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The map label for this gene is cbiC [H]

Identifier: 118579726

GI number: 118579726

Start: 1367281

End: 1367916

Strand: Reverse

Name: cbiC [H]

Synonym: Ppro_1298

Alternate gene names: 118579726

Gene position: 1367916-1367281 (Counterclockwise)

Preceding gene: 118579727

Following gene: 118579725

Centisome position: 34.13

GC content: 64.94

Gene sequence:

>636_bases
ATGGATTCCCTGGCGATGAAACCGGAAGAGATCGAGGCGGAGTCCTTCCGCATCATCGACGCCGAGGCCGGCCGGCACGA
CTGGCCCCCGGCAGAATGGCAGGTCGTGCGCCGGGCAGTACATACCAGCGCGGATTTTGAATACGTGAGGAGCATGGTCT
TTTCCCAGGGGGCCGTGGAACAGGCCGTGGCGGCGCTCAAGAGCGGCTATGGCATCGTCACCGACACAAACATGGCCCTT
TCCGGCATCAGCAAGGTCCGCCTGGCGCGCTTCGGCACCAGGGTCAACTGCCACGTGGCCGATCCCGACGTCATCGAAAT
AGCCAAACAGGAGGGGATCACCCGCTCCATCGCGGCCATGCGCAAGGCGGTGGGCGACCCCGTGAACCGCATCTTCGTCA
TCGGCAACGCCCCCACGGCACTGTTCGAACTGCTGCGCCTGACCGACGAGGGCACGGCCAAACCGGCGCTGATCATCGGG
CTTCCGGTCGGCTTCGTGGGTGCCGAGGAGAGCAAGAACGCCCTGGCGGCAAGTGGCCAGGCGATCCCTTTCATCACCAA
CATTGGGCGCAAAGGAGGCTCCAACGTCGCCGCGGCTGTGGTGAACGCCCTGGCGATCCTGGCCGGGCAATGCTGA

Upstream 100 bases:

>100_bases
TGGTCATGGAAATGGGCGGCCACCTGGGTGCGCACCCCAAGCTGGCCGAGATCGAAAACGAACGCATCGGCGAGGCGCTG
GACAGACTGGGGTGGCGCTG

Downstream 100 bases:

>100_bases
CGCACTAGCGTTGCTCGGGAAAATTGACACACCCGGAAAGAGCGTTCGCATCTCACCCAAAGGCACGAAGCGCACGAAGA
GTAACCGCACGGCCGTAAGA

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MDSLAMKPEEIEAESFRIIDAEAGRHDWPPAEWQVVRRAVHTSADFEYVRSMVFSQGAVEQAVAALKSGYGIVTDTNMAL
SGISKVRLARFGTRVNCHVADPDVIEIAKQEGITRSIAAMRKAVGDPVNRIFVIGNAPTALFELLRLTDEGTAKPALIIG
LPVGFVGAEESKNALAASGQAIPFITNIGRKGGSNVAAAVVNALAILAGQC

Sequences:

>Translated_211_residues
MDSLAMKPEEIEAESFRIIDAEAGRHDWPPAEWQVVRRAVHTSADFEYVRSMVFSQGAVEQAVAALKSGYGIVTDTNMAL
SGISKVRLARFGTRVNCHVADPDVIEIAKQEGITRSIAAMRKAVGDPVNRIFVIGNAPTALFELLRLTDEGTAKPALIIG
LPVGFVGAEESKNALAASGQAIPFITNIGRKGGSNVAAAVVNALAILAGQC
>Mature_211_residues
MDSLAMKPEEIEAESFRIIDAEAGRHDWPPAEWQVVRRAVHTSADFEYVRSMVFSQGAVEQAVAALKSGYGIVTDTNMAL
SGISKVRLARFGTRVNCHVADPDVIEIAKQEGITRSIAAMRKAVGDPVNRIFVIGNAPTALFELLRLTDEGTAKPALIIG
LPVGFVGAEESKNALAASGQAIPFITNIGRKGGSNVAAAVVNALAILAGQC

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 22328; Mature: 22328

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLAMKPEEIEAESFRIIDAEAGRHDWPPAEWQVVRRAVHTSADFEYVRSMVFSQGAVE
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHH
QAVAALKSGYGIVTDTNMALSGISKVRLARFGTRVNCHVADPDVIEIAKQEGITRSIAAM
HHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCHHHHHHHH
RKAVGDPVNRIFVIGNAPTALFELLRLTDEGTAKPALIIGLPVGFVGAEESKNALAASGQ
HHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCC
AIPFITNIGRKGGSNVAAAVVNALAILAGQC
CCHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSLAMKPEEIEAESFRIIDAEAGRHDWPPAEWQVVRRAVHTSADFEYVRSMVFSQGAVE
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHH
QAVAALKSGYGIVTDTNMALSGISKVRLARFGTRVNCHVADPDVIEIAKQEGITRSIAAM
HHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCHHHHHHHH
RKAVGDPVNRIFVIGNAPTALFELLRLTDEGTAKPALIIGLPVGFVGAEESKNALAASGQ
HHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCC
AIPFITNIGRKGGSNVAAAVVNALAILAGQC
CCHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]