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The map label for this gene is trxB/A [H]

Identifier: 118579292

GI number: 118579292

Start: 899885

End: 900277

Strand: Reverse

Name: trxB/A [H]

Synonym: Ppro_0855

Alternate gene names: 118579292

Gene position: 900277-899885 (Counterclockwise)

Preceding gene: 118579293

Following gene: 118579291

Centisome position: 22.46

GC content: 58.02

Gene sequence:

>393_bases
ATGAGAAAGCTCATCATTGGAACAATTTTGGCGCTCTCCTGCCTGGCCCACCTGTCGGCGCTGGCGGCGGAACTTCCTTC
CGCAACCGGCAGCAGCATCCGGGCTGCCTTGAGCTCCGGCAGGCCCAGCGTAGTCGACTTCGGCGCCCGCAGCTGCATCC
CCTGCAAGAAGATGGCGCCCATACTGGAAGAGCTGAACCGCGAGCTCAAGGGCAAGGCCAACGTGCTCTTCAACGATGTA
TGGAAAGATGATGTCCTGGCGAGGGATTACCGCATACAGATGATCCCGACCCAGATCTTCTTCAACGCCGCAGGCAAAGA
GGTCAAGCGCCACATGGGCTTCATGGACAAGGCCGACATACTGAAGGAACTGAAGGCACTGGGTTTGAAATGA

Upstream 100 bases:

>100_bases
TCATGAAATACGGCGTGATGAGCACCCCGGCCCTGGTCATCGACGGCACGGTGGTGTTTTCCGGCAAGAGCGCTTCAGCC
GCCGAAATCCAGAAATACCT

Downstream 100 bases:

>100_bases
GCCTGCTGGACAACGTGGAGCAGATCATCAGCCTTTACCCACTGCTGGCTTTCGTCGCGGTCTTTTGTGCCGGGGTGCTG
TCGTCGGCCTCCCCCTGCGT

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: Thioredoxin reductase; TRXR; Thioredoxin [H]

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MRKLIIGTILALSCLAHLSALAAELPSATGSSIRAALSSGRPSVVDFGARSCIPCKKMAPILEELNRELKGKANVLFNDV
WKDDVLARDYRIQMIPTQIFFNAAGKEVKRHMGFMDKADILKELKALGLK

Sequences:

>Translated_130_residues
MRKLIIGTILALSCLAHLSALAAELPSATGSSIRAALSSGRPSVVDFGARSCIPCKKMAPILEELNRELKGKANVLFNDV
WKDDVLARDYRIQMIPTQIFFNAAGKEVKRHMGFMDKADILKELKALGLK
>Mature_130_residues
MRKLIIGTILALSCLAHLSALAAELPSATGSSIRAALSSGRPSVVDFGARSCIPCKKMAPILEELNRELKGKANVLFNDV
WKDDVLARDYRIQMIPTQIFFNAAGKEVKRHMGFMDKADILKELKALGLK

Specific function: Efficient Electron Donor For The Essential Enzyme Ribonucleotide Reductase. Is Also Able To Reduce The Interchain Disulfide Bridges Of Insulin. [C]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF00085 Thioredoxin [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 14240; Mature: 14240

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLIIGTILALSCLAHLSALAAELPSATGSSIRAALSSGRPSVVDFGARSCIPCKKMAP
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEECCCCCCCCCHHHHHH
ILEELNRELKGKANVLFNDVWKDDVLARDYRIQMIPTQIFFNAAGKEVKRHMGFMDKADI
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHCCCCCHHHH
LKELKALGLK
HHHHHHHCCC
>Mature Secondary Structure
MRKLIIGTILALSCLAHLSALAAELPSATGSSIRAALSSGRPSVVDFGARSCIPCKKMAP
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEECCCCCCCCCHHHHHH
ILEELNRELKGKANVLFNDVWKDDVLARDYRIQMIPTQIFFNAAGKEVKRHMGFMDKADI
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHCCCCCHHHH
LKELKALGLK
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969512; 7476189; 11234002 [H]