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The map label for this gene is purQ [H]

Identifier: 118579583

GI number: 118579583

Start: 1200743

End: 1201570

Strand: Direct

Name: purQ [H]

Synonym: Ppro_1152

Alternate gene names: 118579583

Gene position: 1200743-1201570 (Clockwise)

Preceding gene: 118579582

Following gene: 118579584

Centisome position: 29.96

GC content: 61.71

Gene sequence:

>828_bases
ATGCGGAAAACACGCGCGATCGTCATCACCGGAAACGGCACCAACTGCGAGATGGAGGCGGCCCACGCCTGCCGTCTGGG
GGGCTTTGACGAGGCGGTCATCGCCCACATCGCCGAGATCCTCTCCGGCGAAATCAGGCTGGACGATTTTCACTTCCTCA
ACCTGACCGGCGGCTTTCTGGATGGAGATGACCTGGGGAGCGCCAAGGCCCAGGCCAACCGCCTGCGTCACGCCAGCGTG
GCCGGTACGGACGAGAAGCTGGTGGAACAGTTCCTCCGCTTCATTCGTGACGGCAAGCTGATCCTGGGGGTCTGTAACGG
CTTCCAGCTGATGGTCAAGATGGGGGTCCTGCCCGGATTTGACAACGACTACCTGACCCAGACGGTGACCCTGACCCACA
ACGACTGCGGTCGATTCCAGGACCGCTGGACCTATCTGAAGGTGGATTCGGAATCCCCCTGCGTCTTCACCAGCGGGATC
GAGAGCGGCATCTACCTCCCCATGCGCCACGGCGAGGGGAAGTTCGTCTGCGATTCGCCCCAGACCCTGGAGCGGATTGA
AGGGGAACACCTGGCGGTTTTCAAATATTCGGATCCCGACTTCGTCCGGCCGACCATGGAGTTTCCCCATAACCCCAACG
GTTCCCAGAATGCCATCGCCGGTATCTGCGATGCCAGCGGCCGCCTCATGGGGCTGATGCCCCACCCCGAGGCTTTCGTC
CACTATACCCAGCATCCCCGCTGGACGCGTGAGCAGCTGCCGGAAGAGGGGGACGGGTTGATCCTGTACAAGAACGCGGC
CGAGTATGTGCGCAAAAATCTGGTGTAG

Upstream 100 bases:

>100_bases
GGGGCACGGACGCCACGGGCGCCAAGCTCTGTCCGGAGTGTGGGACCCCACTAGCCTGATACCCCTGATGTCATAAGAAA
TTACTACCATGGAGAAACAG

Downstream 100 bases:

>100_bases
TCCGTTGTTTTCAAGCCTAAGGAGCATCTCCCATGAATTTTACCCGGCCACACGAAGAATGCGGCGTTTTCGGCATCTAT
AACCACAAGGAAGCGGCCAA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRKTRAIVITGNGTNCEMEAAHACRLGGFDEAVIAHIAEILSGEIRLDDFHFLNLTGGFLDGDDLGSAKAQANRLRHASV
AGTDEKLVEQFLRFIRDGKLILGVCNGFQLMVKMGVLPGFDNDYLTQTVTLTHNDCGRFQDRWTYLKVDSESPCVFTSGI
ESGIYLPMRHGEGKFVCDSPQTLERIEGEHLAVFKYSDPDFVRPTMEFPHNPNGSQNAIAGICDASGRLMGLMPHPEAFV
HYTQHPRWTREQLPEEGDGLILYKNAAEYVRKNLV

Sequences:

>Translated_275_residues
MRKTRAIVITGNGTNCEMEAAHACRLGGFDEAVIAHIAEILSGEIRLDDFHFLNLTGGFLDGDDLGSAKAQANRLRHASV
AGTDEKLVEQFLRFIRDGKLILGVCNGFQLMVKMGVLPGFDNDYLTQTVTLTHNDCGRFQDRWTYLKVDSESPCVFTSGI
ESGIYLPMRHGEGKFVCDSPQTLERIEGEHLAVFKYSDPDFVRPTMEFPHNPNGSQNAIAGICDASGRLMGLMPHPEAFV
HYTQHPRWTREQLPEEGDGLILYKNAAEYVRKNLV
>Mature_275_residues
MRKTRAIVITGNGTNCEMEAAHACRLGGFDEAVIAHIAEILSGEIRLDDFHFLNLTGGFLDGDDLGSAKAQANRLRHASV
AGTDEKLVEQFLRFIRDGKLILGVCNGFQLMVKMGVLPGFDNDYLTQTVTLTHNDCGRFQDRWTYLKVDSESPCVFTSGI
ESGIYLPMRHGEGKFVCDSPQTLERIEGEHLAVFKYSDPDFVRPTMEFPHNPNGSQNAIAGICDASGRLMGLMPHPEAFV
HYTQHPRWTREQLPEEGDGLILYKNAAEYVRKNLV

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=252, Percent_Identity=34.5238095238095, Blast_Score=124, Evalue=7e-29,
Organism=Escherichia coli, GI48994899, Length=275, Percent_Identity=31.6363636363636, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17553022, Length=241, Percent_Identity=30.7053941908714, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6321498, Length=283, Percent_Identity=29.3286219081272, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24582111, Length=245, Percent_Identity=33.0612244897959, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24582109, Length=245, Percent_Identity=33.0612244897959, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17137292, Length=245, Percent_Identity=33.0612244897959, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 30648; Mature: 30648

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTRAIVITGNGTNCEMEAAHACRLGGFDEAVIAHIAEILSGEIRLDDFHFLNLTGGFL
CCCEEEEEEECCCCCCEEHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCEEEEEEECCCC
DGDDLGSAKAQANRLRHASVAGTDEKLVEQFLRFIRDGKLILGVCNGFQLMVKMGVLPGF
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHCCCCCC
DNDYLTQTVTLTHNDCGRFQDRWTYLKVDSESPCVFTSGIESGIYLPMRHGEGKFVCDSP
CCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEEEECCCCCEEECCC
QTLERIEGEHLAVFKYSDPDFVRPTMEFPHNPNGSQNAIAGICDASGRLMGLMPHPEAFV
HHHHHCCCCEEEEEEECCCCCCCCHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCHHHE
HYTQHPRWTREQLPEEGDGLILYKNAAEYVRKNLV
EECCCCCCHHHHCCCCCCCEEEECCHHHHHHHHCC
>Mature Secondary Structure
MRKTRAIVITGNGTNCEMEAAHACRLGGFDEAVIAHIAEILSGEIRLDDFHFLNLTGGFL
CCCEEEEEEECCCCCCEEHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCEEEEEEECCCC
DGDDLGSAKAQANRLRHASVAGTDEKLVEQFLRFIRDGKLILGVCNGFQLMVKMGVLPGF
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHCCCCCC
DNDYLTQTVTLTHNDCGRFQDRWTYLKVDSESPCVFTSGIESGIYLPMRHGEGKFVCDSP
CCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEEEECCCCCEEECCC
QTLERIEGEHLAVFKYSDPDFVRPTMEFPHNPNGSQNAIAGICDASGRLMGLMPHPEAFV
HHHHHCCCCEEEEEEECCCCCCCCHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCHHHE
HYTQHPRWTREQLPEEGDGLILYKNAAEYVRKNLV
EECCCCCCHHHHCCCCCCCEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA