVISKSGS
ECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCC
TKETRNGMLEAMAAYRQRGLDFARHALAITGKDSQLDRLARDQGWLERFPMWDWVGGRTS
CHHHHHHHHHHHHHHHHHCHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHH
VTSAVGLLPAALQGIDISALLQGAAACDALTRRTETSSNPAALMALMWHYAGNGRGERDL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCE
VMLPYRDRLLLFSRYLQQLLMESLGKELDREGRIVNQGIAVYGNKGSTDQHAYVQQLRDG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCHHHHHHHHHHHH
LDNFFVTFIQVLRDRDASSLEVEEGVTSGDFLFGFLQGTRTALHDKGRQSLTISVERIDP
HHHHHHHHHHHHHCCCCCCEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
FTIGALIALFERCVGLYASLININAYHQPGVEAGKKAAGAVIELQRELRDYLTAQGRAMT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AGEIAAGLGRSERTEEIFAILRHLAANPERGVVVERTSAVEEWRFSMGT
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA