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The map label for this gene is nusA [H]

Identifier: 118579397

GI number: 118579397

Start: 1003279

End: 1004484

Strand: Direct

Name: nusA [H]

Synonym: Ppro_0961

Alternate gene names: 118579397

Gene position: 1003279-1004484 (Clockwise)

Preceding gene: 118579396

Following gene: 118579398

Centisome position: 25.03

GC content: 60.53

Gene sequence:

>1206_bases
GTGGAAACGAACATCAGTCTCAAGCACGCCATTGAGCAGATCGTCAAGGAGAAGGGGATCGATCGCCAGGTGGTCCTCGA
AGCCATGGAACAGGCGGTTTTGACGGCCGCCAATAAAAAATACCGCAATACACGCGATCTTGAGGCGCGTTACAATTCCG
ATACCGGCGAGGTTGAGCTGTTCGAGTTCGTCATCGTCGTGGAAGAGGTCGAGGATTCCTACAAGGAGATCAGCCTGGAT
GAGGCCCGCGAAATCGATCCCGATGTGGAGGTCGGCGACTCTCTGGGTGAAAAAATTGATTCCAGCGGCTTTACCCGCAT
TGCGGCCCAGACAGCCAAGCAGGTCATCATCCAGAAGGTGCGCGAAGCCGAGCGGGAGACGATTTTCAACGAGTACAGCG
ACCGCCAGTGGGAGGTTATCACCGGCATGGTACGGCGTTTCGAGAAGGGCGACCTGTTGATCGACCTGGGACGGGCCGAG
GCCGTGCTTCCCTCCAAGGAGCAGATGCCGCGGGAGGTGTACCGCCCCGGCGACCGCATCAGGGCGATCATTACCGATAT
CCGTGTTACCCCCAAGGGGCCGCAGATCATCCTCTCCCGTACCCATCCCAGCATGCTGGCCAAGCTGTTCGAGGCCGAGG
TGCCCGAGGTGGCCGAGGGGATCGTGGAGATTAACGCCATCGTGCGCGATCCGGGCAGCCGCGCCAAGCTGGCCGTTTCC
TCAAACGACCCGGATGTGGATCCGGTGGGCGCCTGCGTCGGCATGCGCGGCTCCCGTGTCCAGAACGTGGTCTCCGAATT
GCGCGGAGAGAAGATCGACATCATTCCCTGGTCCGAGGATATCGCCCGTTTCGCCTGCAACGCCCTCTCGCCGGCTCAGG
TGTCCAAGGTGTTCGTTGATGAGGATAATCGAGCCCTTGAGGTTGTCGTGGCCGACGACCAGCTCTCCCTGGCCATCGGC
AAGCGCGGCCAGAACGTCAGTCTTGCCGCCCGACTGACCGGCTGTCGCATCGACATCAAGAGCGAGGCCAAGGCTGCCGA
GGCTGAGCTGCAGGCCTATGCCTCCTATGATGGCACCCAGCTGGAAGACGAAGAGATGGAAGAGGGTGAGGTGGCGGCTG
ACGAACAGGATGCCGTCGAAACCGATGCCGTTGAAACCGTTGAAACCGTTGAAACCGCGCCCGAAGCGGAAGAGACGGTG
GAGTAA

Upstream 100 bases:

>100_bases
AAGGGCAGACAGCTTCCATACCGCTGGAGCGCATTGCCAAGGCGCAGCTCGAATTCGAATTTTGATCTGATTTCATAGAC
GTCAGCAAGGAGAAGCAACC

Downstream 100 bases:

>100_bases
CGGGGCGCTATGGTCCGTCAGGGTGGTCAGGAAAAACCGCAGCGCAGCTGTCTCGGCTGCCGCGAGACCCGTGACAGGGA
CCGCCTGATCCGTTTCGTGC

Product: transcription elongation factor NusA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
METNISLKHAIEQIVKEKGIDRQVVLEAMEQAVLTAANKKYRNTRDLEARYNSDTGEVELFEFVIVVEEVEDSYKEISLD
EAREIDPDVEVGDSLGEKIDSSGFTRIAAQTAKQVIIQKVREAERETIFNEYSDRQWEVITGMVRRFEKGDLLIDLGRAE
AVLPSKEQMPREVYRPGDRIRAIITDIRVTPKGPQIILSRTHPSMLAKLFEAEVPEVAEGIVEINAIVRDPGSRAKLAVS
SNDPDVDPVGACVGMRGSRVQNVVSELRGEKIDIIPWSEDIARFACNALSPAQVSKVFVDEDNRALEVVVADDQLSLAIG
KRGQNVSLAARLTGCRIDIKSEAKAAEAELQAYASYDGTQLEDEEMEEGEVAADEQDAVETDAVETVETVETAPEAEETV
E

Sequences:

>Translated_401_residues
METNISLKHAIEQIVKEKGIDRQVVLEAMEQAVLTAANKKYRNTRDLEARYNSDTGEVELFEFVIVVEEVEDSYKEISLD
EAREIDPDVEVGDSLGEKIDSSGFTRIAAQTAKQVIIQKVREAERETIFNEYSDRQWEVITGMVRRFEKGDLLIDLGRAE
AVLPSKEQMPREVYRPGDRIRAIITDIRVTPKGPQIILSRTHPSMLAKLFEAEVPEVAEGIVEINAIVRDPGSRAKLAVS
SNDPDVDPVGACVGMRGSRVQNVVSELRGEKIDIIPWSEDIARFACNALSPAQVSKVFVDEDNRALEVVVADDQLSLAIG
KRGQNVSLAARLTGCRIDIKSEAKAAEAELQAYASYDGTQLEDEEMEEGEVAADEQDAVETDAVETVETVETAPEAEETV
E
>Mature_401_residues
METNISLKHAIEQIVKEKGIDRQVVLEAMEQAVLTAANKKYRNTRDLEARYNSDTGEVELFEFVIVVEEVEDSYKEISLD
EAREIDPDVEVGDSLGEKIDSSGFTRIAAQTAKQVIIQKVREAERETIFNEYSDRQWEVITGMVRRFEKGDLLIDLGRAE
AVLPSKEQMPREVYRPGDRIRAIITDIRVTPKGPQIILSRTHPSMLAKLFEAEVPEVAEGIVEINAIVRDPGSRAKLAVS
SNDPDVDPVGACVGMRGSRVQNVVSELRGEKIDIIPWSEDIARFACNALSPAQVSKVFVDEDNRALEVVVADDQLSLAIG
KRGQNVSLAARLTGCRIDIKSEAKAAEAELQAYASYDGTQLEDEEMEEGEVAADEQDAVETDAVETVETVETAPEAEETV
E

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=356, Percent_Identity=42.4157303370786, Blast_Score=304, Evalue=8e-84,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 44391; Mature: 44391

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METNISLKHAIEQIVKEKGIDRQVVLEAMEQAVLTAANKKYRNTRDLEARYNSDTGEVEL
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEH
FEFVIVVEEVEDSYKEISLDEAREIDPDVEVGDSLGEKIDSSGFTRIAAQTAKQVIIQKV
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
REAERETIFNEYSDRQWEVITGMVRRFEKGDLLIDLGRAEAVLPSKEQMPREVYRPGDRI
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCCHHHHCCCHHH
RAIITDIRVTPKGPQIILSRTHPSMLAKLFEAEVPEVAEGIVEINAIVRDPGSRAKLAVS
HHHHHHCEECCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
SNDPDVDPVGACVGMRGSRVQNVVSELRGEKIDIIPWSEDIARFACNALSPAQVSKVFVD
CCCCCCCHHHHHHCCCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCHHHHHEEEEC
EDNRALEVVVADDQLSLAIGKRGQNVSLAARLTGCRIDIKSEAKAAEAELQAYASYDGTQ
CCCCEEEEEEECCCEEEEECCCCCCEEEEEEEECCEEEECCHHHHHHHHHHHHHCCCCCC
LEDEEMEEGEVAADEQDAVETDAVETVETVETAPEAEETVE
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
METNISLKHAIEQIVKEKGIDRQVVLEAMEQAVLTAANKKYRNTRDLEARYNSDTGEVEL
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEH
FEFVIVVEEVEDSYKEISLDEAREIDPDVEVGDSLGEKIDSSGFTRIAAQTAKQVIIQKV
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
REAERETIFNEYSDRQWEVITGMVRRFEKGDLLIDLGRAEAVLPSKEQMPREVYRPGDRI
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCCHHHHCCCHHH
RAIITDIRVTPKGPQIILSRTHPSMLAKLFEAEVPEVAEGIVEINAIVRDPGSRAKLAVS
HHHHHHCEECCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
SNDPDVDPVGACVGMRGSRVQNVVSELRGEKIDIIPWSEDIARFACNALSPAQVSKVFVD
CCCCCCCHHHHHHCCCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCHHHHHEEEEC
EDNRALEVVVADDQLSLAIGKRGQNVSLAARLTGCRIDIKSEAKAAEAELQAYASYDGTQ
CCCCEEEEEEECCCEEEEECCCCCCEEEEEEEECCEEEECCHHHHHHHHHHHHHCCCCCC
LEDEEMEEGEVAADEQDAVETDAVETVETVETAPEAEETVE
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]